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Sequence Comparison Among Arenaviruses

  • Conference paper
Arenaviruses

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 133))

Abstract

Contemporary techniques for DNA cloning and rapid nucleotide sequencing have made significant contributions to the present understanding of gene structure and regulation (see, for example, Gluzman and Shenk 1983; Gluzman 1985). Cloning has allowed the amplification of genetic material that may be difficult or impossible to propagate by conventional tissue culture methods (e. g., hepatitis B virus and several papillomaviruses) and provides unlimited material for hybridization probes and nucleotide sequencing. Information derived from sequencing has identified primary gene structures, amino acid sequences for protein coding regions, and regulatory signals that appear to be widespread in eukaryotic genomes (Gilbert 1981; SAnger 1981). Knowledge of a nucleotide sequence does not automatically provide answers to all outstanding questions, but the information does represent useful progress towards such answers.

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Author information

Authors and Affiliations

  1. Department of Immunology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, La Jolla, CA, 92037, USA

    P. J. Southern

  2. NERC Institute of Virology, Mansfield Road, Oxford, OX1 3SR, UK

    D. H. L. Bishop

Authors
  1. P. J. Southern
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  2. D. H. L. Bishop
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Editor information

Editors and Affiliations

  1. Department of Immunology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, La Jolla, California, 92037, USA

    Michael B. A. Oldstone M.D.

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© 1987 Springer-Verlag Berlin · Heidelberg

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Southern, P.J., Bishop, D.H.L. (1987). Sequence Comparison Among Arenaviruses. In: Oldstone, M.B.A. (eds) Arenaviruses. Current Topics in Microbiology and Immunology, vol 133. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71683-6_3

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  • DOI: https://doi.org/10.1007/978-3-642-71683-6_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71685-0

  • Online ISBN: 978-3-642-71683-6

  • eBook Packages: Springer Book Archive

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