Abstract
The purpose of this study is to visualize topographical changes of serum proteins, albumin and IgG, passing through the mouse glomerular capillary loops and their reabsorption in renal proximal tubules by immunohistochemistry in combination with our “in vivo cryotechnique.” Under the acute hypertensive condition, the albumin and kappa or lambda light chains, but not IgG1 heavy chain, were strongly immunolocalized in the apical cytoplasm of almost all proximal tubules. This study is the first in vivo visualization for glomerular passage of serum proteins and their transtubular absorption.
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Li, Z., Terada, N., Ohno, N., Ohno, S. (2016). Immunohistochemical Analyses on Albumin and IgG in Acute Hypertensive Mouse Kidneys. In: Ohno, S., Ohno, N., Terada, N. (eds) In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55723-4_20
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DOI: https://doi.org/10.1007/978-4-431-55723-4_20
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