Hormone Toxicity in the Newborn

  • Fred A. Kincl

Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 31)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Fred A. Kincl
    Pages 1-4
  3. Fred A. Kincl
    Pages 121-167
  4. Fred A. Kincl
    Pages 168-265
  5. Fred A. Kincl
    Pages 266-287
  6. Fred A. Kincl
    Pages 288-313
  7. Fred A. Kincl
    Pages 314-319
  8. Back Matter
    Pages 320-334

About this book

Introduction

The account of "neonatal sterilization" is the story of the advocates of direct effect of steroids on the gonads and those who believed in the indirect influence, mediated through the hypothalamus and/or the pituitary gland. As often happens in biology, both convictions represent the same image seen from different perspectives. Prof DC Johnson (Kansas City, KS) reminisced the beginning of the story in a letter to me. I am paraphrasing parts of the letter with his permission. "As a starting point we could pick the life-long research of Emil Steinach ... " Steinach recognized the influence of testes on the develop­ ment of accessory sex organs in 1894, described virilization of females and feminization of males in 1913, and identified the controlling influence of the hypophysis on the gonads in 1928. He reviewed his work in a book Sex and Life, Forty Years of Biological and Medical Experience (E Steinach and L Loebe!; Faber and Faber, London, 1940). He got on the wrong road in later years and that is the reason everybody seems to have forgotten him. He presented his hypothesis that estrogen has a direct effect upon the testes, i. e. hormone antagonism, at the 1st International Congress on Sex Research in 1926.

Keywords

biosynthesis embryo estrogen receptor fetus growth growth hormone hormone hormones newborn prolactin regulation reproduction sex steroid thyroid hormone

Authors and affiliations

  • Fred A. Kincl
    • 1
  1. 1.The College of Staten Island of the City University of New YorkStaten IslandUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-83794-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-83796-8
  • Online ISBN 978-3-642-83794-4
  • Series Print ISSN 0077-1015
  • About this book