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Der Gastrointestinaltrakt mit der Aufgabe des Nahrungstransports, der Nährstoff-, Wasser- und Elektrolytresorption und der Elimination unverdaulicher Nahrungsbestandteile, stellt aufgrund seiner Barrierefunktion zwischen innerem und äußerem Milieu und dem damit einhergehendem permanenten Antigenreiz das größte immunologische Organ des Organismus dar. Akute Erkrankungen des Abdomens, Sepsis, Beatmung oder Medikamente können zum Bild des mechanischen oder paralytischen Ileus oder bis hin zum manifesten Darmversagen führen, respektive kann eine gestörte gastrointestinale Funktion systemischen Entzündungsreaktionen (SIRS, Sepsis) induzieren oder unterhalten.

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Ragaller, M., Gottschlich, B. (2006). Akutes Darmversagen in der Intensivmedizin. In: Engelmann, L., Schuster, HP. (eds) Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen. Steinkopff. https://doi.org/10.1007/978-3-7985-1729-5_7

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  • DOI: https://doi.org/10.1007/978-3-7985-1729-5_7

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