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Fetal Development of Male and Female Genital Tract, Mouse

  • Chapter
Genital System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

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Abstract

In mammals the sex of an individual is established during fertilization of the oocyte. Yet, during fetal development an indifferent anlage of the genital tract is formed initially. Later on male and female sex organs are differentiated from the organ primordia present in this indifferent stage. In the present chapter we will first briefly review the sequence of events occurring during determination of mammalian sex. The main focus, however, will be on the dichotomy of development of the male and female genital tract from the indifferent anlage. These considerations will be supplemented by a discussion of the genetic mutants “testicular feminization” (Tfm) and “sex reversal” (Sxr) in which sexual development deviates from normal.

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Authors
  1. K.-U. Thiedemann
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Editors and Affiliations

  1. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, 01772, Southborough, MA, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) & Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology, Emeritus) &  (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Federal Republic of Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1987 Springer-Verlag Berlin Heidelberg

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Thiedemann, KU. (1987). Fetal Development of Male and Female Genital Tract, Mouse. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Genital System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72550-0_9

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  • DOI: https://doi.org/10.1007/978-3-642-72550-0_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72552-4

  • Online ISBN: 978-3-642-72550-0

  • eBook Packages: Springer Book Archive

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