Abstract
In opening this Symposium, I thought it appropriate to reflect on some broad issues of research on DNA replication before presenting a brief review of our E. coli work on the start and elongation of chains and on the initiation and termination of chromosomes. In this overview, I will offer the briefest glimpse of the physiological features of replication on the one hand and only hints of the structure-function relationships of the numerous proteins and enzymes and DNA on the other.
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© 1992 Springer-Verlag Berlin Heidelberg
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Kornberg, A. (1992). Regulation of Initiation of Chromosome Replication. In: Hughes, P., Fanning, E., Kohiyama, M. (eds) DNA Replication: The Regulatory Mechanisms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76988-7_1
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DOI: https://doi.org/10.1007/978-3-642-76988-7_1
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