Zusammenfassung
Unter perioperativer Strahlentherapie des Rektumkarzinoms ist die präoperative oder postoperative Radiotherapie der primär im Gesunden resektablen Karzinome (R0) bzw. der primär nicht radikal operablen Karzinome (R1 und R2) zu verstehen. Sie stellt also (mit und ohne zusätzliche Chemotherapie) eine adjuvante Maßnahme zur Operation dar, welche nach wie vor als primäre Therapie der Wahl gilt. Die Rate an Lokalrezidiven soll gesenkt und die Dauer des rezidivfreien bzw. gesamten Überlebens verlängert werden.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Balslev IB, Pedersen M, Teglbjaerg PS et al. (1986) Postoperative radiotherapy in Dukes B and C carcinoma of the rectum and rectosigmoid. A randomized multicenter study. Cancer 58: 22–28
Boulis-Wassif S, Gerard A, Loygue J et al. (1984) Final results of a randomized trial on the treatment on rectal cancer with preoperative radiotherapy alone or in combination with 5-FU, followed by radical surgery. Cancer 53: 1811–1818
Boulis-Wassif S, Langenhorst BL, Hop WCJ (1979) The contribution of preoperative radiotherapy in the management of borderline operability rectal cancer. In: Salmon SE, Jones SE (ed) Adjuvant therapy of cancer II. Grune and Stratton, New York, pp 612–620
Duncan W (1987) Preoperative radiotherapy in rectal cancer. World J Surg 11: 439–445
Fisher B, Wolmark N, Rockette H et al. (1988) Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP Protocol R-01. J Natl Cancer Inst 80: 21–29
Gall FP, Scheele J (1986) Maligne Tumoren des Rektums. In: Gall FP, Hermanek P, Tonak J (ed) Chirurgische Onkologie. Springer, Berlin Heidelberg New York London Paris Tokyo 520–580
Galloway DJ, Cohen AM, Shank B, Friedman MA (1989) Adjuvant multimodality treatment of rectal cancer. Br J Surg 76: 440–447
Gastrointestinal Tumor Study Group (1986) Survival after postoperative combination treatment of rectal cancer. N Engl J Med 315: 1294–1295
Gerard A, Buyse M, Nordlinger B et al. (1988) Preoperative radiotherapy as adjuvant treatment in rectal cancer: Final results of a randomized study of the European Organization for Research and Treatment of Cancer ( EORTC ). Ann Surg 208: 606–614
Gunderson LL, Collins R, Earle JD et al. (1986) Adjuvant treatment of rectal cancer: Randomized prospective study of irradiation plus minus chemotherapy-an NCCTG, Mayo Clinic study. Int J Radiat Oncol Biol Phys 12: 169
Hermanek P (1989) Persönliche Mitteilungen
Higgins GA, Conn JH, Jordan JH et al. (1975) Preoperative radiotherapy for colorectal cancer. Ann Surg 181: 624–631
Higgins GA, Humphrey EW, Dwight RW et al. (1986) Preoperative radiation and surgery for cancer of the rectum. Cancer 58: 352–359
Hoskins RB, Gunderson LL, Dosoretz DE, Rich TA, Galdibini J, Donaldson G, Cohen AM (1985) Adjuvant postoperative radiotherapy in carcinoma of the rectum and rectosigmoid. Cancer 55: 61–71
Kopelson G (1983) Adjuvant postoperative radiation therapy for colorectal carcinoma above the peritoneal reflection. Cancer 52: 633–636
Mendenhall WM, Million RR, Pfaff WW (1983) Patterns of recurrence in adenocarcinoma of the rectum and rectosigmoid treated with surgery alone: Implications in treatment planning with adjuvant radiation therapy. Int J Radiat Oncol Biol Phys 9: 977–985
Minsky BD, Mies C, Recht A et al. (1988) Resectable adenocarcinoma of the rectum and rectosigmoid. Cancer 61: 1408–1416
Pilipshen SJ, Heilweil M, Quan SHQ, Sternberg SS, Enker WE (1984) Patterns of pelvic recurrence following definitive resection of rectal cancer. Cancer 52: 1354–1362
Rich T, Gunderson LL, Lew R, Galdibini JJ, Cohen AM, Donaldson G (1984) Patterns of recurrence of rectal cancer after potentially curative surgery. Cancer 52: 1317–1329
Rider WD, Palmer JA, Mahoney LJ, Robertson CT (1977) Preoperative irradiation in operable cancer of the rectum: report on the Toronto trial. Can J Surg 20: 335–338
Schild SE, Martenson JA, Gunderson LL et al. (1989) Postoperative adjuvant therapy of rectal cancer: An analysis of disease control, survival and prognostic factors. Int J Radiat Oncol Biol Phys 17: 55–62
Sparso BH, Von der Maase H, Kristensen D, Christiansen D, Damgaard-Nielsen SA, Hebjorn N, Andersen B (1984) Complications following postoperative combined radiation and chemotherapy in adenocarcinoma of the rectum and rectosigmoid: A randomized trial that failed. Cancer 54: 2363–2366
Stockholm Rectal Cancer Study Group (1987) Short term preoperative radiotherapy for adenocarcinoma of the rectum. Am J Clin Oncol 10: 369–375
Tepper JE, Cohen AM, Wood WC, Orlow EL, Hedberg SE (1987) Postoperative radiation therapy of rectal cancer. Int J Radiat Oncol Biol Phys 13: 5–10
Vigliotti A, Rich TA, Romsdahl MM, Withers HR, Oswald MJ (1987) Postoperative adjuvant radiotherapy for adenocarcinoma of the rectum and rectosigmoid. Int J Radiat Oncol Biol Phys 13: 999–1006
Walz BJ, Grenn MR, Lindstorm ER, Butcher HR (1981) Anatomical prognostic factors after abdominal perineal resection. Int J Radiat Oncol Biol Phys 7: 477–484
Zucali R, Gardani G, Lattuada A (1987) Adjuvant irradiation after radical surgery of cancer of the rectum and rectosigmoid. Radiother Oncol 8: 19–24
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Sauer, R., Grabenbauer, G. (1992). Perioperative Strahlentherapie beim Rektumkarzinom. In: Schmoll, HJ., Meyer, HJ., Wilke, H., Pichlmayr, R. (eds) Aktuelle Therapie gastrointestinaler Tumoren. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76187-4_28
Download citation
DOI: https://doi.org/10.1007/978-3-642-76187-4_28
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-76188-1
Online ISBN: 978-3-642-76187-4
eBook Packages: Springer Book Archive