Abstract
The short arm of human chromosome 12 represents approximately 1.5% of the human genome. The cytogenetic analysis of 12p by classical banding techniques is therefore limited to the detection of quantitative or major structural alterations.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Albig W, Kardanilou E, Drabent B, Zimmer A, Doenecke D (1991) Isolation and characterisation of two human H1 histone genes within clusters of core histone genes. Genomics 10:940–948
Burton FH, Loeb DD, Voliva CF, Martin SL, Edgell MH, Hutchinson CA (1986) Conservation throughout mammalia and extensive protein-encoding capacity of the highly repeated DNA long interspersed sequence one. J Mol Biol 187:291–304
Bernardi G (1989) The isochore organisation of the human genome. Annu Rev Genet 23:637–661
Castedo SMMJ, deJong B, Oosterhuis JW, Seruca R, Indenbury WJ Buist J, Sleijfer DT (1988) i(12p) negative testicular germ cell tumors a different group? Cancer Genet Cytogenet 35:171–178
Craig IW, McBride OW (1991) Report of the committee on the genetic constitution of chroomosome 12. Cytogenet Cell Genet 58:555–579
Dal Cin P, Drochmans A, Moerman P, Van den Berghe H (1989) Isochromosome 12p in a mediastinal germ cell tumor. Cancer Genet Cytogenet 42:243–251
de Jong B, Oosterhuis JW, Castedo SMMJ, Vos A, te Meerman GJ (1990) Pathogenesis of adult testicular germ cell tumors. Cancer Genet Cytogen 48:143–167
Delozier-Blanchet CD, Engel E, Wolt H (1985) Isochromosome 12p in malignant testicular tumors. Cancer Genet Cytogenet 15:375–376
Ercolani L, Florence B, Denaro M, Alexander M (1988) Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene. J Biol Chem 263: 15335–15341
Holmquist GP, Gray M, Porter T, Jordan J (1982) Characterisation of Giemsa dark- and lightband DNA. Cell 31:121–129
Kievits T, Dauwerse JG, Wiegant J, Deville P, Breuning MH, Cornelisse CJ, van Ommen G-J, Pearson PL (1990) Rapid subchromosomal localisation of cosmids by nonradioactive in situ hybridisation. Cytogenet Cell Genet 53:134–136
Korenberg JR, Rykowski MC (1988) Human chromosome organisation: alu, lines, and the molecular structure of metaphase chromosome bands. Cell 53:391–400
Lichter P, Tang CC, Call K, Hermanson G, Evans GA, Housman D, Waed DC (1990) High resolution mapping of uman chromosome 11 by in situ hybridisation with cosmid clones. Science 247:64–69
Parimoo S, Patanjali SR, Shukla H, Chaplin DD, Weissman SM (1991) cDNA selection: efficient approach for the selection of cDNA’s encoded in large chromosomal DNA fragments. Proc Natl Acad Sci USA 88:9623–9627
Suijkerbuijk RF, Van de Veen AY, Van Echten J, Buys CHCM, De Jong B, Oosterhuys JW, Warburton DA, Cassiman J-J, Schonk D, Van Kessel AG (1991) Demonstration of the genuine iso-12p character of the standard marker chromosome of testicular germ cell tumor and identification of further chromosome 12 aberrations by competitive in situ hybridisation. Am J Hum Genet 48:269–273
Van Ness J, Maxwell IH, Hahn WE (1979) Complex population of nonpolyadenylated messenger RNA in mouse brain. Cell 18:1342–1349
van Ommen GJB, Verkerk JMH (1986) Restriction analysis of chromosomal DNA in a size range up to two million base pairs by pulsed field gradient electrophoresis. In: Davies KE (ed) Human genetic diseases. A practical approach. •• pp 113–133
Yunis JJ (1981) Mid-prophase human chromosomes. The attainment of 2000 bands. Hum Genet 56:293–298
Zhang J, Marynen P, Devriendt K, Frijns J-P, Van den Berghe H, Cassiman J-J (1989) Molecular analysis of the isochromosome 12p in the Pallister-Killian syndrome. Hum Genet 83:359–363
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zhang, J., Baens, M., Chaffanet, M., Aerssens, J., Cassiman, JJ., Marynen, P. (1994). Isolation and Characterisation of NotI-end Cosmids Mapping to Human Chromosome 12p. In: Bullerdiek, J., Bartnitzke, S. (eds) Chromosome 12 Aberrations in Human Solid Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06255-5_17
Download citation
DOI: https://doi.org/10.1007/978-3-662-06255-5_17
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-06257-9
Online ISBN: 978-3-662-06255-5
eBook Packages: Springer Book Archive