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Plasmafraktionierung

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Transfusionsmedizin

Zusammenfassung

Das menschliche Blutplasma enthält mehr als 120 heute bekannte Proteine. Mit Hilfe der Plasmafraktionierung in großtechnischem Maßstab wird versucht, einzelne Eiweißfraktionen für den therapeutischen Einsatz bei Patienten mit fehlenden oder funktionell defekten Plasmaproteinen herzustellen. So gewonnene Plasmaderivate sind v. a. bei Gerinnungsstörungen, Eiweißmangel und Antikörpermangelsyndromen von Bedeutung. Manche Plasmaproteine lassen sich inzwischen auch gentechnisch herstellen. Es ist zu erwarten, daß mit der zunehmenden Kenntnis der Funktion weiterer Plasmaproteine und den Möglichkeiten zu ihrer gentechnischen Produktion deren Einsatz eine enorme Ausweitung erfahren wird.

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  1. N. Heimburger
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  1. Institut für Klinische Immunologie und Transfusionsmedizin der Universität, Langhansstr. 7, D-35385, Gießen, Deutschland

    Christian Mueller-Eckhardt

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Heimburger, N., Haupt, H. (1996). Plasmafraktionierung. In: Mueller-Eckhardt, C. (eds) Transfusionsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10599-3_16

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