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Immune Interactions with Islet Cells: Implications for the Pathogenesis of Insulin-Dependent Diabetes Mellitus

  • Chapter
The Pathology of the Endocrine Pancreas in Diabetes

Abstract

Occasionally a single scientific paper may signal a new era in the study of a disease. The 1965 paper by Willy Gepts was such a signal [1]. The (re)discovery of insulitis provided the impetus for new thoughts about the pathogenesis of insulin-dependent diabetes mellitus (IDDM) and for the emergence of a new research field: immunology of IDDM.

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Authors
  1. J. Nerup
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  2. T. Mandrup-PouIsen
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  3. J. Mølvig
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  4. G. Spinas
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Editor information

Editors and Affiliations

  1. Division of Diabetes, Nutrition and Metabolic Disorders Department of Medicine, Centre Hospitalier Universitaire du Sart-Tilman, B-4000, Liège 1, Belgium

    Pierre J. Lefèbvre

  2. Dept. of Metabolism and Endocrinology, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090, Brussels, Belgium

    Daniel G. Pipeleers

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© 1988 Springer-Verlag Berlin Heidelberg

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Nerup, J., Mandrup-PouIsen, T., Mølvig, J., Spinas, G. (1988). Immune Interactions with Islet Cells: Implications for the Pathogenesis of Insulin-Dependent Diabetes Mellitus. In: Lefèbvre, P.J., Pipeleers, D.G. (eds) The Pathology of the Endocrine Pancreas in Diabetes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72691-0_5

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  • DOI: https://doi.org/10.1007/978-3-642-72691-0_5

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