Zusammenfassung
Kutane Lymphome (KL) stellen die zweithäufigste Form extranodaler Non-Hodgkin-Lymphome dar und repräsentieren eine klinisch, histologisch, phänotypisch und prognostisch heterogene Gruppe kutaner Neoplasien. Die Inzidenz der KL beträgt 5–10 Fälle pro 1 Million Einwohner pro Jahr, wobei die kutanen T-Zell-Lymphome (KTZL) die Mehrheit (65 %) der KL ausmachen. Die Klassifikation folgt dem sog. Multiparameter-Prinzip, bei welchem die einzelnen Lymphomentitäten durch eine charakteristische Konstellation klinischer, histologischer, immunphänoty pischer und genetischer Merkmale definiert sind. Die diagnostische Zuordnung von KL hat daher unter Berücksichtigung aller Parameter zu erfolgen. Der histologischen Beurteilung und insbesondere der klinisch-pathologischen Korrelation kommt eine zentrale Rolle in der Diagnostik der KL zu.
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Kempf, W., Cerroni, L. (2016). Kutane Lymphome und Leukämien. In: Cerroni, L., Garbe, C., Metze, D., Kutzner, H., Kerl, H. (eds) Histopathologie der Haut. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45133-5_38
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