Abstract
In addition to metabolic products common to all organisms, e.g. nucleotides, nucleic and amino acids, proteins and carbohydrates, the so-called primary metabolic products, there are specialized products originally (pre-1950) found exclusively in plants, though not in all plants.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References and Further Reading
Albersheim P, Darvill AG (1985) Oligosaccharins. Sci Am 253 (3): 44
Alfermann AW, Spieler H, Reinhard E (1985) Biotransformation of cardiac glycosides by Digitalis cell cultures in airlift reactors. In: Neumann KH, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg New York, p 316
Amann M, Wanner G, Zenk MH (1986) Intracellular compartmentation of two enzymes of berberine biosynthesis in plant cell cultures. Planta 167 (3): 310
Arens H, Stöckigt J, Weiler EW, Zenk MH (1978) Radioimmunoassays for the determination of the indole alkaloids ajmalicine and serpentine in plants. Planta Med 34: 37
Arens H, Borbe HO, Ulbrich B, Stöckigt J (1982) Detection of percin, a new CNS active indole alkaloid from Picralima nitida cell suspension culture by opiate receptor binding studies. Planta Med 46: 210
Axelos M, Teyssendier de la Serve B, Peaud-Lenoel T (1987) Level of messenger RNA encoding small subunit ribulose bisphosphate carboxylase is enhanced by cytokinins in tobacco cell suspension cultures. Biochemie 69: 671
Bailey JA, Mainsfield JW (eds) (1982) Phytoalexins. Blackie, Glasgow
Balandrin MF, Kloche JA, Wurtele ES, Bollinger WH (1985) Natural plant chemicals: sources of industrial and medicinal materials. Science 228: 1154
Barz W (1975) Abbau von Aromastoffen und heterozyklischen Pflanzeninhaltsstoffen durch Zellsuspensionskulturen, Planta Med Suppl. Thieme Verlag, Stuttgart, p 128
Barz W, Reinhard E, Zenk MH (eds) (1977) Plant tissue and its biotechnological application. Springer, Berlin Heidelberg New York
Barz W, Daniel S, Hinderer W, Jaques U, Kessmann U, Köster J, Tiemann K (1988) Elicitation and metabolism of phytoalexins in plant cell biotechnology. In: Pais MSS, Mavituna F, Novais IM (eds) Plant cell cultures. NATO ASI Series H: Cell Biology, vol 18. Springer, Berlin Heidelberg New York, p 211
Barz W, Beimer A, Dräger B, Jaques U, Otto Ch, Super E, Upmeier B (1990) Turnover and storage of secondary products in cell culture. In: Charlwood BA, Rhodes MJC (eds) Secondary products from plant tissue culture. Proc of the Phytochemical Society of Europe 30, Oxford Science Publication, Calderon Press, Oxford, p 79
Becker H, Sauerwein M (1990) Manipulating the biosynthetic capacity of plant cell cultures. In: Charlwood BV, Rhodes MJ (eds) Secondary products from plant tissue culture. Proc of the Phytochemical Society of Europe 30. Calderon Press, Oxford, p 44
Berlin J, Sasse F (1985) Selection and screening techniques for plant cell cultures. In: Fiechter A (ed) Plant cell culture. Advances in biochemical engineering/biotechnology 32. Springer, Berlin Heidelberg New York, p 99
Berlin J, Beier H, Fecker L, Forche E, Noe W, Sasse F, Schiel O, Wray V (1985) Conventional and new approaches to increase the alkaloid production of plant cell cultures. In: Neumann KH, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg New York, p 272
Bolwell GP, Cramer CL, Lamb CJ, Schuch W, Dixon RA (1986) L-Phenyl-alanine-ammonia-lyase from Phaseolus vulgaris. Modulation of the levels of active enzyme by trans-cinnamic acid. Planta 169: 97
Briens B, Hahibrock K, Schäfer E (1986) Fluence dependence of the ultra-violet light induced accumulation of chalcone synthase mRNA and effects of blue and far-red light in cultured parsley cells. Planta 169: 393
Brodelius P (1988) Stress induced secondary metabolism in plant cell cultures. In: Pais MSS, Mavituna F, Novais JM (eds) Plant cell biotechnology. Proc NATO Advanced Study Institute on Plant Cell Biotechnology, Series H: Cell Biology 18. Springer, Berlin Heidelberg New York, p 195
Brodelius P, Mosbach K (1982) Immobilized plant cells. In: Laskin AI (ed) Advances in applied microbiology, vol 28. Academic Press, New York, p 1
Brodelius P, Nilsson K (1983) Permeabilization of immobilized plant cells, resulting in release of intracellulary stored products with preserved cell viability. Eur J Appl Microb Biotechnol 17 (5): 275
Brown EG, Newton RP (1981) Cyclic AMP and higher plants. Phytochemistry. 20: 2453
Brown JT, Chalwood BV (1986) The control of callus formation and differentiation in scented pelargoniums. J Plant Physiol 123: 409
Brown JT, Hegarty PK, Charlwood BV (1987) The toxicity of mono-terpenes to plant cell cultures. Plant Sci 48: 195
Chappell J, Hahlbrock K (1984) Transcription of plant defence genes in response to UV light or fungal elicitor. Nature 311: 76
Charlwood BV, Brown JT, Moustou C, Charlwood KA (1988) Pelargoniums: flavours, fragrances and the new technology. Plants Today 1 (2): 42
Cheung WY (ed) (1983) Calcium and cell function, vol IV. Academic Press, New York
Cho GH, Kim DJ, Pedersen H, Chin CK (1988) Etephen enhancement of secondary metabolite synthesis in plant cell cultures. Biotechnol Prog 4 (3): 184
Conrad K (1974) Ein sensibilisierter Amaranthus-Cytokinin-Test. Biochem Physiol Pflanzen (BPP) 165: 531
Coscia CI (1978) Proposed feedback of regulation of geraniol hydroxylase by indole alkaloids (Vinca rosea). In: Waller GR, Nowacki EK (eds) Alkaloid biology and metabolism in plants. Plenum Press, New York, p 247
Coxon DT (1982) Phytoalexins from other plant families. In: Bailey JA, Mansfield JW (eds) Phytoalexins. Blackie, Glasgow, p 106
Cresswell RC (1986) Selection studies on Catharanthus roseus. In: Morris P, Scragg AH, Stafford A, Fowler MW (eds) Secondary metabolism in plant cell cultures. University Press, Cambridge, p 230
Czygan F-C (1975) Möglichkeiten zur Produktion von Arzneipflanzen durch pflanzliche Gewebekulturen. Planta Med Suppl 169
Czygan F-C (ed) (1984) Biogene Arzneistoffe. Vieweg, Braunschweig
Darvill AG, Albersheim P (1984) Phytoalexins and their elicitors. A defense against microbial infection in plants. Annu Rev Plant Physiol 35: 243
Davis BD (1955) Intermediates in amino acid biosynthesis. Adv Enzymol 16: 247
Deus-Neumann B, Zenk MH (1984) Instability of indole alkaloid production in Catharanthus roseus cell suspension cultures. Planta Med 50: 427
Dhawan AK, Malik CP (1974) Cyclic AMP control of some oxido-reductases during pine pollen germination and tube growth. Phytochemistry 18: 2015
DiCosmo F, Misawa A (1985) Eliciting secondary metabolism in plant cell cultures. Trends Biotechnol 3 (12): 318
Dieter P (1984) Calmodulin and calmodulin mediated processes in plants. Plant Cell Environ 7: 371 Dixon RA (1986) The phytoalexin response: elicitation, signalling and host gene expression. Biol Rev 61: 239
Dougall DK, Weyrauch KW (1980) Growth and anthocyan production by carrot suspension cultures grown under chemostat conditions with phosphate as limiting nutrient. Biotechnol Bioeng 22: 337
Dougall DK, LaBrake S, Whitten GH (1983) The effects of limiting nutrients, dilution rate, culture pH, and temperature on the yield constant and anthocyan accumulation of carrot cells grown in semicontinuous chemostat cultures. Biotechnol Bioeng 25: 569
Drapeau D, Sauvaire Y, Blanch HW, White CR (1986) Improvement of diosgenin yield from Dioscorea deltoidea plant cell cultures by use of non-traditional hydrolysis method. Planta Med 6: 474
Ebel J (1986) Phytoalexin synthesis: biochemical analysis of the induction process. Annu Rev Plant Pathol 24: 235
Eilert U, Kurz WGW, Constabel F (1985) Stimulation of sanguinarine accumulation in Papaver somniferum cell cultures by fungal elicitors. J Plant Physiol 119: 65
Eilert U, Constabel F, Kurz WGW (1986) Elicitor stimulation of monoterpene indole alkaloid
formation in suspension cultures of Catharanthus roseus. J Plant Physiol 128: 11
Eilert U, Kurz WGW, Constabel F (1987) Ultrastructure of Catharanthus roseus cells cultured in vitro and exposed to conditions for alkaloid accumulation. Protoplasma 140: 157
Ellis RJ (1986) Photoregulation of plant gene expression. BioSci Rep 6 (2): 127
Endreß R (1977) Einfluß möglicher Phosphodiesterase Inhibitoren und cAMP auf die BetacyanAkkumulation. Phytochemistry 16: 1549
Endreß R (1979) Allosteric regulation of phosphodiesterase from Portulaca callus by cGMP and papaverine. Phytochemistry 18: 15
Endreß R (1985) Regulation der DPOA (Betacyan)-Akkumulation: Hypothese einer cAMP-Beteiligung. 33. Vortragstagung, Gesellschaft für Arzneipflanzenforschung, Regensburg. Pharmaz Z+g 37: 6
Endreß R, Jäger A, Kreis W (1984) Catecholamine biosynthesis dependent on the dark in betacyanin forming Portulaca callus. J Plant Physiol 115: 291
Ettlinger C, Lehle L (1988) Auxin induces rapid changes in phosphatidyl-inositol metabolites. Nature 331 (6152): 176
Felix H (1982) Permeabilized cells. Anal Biochem 120: 211
Fowler MW (1987) Process systems and approaches for large scale plant cell culture. In: Green CE, Somers DA, Hackett WP, Biesboer DD (eds) Plant tissue and cell culture. Plant biology 3. Liss, New York, p 21
Fowler MW (1988) Problems in commercial exploitation of plant cell cultures. In: Bock G, Marsh J (eds) Applications of plant cell and tissue culture. Ciba Foundation Symposium 137. Wiley, Chichester, p 239
Fowler MW, Stepan-Sarkissian G (1983) Chemicals from plant cell fermentation. Adv Biotechnol Proc 2: 135
Fritsch H, Hahlbrock K, Grisebach H (1971) Biosynthese von Cyanidin in Zellsuspensionskulturen von Haplopappus gracilis. Z Naturforsch 26b: 581
Fujita Y, Hara Y, Suga C, Morimoto T (1981) Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon of shikonin derivatives. Plant Cell Rep 1: 61
Garve R, Luckner M, Vogel E, Tewes A, Nover L (1980) Growth, morphogenesis and cardenolide formation in long-time cultures of Digitalis lanata. Planta Med 40: 92
Gaspar T (1986) Integrated relationships of biochemical and physiological peroxidase activities. In: Greppin H, Pinel C, Gaspar T (eds) Molecular and physiological aspects of plant peroxidases. University of Geneva, Centre Botanique, p 455
Gottmann K, Schäfer E (1982) Comparative studies of the phytochrome system in cell cultures from different plants. Plant Cell Rep 1: 221
Grisebach H (1986) Phytoalexin accumulation. In: Kleinkauf H, von Döhren H, Dorauer H, Nesemann G (eds) Regulation of secondary metabolite formation. Worksh Conf, Hoechst 16, VCH, Weinheim, p 355
Hahlbrock K (1977) Regulatory aspects of phenylpropanoid biosynthesis in cell culture. In: Barz W, Reinhard E, Zenk MH (eds) Plant tissue culture and its biotechnological application. Springer, Berlin Heidelberg New York, p 95
Hahlbrock K, Kuhlen E, Lindl T (1971) Änderungen von Enzymaktivitäten während des Wachstums von Zellsuspensionskulturen von Glycine max: Phenylalanin ammonium lyase und p-cumarat: CoA Ligase. Planta 99: 311
Hahlbrock K, Betz B, Gardiner SE, Kreuzaler F, Matern U, Ragg H, Schäfer E, Schröder J (1978) Enzyme induction in cultured cells. In: Thorpe TA (ed) Frontiers of plant tissue culture. Proc 4th Int Congr Plant tissue and cell culture, held at the Univ Calgary, Alberta, Canada. International Association for Plant Tissue Culture, University of Calgary. Offset Printing Services, p 317
Hahlbrock K, Schröder J, Vieregge J (1980) Enzyme regulation in parsley and soybean cell cultures. Adv Biochem Eng 18: 39
Hahlbrock K, Kreuzaler F, Ragg HH, Faulz E, Kuhn DN (1982) Regulation of flavonoid and phytoalexin accumulation through mRNA and enzyme induction in cultured plant cells. In: Jaenicke L (ed) Biochemistry of differentiation and morphogenesis. 33. Colloq der Gesellschaft für Biol Chem, März 1982 in Mosbach/Baden, Springer, Berlin Heidelberg New York, p 34
Halverson LJ, Stacey G (1986) Signal-exchange in plant-microbe interactions. Microbiol Rev 50 (2): 193
Hara Y, Yoshioha T, Morimoto T, Fujita Y, Yamada Y (1988) Enhancement of berberine production in suspension cultures of Coptis japonica by gibberellic acid treatment. J Plant Physiol 133: 12
Harborne JB (1980) Plant phenolics. In: Bell EA, Charlwood BV (eds) Secondary plant products. Encyclopedia of Plant Physiology, New Series, vol 8. Springer, Berlin Heidelberg New York, p 329
Heide L (1988) Das chinesische Heilmittel Shikonin. In: Bio-und Gentechnologie in Nordrhein-Westfalen. BioEng 2: 144
Heide L, Tabata M (1987) Enzyme activities in cell-free extracts of shikonin-producing Lithospermum erythrorhizon cell suspension cultures. Phytochemistry 26 (6): 1645
Heim S, Wagner KG (1987) The phosphatidylinositol species of suspension cultured plant cells. Z Naturforsch 42C: 1003
Herrera-Estrella L, DeBlock M, Messeus E, Hernalsteens JP, Van Montagu M, Schell J (1983)
Chimeric genes as dominant selectable markers in plant cells. EMBO J 2 (6):987
Heuptee RB van, Tam AS (1988) Peptides released by cultured peanut cells during growth. J Plant Physiol 133: 645
Hinderer W, Flentje U, Barz W (1987) Microsomal isoflavone 2’- and 3’-hydroxylases from chickpea (Cicer arietinum L.) cell suspension cultures induced for pterocarpan phytoalexin formation. FEBS Lett 214: 101
Hirotani M, Furuya T (1977) Restoration of cardenolide synthesis in redifferentiated shoots from callus of Digitalis purpurea. Phytochemistry 16: 610
Hoekstra SS, Harkes PAA, Libbenga KR (1988) Screening of calli and compact globular structures of Cinchona ledgeriana for production of quinone alkaloids. In: Robins RJ, Rhodes MJC (eds) Manipulating secondary metabolism in culture. University Press, Cambridge, p 96
Hsu A-F (1981) Effect of protein synthesis inhibitors on cell growth and alkaloid production in cell cultures of Papaver somniferum. J Nat Prod 44 (4): 408
Hüsemann W, Callies R, Leibfritz D (1992) External pH modifies the intracellular pH and the mode of photosynthetic CO, assimilation in photoautotrophic cell suspension cultures of Chenopodium rubrum L. Bot Acta 105: 116
Hutin M, Foucher JR, Courtois D, Petiard V (1983) Evidences for unusual forms of storage of morphinan in a Papaver somniferum L. tissue culture. C R Acad Sci Paris III 297: 47
Igbavboa U, Sieweke H-J, Leistner E, Röwer I, Hüsemann W, Barz W (1985) Alternative formation of anthraquinones and lipoquinones in heterotrophic and photoautotrophic cell suspension cultures of Morinda lucida Benth. Planta 166: 537
Jaenicke L (ed) (1982) Biochemistry of differentiation and morphogenesis. Springer, Berlin Heidelberg New York
Janistyn B (1986) Effects of adenosine-3’-5’-monophosphate (cAMP) on the activity of soluble protein kinases in maize (Zea mays) coleoptile homogenates. Z Naturforsch C Biosci 41 (5–6): 579
Jensen RA (1986) The shikimate/arogenate pathway: link between carbohydrate metabolism and secondary metabolism. Physiol Plant 66: 164
Joersbo M, Brunstedt J (1991) Electroporation mechanism and transient expression, stable transformation and biological effects in plant protoplasts. Physiol Plant 81: 256
Kartnig Th, Kobosil P (1977) Beobachtungen über das Vorkommen und die Bildung von Cardenoliden in Gewebekulturen aus Digitalis purpurea and Digitalis lanata. Planta Med 31: 221
Kaulen H, Schell J, Kreuzaler F (1986) Light-induced expression of the chimeric chalcone synthase-NPT II gene in tobacco cells. EMBOJ 5 (1): 1
Kaus H (1987) Some aspects of calcium dependent regulation in plant metabolism. Annu Rev Plant Physiol 28: 47
Knobloch K-H, Berlin J (1983) Influence of phosphate on the formation of the indole alkaloids and phenolic compounds in cell suspension cultures of Catharanthus roseus. I. Comparison of enzyme activities and product accumulation. Plant Cell Tissue Organ Cult 2: 333
Knoop B, Beiderbeck R (1983) Adsorbenskultur — ein Weg zur Steigerung der Sekundärstoffproduktion in pflanzlichen Suspensionskulturen. Z Naturforsch 38c: 4484
Kreis W (1987) Untersuchungen zur Kompartimentierung der Cardenolid-Biotransformation in Digitalis lanata Zellkulturen. PhD Thesis, Universität Tübingen
Kreis W, Reinhard E (1989) The production of secondary metabolites by plant cells cultivated in bioreactors. Planta Med 55: 409
Kurosaki F, Tsurusawa Y, Nishi A (1987a) The elicitation of phytoalexins by Ca’ and cyclic AMP in carrot cells. Phytochemistry 26: 1919
Kurosaki F, Tsurusawa Y, Nishi A (19876) Breakdown of phosphatidylinositol during the elicitaion of phytoalexin production in cultured carrot cells. Plant Physiol 85: 601
Lawton MA, Dixon RA, Lamb CJ (1988) Nuclear protein binding to a cis-acting silencer in a defense gene promotor. J Cell Biochem Suppl 12C: 268
Lehtola T, Huhtikangas A, Virtanen R (1982) Application of radioimmunoassays to the quantitation of hyoscyamine in plant material. Planta Med 45: 237
Leistner E (1985) Biosynthesis of chorismate derived quinones in plant cell cultures. In: Neumann K-H, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg New York, p 215
Levin R, Gaba V, Tal B, DeNola D, Vasil J (1988) Automated plant tissue culture for mass propagation. Bio Technol 6 (9): 1035
Lindsey K (1985) Manipulation, by nutrient limitation, of the biosynthetic activity of immobilised cells of Capsicum frutescens Mill. cv. Annuum. Planta 165: 126
Lindsey K, Jones MGK (1989) Plant biotechnology in agriculture. Open University Press, Wiley, Chichester, p 59
Lindsey K, Yeoman MM (1983) Novel experimental systems for studying the production of secondary metabolites by plant tissue cultures. In: Mantell SH, Smith H (eds) Plant biotechnology. Society for Experimental Biology. Seminar Series 18. University Press, Cambridge, p 39
Lockwood GB (1984) Alkaloids of cell suspensions derived from four Papaver spp. and the effect of temperature stress. Z Pflanzenphysiol 114: 361
Luckner M (1971) Was ist Sekundärstoffwechsel? Pharmazie 26: 717
Luckner M (1986) Secondary metabolism in microorganisms, plants, and animals. Springer, Berlin Heidelberg New York
Luckner M, Nover L (1977) Expression of secondary metabolism. An aspect of cell specialization of microorganisms, higher plants, and animals. In: Luckner M, Nover L, Böhm H (eds) Secondary metabolism and cell differentiation. Mol Biol Biochem Biophys 23: 1
Luckner M, Nover L, Böhm H (eds) (1977) Secondary metabolism and cell differentiation. Mol Biol Biochem Biophys 23
Mäder M (1985) Zur enzymatischen Differenzierung der pflanzlichen Zellwand. BIUZ 15 (5): 141
Mangat BS, Janjua S (1987) Cyclic nucleotides and in vitro plant cultures. J Exp Bot 38 (197): 2059
Mantell SH, Smith H (1984) Cultural factors that influence secondary metabolite accumulations in plant cell and tissue cultures. In: Mantell SH, Smith H (eds) Plant biotechnology. Society for Experimental Biology, Seminar Series 18. University Press, Cambridge, p 75
Marion-Poll A, Caboche M (1984) Relationship between auxin and amino acid metabolism of tobacco protoplast-derived cells. Plant Physiol 75: 1048
Matile P (1978) Biochemistry and function of vacuoles. Annu Rev Plant Physiol 29: 193
Matile P (1984) Das toxische Kompartiment der Pflanzenzelle. Naturwissenschaften 71: 18
Mehdy MC, Lamb CJ (1987) Chalcone isomerase cDNA cloning and mRNA induction by fungal elicitor, wounding and infection. EMBO J 6: 1527
Meravy L, Cvikrova M, Hrubcova M (1988) The effect of DMSO on extraction of proteins and phenolic substrates by Nicotiana tabacum cells into culture medium. Biol Plant 30 (4): 241
Mizukami H, Konoshima M, Tabata M (1977) Effects of nutritional factors on shikonin derivative formation in Lithospermum callus cultures. Phytochemistry 16: 1183
Mizusaki S, Tanabe Y, Noguchi M, Tamaki E (1971) p-Coumaroyl-putrescine, caffeoylputrescine and feruloylputrescine from callus tissue culture of Nicotiana tabacum. Phytochemistry 10: 1347
Moesta P, West CA (1985) Casbene synthetase: regulation of phytoalexin biosynthesis in Ricinus communis L. seedlings. Arch Biochem Biophys 238: 325
Mol JNM, Schram AW, Gerats AGM, Kreuzaler F, Hahlbrock K, Reif Hi, Veltkamp E (1984) Regulation of flavonoid gene expression in Petunia hybrida: identification and characterisation of a mutant in chalcone synthase gene expression suitable for genetic engineering. In: Houwink EH, van der Meer RR (eds) Innovations in biotechnology 20. Elsevier, Amsterdam, p 469
Morris P (1986) Regulation of product synthesis in cell cultures of Catharanthus roseus. Effect of culture temperature. Plant Cell Rep 5: 427
Morris P, Gibbs S (1986) Uptake, binding and metabolism of morphine alkaloids by cell cultures of Papaver somniferum. In: Morris P, Scragg,AH, Stafford A, Fowler MW (eds) Secondary metabolism in plant cell cultures. University Press, Cambridge, p 137
Muranaka Y, Ejiri S, Katsumata T (1985) Effects of dibutyryl cyclic AMP and dibutyryl cyclic GMP on the changes in invertase, lipase, and some dehydrogenase activities during germination of pine pollen. Agric Biol Chem 49 (2): 1943
Musker D, Collin HA, Britton G, Ollerhead G (1988) Propenyl cysteine sulphoxide biosynthesis in callus cultures of Allium cepa. In: Robins RJ, Rhodes MJC (eds) Manipulating secondary metabolism in culture. University Press, Cambridge, p 177
Nagel M, Reinhard E (1975) Das ätherische ÖI der Kalluskulturen von Ruta graveolens. II. Physiologie zur Bildung des ätherischen Öles. Planta Med 27: 264
Niemann GJ (1976) Phenolics from Larix needles. XII. Seasonal variation of main flavonoids in leaves of Larix leptolepis. Acta Bot Neerl 25: 349
Noe W, Berlin J (1985) Induction of de-novo synthesis of tryptophan decarboxylase in cell suspensions of Catharanthus roseus. Planta 166: 500
Nover L, Lynen F, Mothes K (1980) Cell compartmentation and metabolic channeling. Fischer, Jena
Ogino T, Hiraoka N, Tabata M (1978) Seclection of high nicotine producing cell lines of tobacco callus by single cell cloning. Phytochemistry 17: 1907
Ohl S, Hahlbrock K, Schäfer E (1989) A stable blue-light derived signal modulates ultraviolet-light induced activation of the chalcone-synthase gene in cultured parsley cells. Planta 177: 228
Ozeki Y, Komamine A (1985) Induction of anthocyanin synthesis in relation to embryogenesis in a carrot suspension culture — a model system for the study of expression and repression of secondary metabolism. In: Neumann K-H, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg, New York, p 99
Parr AJ, Robins RJ, Rhodes MJC (1986) Product release from plant cells grown in culture. In: Morris P, Scragg AH, Stafford A, Fowler MW (eds) Secondary metabolism in plant cell cultures. University Press, Cambridge, p 173
Pearson DW (1978) Nicotine production by tobacco tissue cultures. PhD Thesis, Nottingham University
Phillips R, Henshaw GG (1977) The regulation of synthesis of phenolics in stationary phase cell cultures of Acer pseudoplatanus L. J Exp Bot 28: 785
Poovaiah BW, Reddy ASN, McFadden JJ (1987) Calcium messenger system: role of protein phosphorylation and inositol phospholipids. Physiol Plant 69: 569
Radin DN (1986) A modell cell culture system to study isoprenoid regulation in plants. Curr Top Plant Biochem Physiol 5: 153
Rajagopal R (1980) Significance of cyclic nucleotides in amaranthin synthesis by Amaranthus caudatus seedlings. Ann Bot 46: 641
Randolph TW (1990) Supercritical fluid extractions in biotechnology. Trends Biotechnol 8 (3): 78
Ranjeva R, Boudet AM, Harada M, Marigo G (1975) Phenolic metabolism in petunia tissues. I. Characteristic responses of enzymes involved in different steps of polyphenol synthesis to different hormonal influences. Biochim Biophys Acta 399: 23
Reinhard E, Corduan G, Volk OH (1968) Ãœber Gewebekulturen von Ruta graveolens. Planta Med 16: 8
Reinhard E, Corduan G, von Broche W (1971) Untersuchungen über das ätherische Öl und die Cumarine in Gewebekulturen von Ruta graveolens. Herba Hung 10: 9
Renaudin JP, Guern J (1990) Transport and vacuolar storage of secondary metabolites in plant cell cultures. In: Charlwood BA, Rhodes MJC (eds) Secondary products from plant tissue culture. Proc Phytochemical Society of Europe 30. Oxford Science Publications, Calderon Press, Oxford, p 59
Rhodes MJC, Hamill J, Parr AJ, Robins RJ, Walton NJ (1988) Strain improvement by screening and selection techniques. In: Robins RJ, Rhodes MJC (eds) Manipulating secondary metabolism in culture. University Press, Cambridge, p 82
Richter G, Beckmann J, Groß M, Hundrieser J, Schneider Ch (1982) Blue light induced synthesis of chloroplast proteins in cultured plant cells. In: Back N, Brewer GJ, Eisvogel VP, Grover R, Hirschhorn K, Kety SS, Udenfried S, Uhr JW (eds) Progress in clinical and biological research, vol 102. B. Cell function and differentiation. Liss, New York, p 267
Richter G, Dudel A, Einspanier R, Dannhauer J, Hüsemann W (1987) Blue light control of m-RNA level and transcription during the chloroplast differentiation in photomixotrophic and photoautotrophic cell cultures (Chenopodium rubrum L.) Planta 172: 79
Robbins MR, Dixon RA (1984) Induction of chalcone isomerase in elicitor treated bean cells. Comparison of rates of synthesis and appearance of immunodetectable enzymes. Eur J Biochem 145: 195
Robins RJ, Rhodes MJC (1986) Polymeric adsorbents stimulate anthraquinone production by cell suspension cultures of Cinchona ledgeriana. In: Morris P, Scragg AH, Stafford A, Fowler MW (eds) Secondary metabolism in plant cell cultures. University Press, Cambridge, p 35
Rokem JS, Goldberg I (1985) Secondary metabolites from plant cell suspension cultures: methods for yield improvement. Adv Biotechnol Proc 4: 241
Rolfs CH, Schön H, Steffens M, Kindl H (1987) Cell suspension culture of Arachis hypogea L: model system of specific enzyme induction in secondary metabolism. Planta 172: 238
Röper W, Schulze M, Chaouiche E, Melch KA (1985) Nicotine production by tissue cultures of tobacco as influenced by various culture parameters. J Plant Physiol 118: 463
Rudge K, Morris P (1986) The effect of osmotic stress on growth and alkaloid accumulation in Catharanthus roseus. In: Morris P, Scragg AH, Stafford A, Fowler MW (eds) Secondary metabolism in plant cell cultures. University Press, Cambridge, p 75
Ryan CA (1987) Oligosaccharide signalling in plants. Annu Rev Cell Biol 3: 295
Ryan CA, Walker-Simmons M (1983) Plant vacuoles. Methods Enzymol 96: 580
Sakuta M, Takagi T, Komamine A (1987) Effects of sucrose on betacyanin accumulation and growth in suspension cultures of Phytolacca americana. Physiol Plant 71: 455
Scheebror H, Bjork L, Schulz U, Neumann D, Diettrich B, Luckner M (1989) The influence of inhibitors of chloroplast differentiation on chlorophyll and cardenolide accumulation in somatic embryos of Digitalis lanata. Biochem Physiol Pflanz 184: 63
Schell JS (1987) Transgenic plants as tools to study the molecular organisation of plant genes. Science 237: 1176
Schlee D (1986) Ökologische Biochemie. Springer, Berlin Heidelberg New York
Schmidt WE, Ebel J (1987) Specific binding of a fungal glucan phytoalexin elicitor to membrane fractions from soybean Glycine max. Proc Natl Acad Sci USA 84: 4117
Seidel S, Reinhard E (1987) Major cardenolide glycosides in embryogenic suspension cultures of Digitalis lanata. Planta Med 3: 308
Senger H (ed) (1987) Blue light responses: phenomena and occurrence in plant and microorganisms. CRC Press, Boca Raton
Sharma R (1984) Phytochrome — a plant photochromic sensor. J Sci Ind Res 43: 615
Sharma R (1985) Yearly review: phytochrome regulation of enzyme activity in higher plants. Phytochem Photobiol 41 (6): 747
Shaw G (1971) The chemistry of sporopollenin. In: Luckner M,Nover L, Böhm H (eds) Secondary metabolism and cell differentiation. Mol Biol Biochem Biophys 23: 72
Shuler ML (1981) Production of secondary metabolites from plant tissue culture — problems and prospects. Ann NY Acad Sci 369: 65
Shuler ML (1985) Bioreactor consideration for chemical production from plant cell cultures. In: Day P, Zaitlen M, Hollaender A (eds) Biotechnology in plant science: relevance to agriculture in the eighties. Academic Press, Orlando, p 191
Smith DA, Banks SW (1986) Biosynthesis, elicitation and biological activity of isoflavonoid phytoalexins. Phytochemistry 25 (5): 979
Smith JI, Smart NJ, Kurz WGW, Misawa M (1987a) The use of organic and inorganic compounds to increase the accumulation of indole alkaloids in Catharanthus roseus cell suspension cultures. J Exp Bot 38 (94): 1501
Smith JI, Smart NJ, Kurz WGW, Misawa M (1987b) Stimulation of indole alkaloid production in cell suspension cultures of Catharanthus roseus by abscisic acid. Planta Med 4: 470
Spieler H, Alfermann AW, Reinhard E (1985) Biotransformation of ß-methyldigitoxin by cell cultures of Digitalis lanata in airlift and stirred tank reactors. Appl Microbiol Biotechnol 23: 1
Staba EJ (ed) (1980) Plant tissue culture as a source of biochemicals. CRC Press, Boca Raton
Steck W, Gamborg OL, Bailey BK (1973) Increased yields of alkaloids through precursor biotransformation in cell suspension cultures of Ruta graveolens. Lloydia 36: 93
Steinbiß H-H, Schell J (1987) Chimäre Gene — Ihre Bedeutung für Grundlagenforschung und angewandte Pflanzenzüchtung. Z Naturforsch 42c: 1011
Suzuki M, Kakagawa K, Fukui H, Tabata M (1987) Relationship of berberine-producing capability between Thalictrum plants and their tissue cultures. Plant Cell Rep 6: 260
Tabata M, Fujita Y (1985) Production of shikonin by plant cell cultures. In: Day P, Zaitlen M, Hollaender A (eds) Biotechnology in plant science: relevance to agriculture in the eighties. Academic Press, Orlando, p 207
Tabata M, Mizukami H, Hiraoka A, Konoshima M (1974) Pigment formation in callus cultures in Lithospermum erythrorhizon. Phytochemistry 13: 927
Tabata H, Onigo T, Yoshioka K, Yoshikawa N, Hiraoka N (1978) Selection of cell lines with higher yield of secondary products. In: Thorpe TA (ed) Frontiers of plant tissue culture 1978, Proc 4th Int Congr of Plant tissue and cell culture, held at the University of Calgary, Alberta, Canada, Aug 20–25. International Association for Plant Tissue Culture, University of Calgary, Offset Printing Services, p 213
Thomas B, Johnson CB (eds) (1991) Phytochrome properties and biological action. NATO ASI Series, Series H: Cell Biology, vol 50. Springer, Berlin Heidelberg New York
Thompson WF, Kaufman LS, Watson JC (1985) Induction of plant gene expression by light. BioEssays 3 (4): 153
Threfall DR, Whitehead JM (1988a) The use of metal ions to induce the formation of secondary products in plant tissue culture. In: Robins RJ, Rhodes MJC (eds) Manipulating secondary metabolism in culture. University Press, Cambridge, p 51
Timko MP, Kausch AP, Castresana C, Fassler J, Herrera-Estrella L, van den Broeck G, van Montagu M, Schell J, Cashmore AR (1985) Light regulation of plant gene expression by an upstream enhancer-like element. Nature 318: 579
Tissut M, Egger KK (1972) Les glycosides flavoniques foliaires de quelques arbres au cours du cycle vegetatif. Phytochemistry 11: 631
Tulecke W, Nickell LG (1959) Production of large amounts of plant tissue by submerged culture. Science 130: 863
Tunen Ai van, Koes RE, Spelt CE, van der Krol AR, Stuitje AR, Mol JNM (1988) Cloning the two chalcone flavanone isomerase genes from Petunia hybrida: coordinate, light-regulated and differential expression of flavonoid genes. EMBO J 7 (5): 1257
Verpoorte R, Wijnsma R, Mulder-Krieger Th, Harkes PAA, Baerheim Svendsen A (1985) Plant cell tissue culture of Cinchona species. In: Neumann K-H, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell cultures. Springer, Berlin Heidelberg New York, p 196
Vickery ML, Vickery B (1981) Secondary plant metabolism. McMillan Press, London
Wagner F, Vogelmann H (1977) Cultivation of plant tissue cultures in bioreactors and formation of secondary metabolites. In: Barz W, Reinhard E, Zenk MH (eds) Plant tissue and its biotechnological application. Springer, Berlin Heidelberg New York
Waller GR, Nowaki EK (1978) Alkaloid biology and metabolism in plants. Plenum Press, New York, p 247
Weissenböck G, Reznik H (1970) Änderung des Flavonoidmusters während der Samenkeimung von Impatiens balsamina L. Z Pflanzenphysiol 63: 114
West CA (1981) Fungal elicitors of the phytoalexin response in higher plants. Naturwissenschaften 68: 447
Wichers HJ, Malingre TM, Hnizing HJ (1983) The effect of some environmental factors on the production of L-DOPA by alginate entrapped cells of Mucuna pruriens. Planta 158: 482
Wiermann R (1973) Über die Beziehung zwischen Flavonol aufbauenden Enzymen, einem Flavonol umwandelnden Enzym und der Akkumulation phenylpropanoider Verbindungen während der Antherenentwicklung. Planta (Berl) 110: 353
Wink M (1984) Evidence for an extracellulare lytic compartment of plant cell suspension cultures: the cell culture medium. Naturwissenschaften 71: 635
Wink M (1985) Composition of the spent cell culture medium. 1. Time course of ethanol formation and the excretion of hydrolytic enzymes into the medium of suspension-cultured cells of Lupinum polyphyllus. J Plant Physiol 121 (3): 287
Wink M (1987) Quinolizidin alkaloids: biochemistry, metabolism, and function in plants and cell suspension cultures. Planta Med 53 (6): 509
Wink M, Hartmann Th (1982) Diurnal fluctuation of quinolizidine alkaloid accumulation in legume plants and photomixotrophic cell suspension cultures. Z Naturforsch 37c: 369
Yamada Y, Hashimoto T, Endo T, Yukimune Y, Kohno J, Hamaguchi N, Dräger B (1990) Biochemistry of alkaloid production in vitro. In: Charlwood BV, Rhodes MJC (eds) Secondary products from plant tisue culture. Proc Phytochemical Society of Europe 30. Oxford Science Publications, Calderon Press, Oxford, p 227
Yamamoto H, Nakagawa K, Fukui H, Tabata M (1986) Cytological changes associated with alkaloid production in cultured cells of Coptis japonica and Thalictrum minus. Plant cell Rep 5: 65
Yeoman MM, Lindsey K, Miedzybrodzka MB, McLauchlan WR (1982) Accumulation of secondary products as effect of differentiation in plant cell and tissue cultures. In: Yeomann MM, Truman DES (eds) Differentiation in vitro, vol 4. British Society for cell Biology Symp, Univ Press, Cambridge, p 65
Yeoman MM, Holden MA, Corchet P, Holden PR, Goy JG, Hobbs MC (1990) Exploitation of disorganized plant cultures for the production of secondary metabolites. In: Charlwood BV, Rhodes MJC (eds) Secondary products from plant tissue culture. Proc of the phytochemical Society of Europe, vol 30. Oxford Science Publications, Calderon Press, p 139
Yoshikawa M, Sugimoto K, Masago M (1988) Receptor on soybean membranes for the elicitors released from cell walls of Phythophthora megasperma f. sp. glycina by soybean ß-1, 3-glucanase. Abstr of Papers for the 5th Int Congr of Plant pathology, Kyoto, Japan, p 216
Zenk M-H (1976) Das physiologische Potential pflanzlicher Zellkulturen. Rheinisch Westfälische Akademie der Wissenschaften, Vortrag 257. Westdeutscher Verlag, Düsseldorf, p 27
Zenk M-H (1978) The impact of plant cell cultures, a potential source of pharmaceuticals. In: Thorpe TA (ed) Frontiers of plant tissue culture 1978. Proc 4th Int Congr of Plant tissue and cell culture, held at the Univ Calgary, Alberta, Canada, Aug 20–25. International Association for Plant Tissue Culture, University of Calgary, Offset Printing Services, p 1
Zenk MH, El-Shagi H, Schulte U (1975) Anthraquinone production by cell suspension cultures of Morinda citrifolia. Planta Med Suppl 79
Zenk M-H, El-Shagi H, Arens H, Stöckigt J, Weiler E, Deus B (1977) Formation of the indole alkaloids serpentine and ajmalicine in cell suspension cultures of Catharanthus roseus. In: Barz W, Reinhard, E, Zenk M-H (eds) Plant tissue culture and its biotechnological application. Springer, Berlin Heidelberg New York, p 27
Zenk M-H, Rueffer M, Kutchan T, Galneder M (1988) Biotechnological approaches to the production of isoquinoline alkaloids. In: Bock G, Marsh J (eds) Applications of plant cell and tissue culture. Ciba Foundation Symposium 137. Wiley, Chichester, p 213
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Endress, R. (1994). Plant Cells as Producers of Secondary Compounds. In: Plant Cell Biotechnology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02996-1_6
Download citation
DOI: https://doi.org/10.1007/978-3-662-02996-1_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-08165-1
Online ISBN: 978-3-662-02996-1
eBook Packages: Springer Book Archive