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16 Levertumoren

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Leverziekten
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Samenvatting

De diverse diagnostische mogelijkheden die tegenwoordig beschikbaar zijn en het toegenomen gebruik hiervan heeft ertoe geleid dat er steeds vaker focale leverafwijkingen aangetoond worden als toevalsbevinding. Het merendeel van de laesies die buiten een follow-upprogramma van een reeds bekende maligniteit worden ontdekt, zijn benigne van aard.

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Literatuur

  1. Schwartz LH, Gandras EJ, Colangelo SM, Ercolani MC, Panicek DM. Prevalence and importance of small hepatic lesions found at CT in patients with cancer. Radiology 1999;210:71–74.

    Article  CAS  PubMed  Google Scholar 

  2. Hussain SM, Semelka RC. Liver masses. Magn Reson Imaging Clin N Am 2005;13:255–275.

    Article  PubMed  Google Scholar 

  3. Hussain SM, Semelka RC. Hepatic imaging: comparison of modalities. Radiol Clin North Am 2005;43:929–947, ix.

    Google Scholar 

  4. Semelka RC, Martin DR, Balci C, Lance T. Focal liver lesions: comparison of dual-phase CT and multisequence multiplanar MR imaging including dynamic gadolinium enhancement. J Magn Reson Imaging 2001;13:397–401.

    Article  CAS  PubMed  Google Scholar 

  5. Helmberger T, Semelka RC. New contrast agents for imaging the liver. Magn Reson Imaging Clin N Am 2001;9:745–766, vi.

    Google Scholar 

  6. Semelka RC, Helmberger TK. Contrast agents for MR imaging of the liver. Radiology 2001;218:27–38.

    Article  CAS  PubMed  Google Scholar 

  7. Regev A, et al. Large cystic lesions of the liver in adults: a 15-year experience in a tertiary center. J Am Coll Surg 2001;193:36–45.

    Article  CAS  PubMed  Google Scholar 

  8. Karavias DD, et al. Simple (non-parasitic) liver cysts: clinical presentation and outcome. Hepatogastroenterology 2000;47:1439–1443.

    CAS  PubMed  Google Scholar 

  9. Brunt EM. Benign tumors of the liver. Clin Liver Dis 2001;5:1–15, v.

    Google Scholar 

  10. Terkivatan T, Hussain SM, De Man RA, IJzermans JN. Diagnosis and treatment of benign focal liver lesions. Scand J Gastroenterol Suppl 2006:102–115.

    Google Scholar 

  11. Rooks JB, et al. Epidemiology of hepatocellular adenoma. The role of oral contraceptive use. JAMA 1979;242:644–648.

    Article  CAS  PubMed  Google Scholar 

  12. Libbrecht L, et al. Hepatic progenitor cells in hepatocellular adenomas. Am J Surg Pathol 2001;25:1388–1396.

    Article  CAS  PubMed  Google Scholar 

  13. Foster JH, Berman MM. The malignant transformation of liver cell adenomas. Arch Surg 1994;129:712–717.

    Article  CAS  PubMed  Google Scholar 

  14. Terkivatan T, et al. Treatment of ruptured hepatocellular adenoma. Br J Surg 2001;88:207–209.

    Article  CAS  PubMed  Google Scholar 

  15. Terkivatan T, Wilt JH de, Man RA de, IJzermans JN. Management of hepatocellular adenoma during pregnancy. Liver 2000;20:186–187.

    Article  CAS  PubMed  Google Scholar 

  16. Borght S Van Der, Libbrecht L, Katoonizadeh A, Aerts R, Nevens F, Verslype C, Roskams TA. Nuclear b-catenin staining and absence of steatosis are indicators of hepatocellular adenomas with an increased risk of malignancy. Histopathology 2007;51: 855–856.

    Article  PubMed  Google Scholar 

  17. Terkivatan T, et al. Indications and long-term outcome of treatment for benign hepatic tumors: a critical appraisal. Arch Surg 2001;136:1033–1038.

    Article  CAS  PubMed  Google Scholar 

  18. Trotter JF, Everson GT. Benign focal lesions of the liver. Clin Liver Dis 2001;5:17–42, v.

    Article  CAS  PubMed  Google Scholar 

  19. Mathieu D, et al. Oral contraceptive use and focal nodular hyperplasia of the liver. Gastroenterology 2000;118:560–564.

    Article  CAS  PubMed  Google Scholar 

  20. Sadowski DC, Lee SS, Wanless IR, Kelly JK, Heathcote EJ. Progressive type of focal nodular hyperplasia characterized by multiple tumors and recurrence. Hepatology 1995;21:970–975.

    Article  CAS  PubMed  Google Scholar 

  21. Gaffey MJ, Iezzoni JC, Weiss LM. Clonal analysis of focal nodular hyperplasia of the liver. Am J Pathol 1996;148:1089–1096.

    CAS  PubMed Central  PubMed  Google Scholar 

  22. Weimann A, et al. Benign liver tumors: differential diagnosis and indications for surgery. World J Surg 1997;21:983–990.

    Article  CAS  PubMed  Google Scholar 

  23. Charny CK, et al. Management of 155 patients with benign liver tumours. Br J Surg 2001;88:808–813.

    Article  CAS  PubMed  Google Scholar 

  24. Terkivatan T, Hussain SM, Lameris JS, IJzermans JN. Transcatheter arterial embolization as a safe and effective treatment for focal nodular hyperplasia of the liver. Cardiovasc Intervent Radiol 2002;25:450–453.

    Article  PubMed  Google Scholar 

  25. Reddy KR, et al. Benign and solid tumors of the liver: relationship to sex, age, size of tumors, and outcome. Am Surg 2001;67: 173–178.

    CAS  PubMed  Google Scholar 

  26. Iqbal N, Saleem A. Hepatic hemangioma: a review. Tex Med 1997;93:48–50.

    CAS  PubMed  Google Scholar 

  27. Terkivatan T, et al. Size of lesion is not a criterion for resection during management of giant liver haemangioma. Br J Surg 2002;89:1240–1244.

    Article  CAS  PubMed  Google Scholar 

  28. Lauffer JM, et al. Biliary cystadenocarcinoma of the liver: the need for complete resection. Eur J Cancer 1998;34:1845–1851.

    Article  CAS  PubMed  Google Scholar 

  29. Semelka RC, Hussain SM, Marcos HB, Woosley JT. Biliary hamartomas: solitary and multiple lesions shown on current MR techniques including gadolinium enhancement. J Magn Reson Imaging 1999;10: 196–201.

    Article  CAS  PubMed  Google Scholar 

  30. Nonomura A, Mizukami Y, Kadoya M. Angiomyolipoma of the liver: a collective review. J Gastroenterol 1994;29:95–105.

    Article  CAS  PubMed  Google Scholar 

  31. Sawai H, Manabe T, Yamanaka Y, Kurahashi S, Kamiya A. Angiomyolipoma of the liver: case report and collective review of cases diagnosed from fine needle aspiration biopsy specimens. J Hepatobiliary Pancreat Surg 1998;5:333–338.

    Article  CAS  PubMed  Google Scholar 

  32. Mahli H, Gores GJ. Review article: the modern diagnosis and therapy of cholangiocarcinoma. Aliment Pharmacol ther 2006; 23:1287–1296.

    Article  Google Scholar 

  33. Singhal D, van Gulik TM, Gouma DJ. Palliative management of hilar cholangiocarcinoma. Surg Oncol 2005; 14: 59–74.

    Article  CAS  PubMed  Google Scholar 

  34. Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C. Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis 2008; 28 (3):302–314.

    Article  PubMed  Google Scholar 

  35. Lerut J, Weber M, Orlando G, Dutkowski P. Vascular and rare liver tumors: a good indication for liver transplantation? J Hepatol 2007;47: 454–475.

    Article  Google Scholar 

  36. Finegold.MJ, Egler RA, Gos JA, Guillerman RP, Karpen SJ, Krishnamurthy R, O’Mahony CO. Liver tumors: pediatric population. Liver Transpl 2008;14: 1545–1556.

    Article  PubMed  Google Scholar 

  37. Verhoef C, et al. Hepatocellular carcinoma in the Netherlands incidence, treatment and survival patterns. Eur J Cancer 2004;40:1530–1538.

    Article  CAS  PubMed  Google Scholar 

  38. Taylor-Robinson SD, Foster GR, Arora S, Hargreaves S, Thomas HC. Increase in primary liver cancer in the UK, 1979-94. Lancet 1997;350:1142–1143.

    Article  CAS  PubMed  Google Scholar 

  39. Stipa F, et al. Outcome of patients with fibrolamellar hepatocellular carcinoma. Cancer 2006;106:1331–1338.

    Article  PubMed  Google Scholar 

  40. Libbrecht L, et al. Focal lesions in cirrhotic explant livers: pathological evaluation and accuracy of pretransplantation imaging examinations. Liver Transpl 2002;8:749–761.

    Article  PubMed  Google Scholar 

  41. Verhoef C, Valkema R, Man RA de, Krenning EP, Yzermans JN. Fluorine-18 FDG imaging in hepatocellular carcinoma using positron coincidence detection and single photon emission computed tomography. Liver 2002;22:51–56.

    Article  CAS  PubMed  Google Scholar 

  42. Trevisani F, et al. Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti- HCV status. J Hepatol 2001;34:570–575.

    Article  CAS  PubMed  Google Scholar 

  43. Durand F, et al. Assessment of the benefits and risks of percutaneous biopsy before surgical resection of hepatocellular carcinoma. J Hepatol 2001;35:254–258.

    Article  CAS  PubMed  Google Scholar 

  44. Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis 1999;19:329–338.

    Article  CAS  PubMed  Google Scholar 

  45. Prospective validation of the CLIP score: a new prognostic system for patients with cirrhosis and hepatocellular carcinoma. The Cancer of the Liver Italian Program (CLIP) Investigators. Hepatology 2000;31: 840–845.

    Article  Google Scholar 

  46. Verhoef C, et al. Good outcomes after resection of large hepatocellular carcinoma in the non-cirrhotic liver. Dig Surg 2004;21:380–386.

    Article  CAS  PubMed  Google Scholar 

  47. Llovet JM, Schwartz M, Mazzaferro V. Resection and liver transplantation for hepatocellular carcinoma. Semin Liver Dis 2005;25:181–200.

    Article  PubMed  Google Scholar 

  48. Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet 2003;362:1907–1917.

    Article  PubMed  Google Scholar 

  49. Mazzaferro V, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996;334:693–699.

    Article  CAS  PubMed  Google Scholar 

  50. Llovet JM, Schwartz M, Fuster J, Bruix J. Expanded criteria for hepatocellular carcinoma through downstaging prior to liver transplantation: not yet there. Semin Liver Dis 2006;26:248–253.

    Article  PubMed  Google Scholar 

  51. Adam R, et al. Liver resection as a bridge to transplantation for hepatocellular carcinoma on cirrhosis: a reasonable strategy? Ann Surg 2003;238:508–518.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Jansen MC, et al. Outcome of regional and local ablative therapies for hepatocellular carcinoma: a collective review. Eur J Surg Oncol 2005;31:331–347.

    Article  CAS  PubMed  Google Scholar 

  53. Chen MS, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg 2006;243:321–328.

    Article  PubMed Central  PubMed  Google Scholar 

  54. Huang GT, et al. Percutaneous ethanol injection versus surgical resection for the treatment of small hepatocellular carcinoma: a prospective study. Ann Surg 2005;242:36–42.

    Article  PubMed Central  PubMed  Google Scholar 

  55. Yoshida H, et al. Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C. Gut 2004;53:425–430.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  56. Llovet JM, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359:378–390.

    Article  CAS  PubMed  Google Scholar 

  57. Khan SA, Miras A, Pelling M, Taylor-Robinson SD. Cholangiocarcinoma and its management. Gut 2007; 56:1755–1756.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  58. Blechacz B, Gores GJ. Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology 2008;48:308–321.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  59. Ben Menachem T. Risk factors for cholangiocarcinoma. Eur J Gastroenterol Hepatol 2007;19:615–617.

    Article  PubMed  Google Scholar 

  60. Miller G, Schwartz LH, D’Angelica M. The use of imaging in the diagnosis and staging of hepatobiliary malignancies. Surg Oncol Clin N Am 2007;16:343–368.

    Article  PubMed  Google Scholar 

  61. Bipat S, et al. Evidence-base guideline on management of colorectal liver metastases in the Netherlands. Neth J Med 2007;65:5–14.

    CAS  PubMed  Google Scholar 

  62. Joosten J, Ruers T. Local radiofrequency ablation techniques for liver metastases of colorectal cancer. Crit Rev Oncol Hematol 2007;62:153–163.

    Article  CAS  PubMed  Google Scholar 

  63. Cummings LC, Payes JD, Cooper GS. Survival after hepatic resection in metastatic colorectal cancer: a population-based study. Cancer 2007;109:718–726.

    Article  PubMed  Google Scholar 

  64. Choti MA, et al. Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann Surg 2002;235:759–766.

    Article  PubMed Central  PubMed  Google Scholar 

  65. Poon RT, et al. Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database. Ann Surg 2004;240:698–708.

    PubMed Central  PubMed  Google Scholar 

  66. Gollub MJ, Schwartz LH, Akhurst T. Update on colorectal cancer imaging. Radiol Clin North Am 2007;45: 85–118.

    Article  PubMed  Google Scholar 

  67. Adam R, et al. Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases? Ann Surg 2004;240:1052–1061.

    Article  PubMed Central  PubMed  Google Scholar 

  68. Pawlik TM, et al. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann Surg 2005;241:715–722, discussion.

    Google Scholar 

  69. Abdalla EK, et al. Improving resectability of hepatic colorectal metastases: expert consensus statement. Ann Surg Oncol 2006;13:1271–1280.

    Article  PubMed  Google Scholar 

  70. Clavien PA, Petrowsky H, DeOliveira ML, Graf R. Strategies for safer liver surgery and partial liver transplantation. N Engl J Med 2007;356:1545–1559.

    Article  PubMed  Google Scholar 

  71. Pfannschmidt J, Dienemann H, Hoffmann H. Surgical resection of pulmonary metastases from colorectal cancer: a systematic review of published series. Ann Thorac Surg 2007;84:324–338.

    Article  PubMed  Google Scholar 

  72. Jaeck D. The significance of hepatic pedicle lymph nodes metastases in surgical management of colorectal liver metastases and of other liver malignancies. Ann Surg Oncol 2003;10:1007–1011.

    Article  PubMed  Google Scholar 

  73. Jain S, Sacchi M, Vrachnos P, Lygidakis NJ, Andriopoulou E. Recent advances in the treatment of colorectal liver metastases. Hepatogastroenterology 2005; 52:1567–1584.

    PubMed  Google Scholar 

  74. Leen E, Horgan PG. Radiofrequency ablation of colorectal liver metastases. Surg Oncol 2007;16:47–51.

    Article  PubMed  Google Scholar 

  75. Punt CJ. [Medicamenteuze behandeling van patiënten met colorectumcarcinoom]. Ned Tijdschr Geneeskd 2005;149:1441–1447.

    CAS  PubMed  Google Scholar 

  76. Adam R, et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg 2004; 240:644–657.

    Article  PubMed Central  PubMed  Google Scholar 

  77. Adam R, et al. Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal. Ann Surg Oncol 2001;8:347–353.

    Article  CAS  PubMed  Google Scholar 

  78. D’Angelica M, et al. Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: a matched case-control study. Ann Surg Oncol 2007;14:759–765.

    Article  PubMed  Google Scholar 

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Terkivatan, T., Verhoef, C., IJzermans, J., de Man, R.A. (2009). 16 Levertumoren. In: Janssen, H., Drenth, J., van Hoek, B. (eds) Leverziekten. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-313-7437-3_16

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  • DOI: https://doi.org/10.1007/978-90-313-7437-3_16

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