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Biochemical Characterization of the Nerve Growth Factor Receptor in Neural-Related Tumors

  • Chapter
Neuronal Growth Factors

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 165))

Abstract

Neurotrophic factors are required for regulation of cell division, cell death, axon outgrowth and synapse formation during fetal development, maintenance of the adult nervous system, and neural regeneration following injury. Due to the relative abundance of nerve growth factor (NGF) in the murine salivary gland, NGF was the first neurotrophic factor to be isolated and characterized (Levi-Montalcini 1987).

This investigation was supported by USPHS grants NS-21716 and CA-47983 and by the National Neurofibromatosis Foundation

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Author information

Authors and Affiliations

  1. The Worcester Foundation for Experimental Biology, Shrewsbury, MA, 01545, USA

    A. H. Ross

  2. Division of Neurology, Aichi Medical University, Nagakute, Aichi, 480-11, Japan

    G. Sobue

  3. Department of Microbiology, Kobe University School of Medicine, Kobe 650, Japan

    H. Hotta

  4. Department of Neurology, The Childrens’ Hospital of Philadelphia, Philadelphia, PA, 19104, USA

    U. R. Reddy

Authors
  1. A. H. Ross
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  2. G. Sobue
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  3. H. Hotta
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  4. U. R. Reddy
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Editor information

Editors and Affiliations

  1. Department of Physiology and Biophysics, University of Washington, 98195, Seattle, WA, USA

    Mark Bothwell MD

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© 1991 Springer-Verlag Berlin · Heidelberg

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Ross, A.H., Sobue, G., Hotta, H., Reddy, U.R. (1991). Biochemical Characterization of the Nerve Growth Factor Receptor in Neural-Related Tumors. In: Bothwell, M. (eds) Neuronal Growth Factors. Current Topics in Microbiology and Immunology, vol 165. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75747-1_2

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  • DOI: https://doi.org/10.1007/978-3-642-75747-1_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75749-5

  • Online ISBN: 978-3-642-75747-1

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