Skip to main content
SpringerLink
Log in

Therapieoptionen bei Rezidiven von Tumoren des Peritoneums

  • Chapter
Peritoneale Tumoren und Metastasen

  • 1630 Accesses

Zusammenfassung

Obwohl die zytoreduktive Chirurgie (CRS) in Kombination mit hyperthermer intraperitonealer Chemotherapie (HIPEC) in kurativer Intention zum Einsatz kommen, zeigt die klinische Realität, dass ein Großteil der Patienten im weiteren Verlauf ein Rezidiv entwickelt. In vielen Fällen bleibt dabei das Rezidiv ausschließlich auf das Peritoneum beschränkt. Für Patienten mit einem isolierten peritonealen Rezidiv nach CRS und HIPEC gibt es aktuell kein standardisiertes Vorgehen. Einem Teil dieser Patienten kann – unter Berücksichtigung der Tumorentität, der Tumorbiologie und der zu erwartenden postoperativen Lebensqualität – als Individualentscheidung eine weitere CRS und HIPEC angeboten werden. Durch dieses aggressive Vorgehen konnten im gemischten Patientengut für verschiedene Tumorentitäten 1-, 3- und 5-Jahres-Überlebensraten von 92 %, 60 % und 34 % erzielt werden

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 139.00
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Alzahrani N (2016) Repeat cytoreductive Surgery and hyperthermic intraperitoneal chemotherapy in colorectal cancer in 189 patients (PSOGI colaboration) Journal of peritoneum (and other serosal surfaces). JoPER 1: 5–6

    Google Scholar 

  • Bijelic L, et al. (2007) Failure analysis of recurrent disease following complete cytoreduction and perioperative intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from colorectal cancer. Ann Surg Oncol 14: 2281–2288

    Article  Google Scholar 

  • Bijelic L, et al. (2008) Treatment failure following complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from colorectal or appendiceal mucinous neoplasms. J Surg Oncol 98: 295–299

    Article  Google Scholar 

  • Chua TC, et al. (2013) Iterative cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent peritoneal metastases. J Surg Oncol 108: 81–88

    Article  Google Scholar 

  • Esquivel J, et al. (2001) Second-look surgery in patients with peritoneal dissemination from appendiceal malignancy: analysis of prognostic factors in 98 patients. Ann Surg 234: 198–205

    Article  CAS  Google Scholar 

  • Golse N, et al. (2012) Iterative procedures combining cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal recurrence: postoperative and long-term results. J Surg Oncol 106: 197–203

    Article  Google Scholar 

  • Ihemelandu C, et al. (2015) Iterative cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent or progressive diffuse malignant peritoneal mesothelioma: clinicopathologic characteristics and survival outcome. Ann Surg Oncol 22: 1680–1685

    Article  Google Scholar 

  • Klaver YL, et al. (2013) Secondary cytoreductive surgery and peri-operative intraperitoneal chemotherapy for peritoneal recurrence of colorectal and appendiceal peritoneal carcinomatosis following prior primary cytoreduction. J Surg Oncol 107: 585–590

    Article  Google Scholar 

  • Saxena A, et al. (2010) Critical assessment of preoperative and operative risk factors for complications after iterative peritonectomy procedures. Eur J Surg Oncol 36: 309–314

    Article  CAS  Google Scholar 

  • Vassos N, et al. (2016) Repeated cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with recurrent peritoneal carcinomatosis. World J Surg Oncol 14: 42

    Google Scholar 

  • Yan TD, et al. (2007) Critical analysis of treatment failure after complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from appendiceal mucinous neoplasms. Ann Surg Oncol 14: 2289–2299

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Krankenhaus Barmherzige Brüder Regensburg, Klinik für Allgemein- und Viszeralchirurgie, Prüfeninger Straße 86, 93049, Regensburg, Deutschland

    Dr. H. Leebmann & Prof. Dr. med. Dr. h.c. P. Piso

Authors
  1. Dr. H. Leebmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prof. Dr. med. Dr. h.c. P. Piso
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to H. Leebmann or P. Piso .

Editor information

Editors and Affiliations

  1. Charité Campus Virchow-Klinikum, Berlin, Deutschland

    Beate Rau

  2. Krankenhaus Barmherzige Brüder, Regensburg, Deutschland

    Pompiliu Piso

  3. Universitätsklinikum Tübingen, Tübingen, Deutschland

    Alfred Königsrainer

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Deutschland

About this chapter

Cite this chapter

Leebmann, H., Piso, P. (2018). Therapieoptionen bei Rezidiven von Tumoren des Peritoneums. In: Rau, B., Piso, P., Königsrainer, A. (eds) Peritoneale Tumoren und Metastasen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54500-3_40

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-54500-3_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-54499-0

  • Online ISBN: 978-3-662-54500-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation