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GABA-Immunoreactive Structures in Rat Kidney

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GABA Outside the CNS

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Abstract

A large body of evidence obtained from biochemical and pharmacological studies shows that each element of the γ-aminobutyric acid (GABA)ergic system is present in the mammalian kidney. The GABA content in the kidney of several species, including humans, was found to be as high as 1/20-1/5 of that in brain [3]. The activity of the GABA synthesizing enzyme in kidney is about 1/6 that of the brain glutamic acid decarboxylase (GAD) [3]. Moreover, the kidney exhibits nearly half as high an activity of GABA transaminase (GABA-T) as the brain does [26].

This study was supported by the Deutsche Forschungsgemeinschaft (Wo 279/6-5 and 8-3).

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Authors
  1. E. Dobó
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  2. Á. Párducz
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  3. J. R. Wolff
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  4. S. L. Erdö
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Editor information

Editors and Affiliations

  1. Department of Anatomy, University of Göttingen, Kreuzbergring 36, W-3400, Göttingen, Germany

    Sándor L. Erdö Ph.D.

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© 1992 Springer-Verlag Berlin Heidelberg

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Dobó, E., Párducz, Á., Wolff, J.R., Erdö, S.L. (1992). GABA-Immunoreactive Structures in Rat Kidney. In: Erdö, S.L. (eds) GABA Outside the CNS. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76915-3_11

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  • DOI: https://doi.org/10.1007/978-3-642-76915-3_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76917-7

  • Online ISBN: 978-3-642-76915-3

  • eBook Packages: Springer Book Archive

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