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Receptor-mediated Effects of Drugs on the Eye

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Metipranolol

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Abstract

Numerous functions of the eye such as width of pupils, accommodation, possibly also secretion of aqueous humour and the facility of its outflow are regulated almost exclusively via the autonomic nervous system. The dense innervation (for review, see [26]) (for example that of the M. sphincter and M. dilatator pupillae with sympathetic fibers which originate from the ganglion cervicale superius and flow into the muscular effector cells via the Nn. ciliares breves and longi) guarantee a potential release of noradrenaline at the sympathetic nerve endings (Fig. 1). By stimulation of the post-synaptic α 1-adrenoceptors noradrenaline produces a contraction of smooth muscle and, via β-adrenoceptors, a relaxation of smooth muscle.

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Author information

Authors and Affiliations

  1. Center of Pharmacology, Clinic of the Johann-Wolfgang-Goethe University, Frankfurt/Main, Federal Republic of Germany

    Prof. Dr. D. Palm

  2. Zentrum der Pharmakologie, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, D-6000, Frankfurt/Main, Federal Republic of Germany

    Prof. Dr. D. Palm

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  1. Prof. Dr. D. Palm
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Editor information

Editors and Affiliations

  1. Isar — Technical University, Munich, Federal Republic of Germany

    Hanns-Jürgen Merté (Director of the Eye Infirmary and Outpatient Eye Clinic rechts) (Director of the Eye Infirmary and Outpatient Eye Clinic rechts)

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© 1984 Springer-Verlag Wien

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Palm, D. (1984). Receptor-mediated Effects of Drugs on the Eye. In: Merté, HJ. (eds) Metipranolol. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4067-3_2

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  • DOI: https://doi.org/10.1007/978-3-7091-4067-3_2

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-81824-4

  • Online ISBN: 978-3-7091-4067-3

  • eBook Packages: Springer Book Archive

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