Zusammenfassung
Grundlegend neue Erkenntnisse über Cannabis und seine Inhaltsstoffe sind in den letzten Jahren nicht gewonnen worden. Deshalb ist es vielleicht ganz nützlich, aus einer gewissen zeitlichen Distanz heraus entsprechend dem Generalthema dieser Tagung „Biologie der Sucht“ und die zahlreichen Untersuchungen zur Toleranz gegen Abhängigkeit von Cannabis speziell THC kritisch zusammenzufassen und zu versuchen, eine begründete Antwort auf diese immer noch umstrittene Frage zu geben. Dabei ist zu berücksichtigen, daß es außerordentlich schwer ist, unter den vielen Einflußgrößen den pharmakodynamischen Anteil an der Suchtentstehung gegenüber Cannabis herauszuarbeiten.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
Literatur
Barbor TF, Mendelson JH, Greenberg I, Kuehnle JC (1975) Marijuana consumption and tolerance to physiological and subjective effects. Arch Gen Psychiatry 32:1548–1552
Becker HS (1968) Marihuana: A sociological overview. In: Salomon D (ed) The marihuana paper. Signet Books, New York, pp 65–102
Cohen S (1976) The 94-day cannabis study. Ann NY Acad Sci 282:211–220
Deneau GA, Kaymakcalan S (1974) Physiological and psychological dependence to synthetic delta 9-tetrahydrocannabinol (THC) in rhesus monkeys. Pharmacologist 37:23–29
Dornbush RL, Freedman AM, Fink M (eds) (1976) Chronic cannabis use. Ann NY Acad Sci, p 282
Harris RT, Waters W, McLendon D (1974) Evaluation of reinforcing capability of delta 9-tetrahydrocannabinol in rhesus monkeys. Psychopharmacologia 37:23–29
Kaymakcalan S (1973) Tolerance to and dependence on cannabis. Bull Narc 25:39–47
Lang WJ, Latiff AA, McQueen A, Singer G (1977) Self administration of nicotine with and without a food delivery schedule. Pharmacol Biochem Behav 7:65–70
Leite JR, Carlini EA (1974) Failure to obtain cannabis directed behavior and abstinence syndrome in rats chronically treated with cannabis sativa extracts. Psychopharmacologia 36:133–145
Lewis MF (1972) Marijuana today: An overview. In: Lewis MF (ed) Current research in marijuana. Academic Press, New York, pp 215–219
McKearney JW, Barrett JE (1978) Schedule-controlled behavior and the effects of drugs. In: Blackman DE, Sanger DJ (eds) Behavioral pharmacology. Plenum Press, New York London, pp 1–68
Mendelson JH, Babor TF, Kuehnle JC, Rossi AM, Bernstein JG, Mello NK, Greenberg I (1976) Behavioral and biologic aspects of marijuana use. In: Dornbush RL, Freedman AM, Fink M (eds) Chronic cannabis use. The New York Acad. of Sciences, New York, pp 186–210
Oei TPS, Singer G (1979) The effect of a fixed time schedule and body weight on ethanol self administration. Pharmacol Biochem Behav 10:767–770
Okamoto M (1977) Physical dependency characteristics of a long-acting barbiturate, barbital, compared to the short-acting pentobarbital. In: Thompson T, Unna KR (eds) Predicting dependence liability of stimulants and depressant drugs. University Park Press, Baltimore London Tokyo, pp 57–74
Peres-Reyes M, Timmons MC, Wall ME (1974) Long-term use of marihuana and the development of tolerance or sensitivity to delta 9-tetrahydrocannabinol. Arch Gen Psychiatry 31:89–91
Renault PF, Schuster CA, Freedman DX, Sikic B, Nebel de Mello D, Halaris A (1974) Repeat administration of marihuana smoke to humans. Arch Gen Psychiatry 31:95–102
Schaeffer J, Andrysiak T, Ungerleider JT (1981) Cognition and longterm use of ganja (cannabis). Science 213:465–466
Schuster CR, Thompson T (1969) Self-administration of and behavioral dependence on drugs. Ann Rev Pharmacol 9:483–502
Seevers MH, Deneau GA (1963) Physiological aspects of tolerance and physical dependence. In: Root WW, Hofman FG (eds) Physiological pharmacology. A comprehensive treatise, vol I: Nervous system — Part A: Central nervous system drugs. Academic Press, New York London, pp 565–640
Takahashi RN, Singer G (1980) Effect of body weight levels on cannabis self-injection. Pharmacol Biochem Behav 13:877–881
Weil AT, Zinberg NE, Nelson JU (1968) Clinical and psychological effects of marihuana in man. Science 162:1234–1242
Wikler A (1971) Some complications of conditioning theory for problems of drug abuse. Behav Sci 16:92–97
Wikler A (1976) Aspects of tolerance to and dependence on cannabis. Ann NY Acad Sci 282:126–147
Rights and permissions
Copyright information
© 1985 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Coper, H. (1985). Zum Abhängigkeitspotential von Cannabis. In: Biologie der Sucht. Suchtproblematik. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82542-2_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-82542-2_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-15560-7
Online ISBN: 978-3-642-82542-2
eBook Packages: Springer Book Archive