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Effects of Steroid Hormones in the Neonate

  • Chapter
Hormone Toxicity in the Newborn

Part of the book series: Monographs on Endocrinology ((ENDOCRINOLOGY,volume 31))

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Abstract

Estradiol, or testosterone, and a variety of C-19 and C-18 synthetic steroids with androgen- or estrogen-like biological activity given to the neonate induce sterility in the adult. Pregnanes are not active in this respect. Those competing with estrogens and androgens (progesterone) protect the neonate against the deleterious effect. These compounds are active in the neonate whether injected repeatedly or given only in one injection (Table 4.1). In most studies rodents (rats or mice) were the test animal of choice, but other mammals and even birds are sensitive.

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  1. The College of Staten Island of the City University of New York, Staten Island, New York, USA

    Fred A. Kincl Ph.D., DSc., FRSC (Professor Emeritus)

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  1. Fred A. Kincl Ph.D., DSc., FRSC
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© 1990 Springer-Verlag Berlin Heidelberg

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Kincl, F.A. (1990). Effects of Steroid Hormones in the Neonate. In: Hormone Toxicity in the Newborn. Monographs on Endocrinology, vol 31. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83794-4_4

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  • DOI: https://doi.org/10.1007/978-3-642-83794-4_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83796-8

  • Online ISBN: 978-3-642-83794-4

  • eBook Packages: Springer Book Archive

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