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Congenital Neuroblastoma

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Renal and Adrenal Tumors

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Abstract

Neuroblastoma sympathicum represents 10%–15% of all malignant tumors in children. The annual incidence is estimated at 9 per million children under 15 years of age [9]. Although its appearance is scattered throughout childhood, diagnosis is made within the first 12 months of life in one-third of patients and in the 2nd and 3rd years of life in another one-third (Fig. 1).

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References

  1. Altman AJ, Baehner RL (1976) Favorable prognosis for survival in children with coincident opsomyoclonus and neuroblastoma. Cancer 37: 846

    Article  PubMed  CAS  Google Scholar 

  2. Anders D, Frick R, Kindermann G (1970) Metastasierendes Neuroblastom des Feten mit Aussaat in die Pla-centa. Geburtshilfe Frauenheilkd 30: 969

    PubMed  CAS  Google Scholar 

  3. Angerpointner TA (1985) Ein Fall von geburtstraumatisch rupturiertem, kongenitalem Neuroblastom. Monatsschr Kinderheilkd 133: 241

    PubMed  CAS  Google Scholar 

  4. Arenson EB, Hutter JJ Jr, Restuccia RD, Holton CHP (1976) Neuroblastoma in father and son. JAMA 236: 727

    Article  Google Scholar 

  5. Bachmann K-D (1962) Das Neuroblastoma sympathicum. Klinik und Prognose von 1030 Fallen. Z Kinderheilkd 86: 710

    Article  PubMed  CAS  Google Scholar 

  6. Bachmann K-D, Kröll W (1968) Über das praenatal entstandene Neuroblastom sympathicum. Z Kinderheilkd 103: 61

    Article  PubMed  CAS  Google Scholar 

  7. Bachmann KD (1971) Tumoren des sympathischen Nervensystems. In: Opitz H, Schmid F (eds) Handbuch der Kinderheilkunde (2nd ed.) Vol. 8: 328 Springer, Berlin Heidelberg New York

    Google Scholar 

  8. Beckwith J, Perrin E (1963) In situ neuroblastomas; a contribution to the natural history of neural crest tumors. Am J Pathol 43: 1089

    PubMed  CAS  Google Scholar 

  9. Berthold F (1985) Current concepts on the biology of neuroblastoma. Blut 50: 65

    Article  PubMed  CAS  Google Scholar 

  10. Bill AH, Morgan A (1970) Evidence of immune reactions to neuroblastoma and future possibilities for investigation. J Pediatr Surg 5: 111

    Article  PubMed  CAS  Google Scholar 

  11. Boyd W (1957) The spontaneous regression of cancer. J Can Assoc Radiol 8: 45

    Google Scholar 

  12. Brock CE, Ricketts RR (1982) Hemoperitoneum from spontaneous rupture of neonatal neuroblastoma. Am J Dis Child 136: 370

    PubMed  CAS  Google Scholar 

  13. Chatten J, Voorhess ML (1967) Familial neuroblastoma. N Engl J Med 277: 1230

    Article  PubMed  CAS  Google Scholar 

  14. Cochran W (1963) Neuroblastoma (sympathicoblastoma) in Northern Ireland: a review over a ten-year period. Ulster Med J 32: 82

    PubMed  CAS  Google Scholar 

  15. D’Angio GJ, Evans AE, Koop CE (1971) Special pattern of widespread neuroblastoma with a favourable prognosis. Lancet 1: 1046

    Article  PubMed  Google Scholar 

  16. Delalieux C, Ebinger G, Maurus R, Sliwowski H (1975) Myoclonic encephalopathy and neuroblastoma. N Engl J Med 292: 46

    Article  PubMed  CAS  Google Scholar 

  17. De Lorimier AD, Bragg KU, Linden G (1969) Neuroblastoma in childhood. Am J Dis Child 118: 441

    Google Scholar 

  18. Dodge HJ, Benner MC (1945) Neuroblastoma of adrenal medulla in siblings. Rocky Mt Med J 42: cited according to 13

    Google Scholar 

  19. Dresler St, Harvey DG, Levisohn PM (1979) Retroperi-toneal Neuroblastoma widely metastatic to the central nervous system. Ann Neurol 5: 196

    Article  PubMed  CAS  Google Scholar 

  20. Drukker A (1965) Neuroblastoma. Report of 3 cases with long-term survival. Acta Paedr Scand 54: 397

    Article  CAS  Google Scholar 

  21. Dziedzic S, Dziedzic L, Gitlow S (1973) Separation and determination of urinary homovanillic acid and iso-homovanillic acid by gas-liquid chromatography and electron capture detection. J Lab Clin Med 82: 829

    PubMed  CAS  Google Scholar 

  22. Evans AE (1977) Immunotherapy of neuroblastoma. Ninth meeting int. society paediatr. oncol (SIOP) Philadelphia, 20–24 September

    Google Scholar 

  23. Evans AE, Hummeler K (1973) The significance of primitive cells in marrow aspirates of children with neuro-blastoma. Cancer 32: 906

    Article  PubMed  CAS  Google Scholar 

  24. Evans AE, D’Angio GJ, Randolph J (1971) A proposed staging for children with neuroblastoma. Cancer 27: 374

    Article  PubMed  CAS  Google Scholar 

  25. Fasanotti A (1948) Contributo albo studio dei tumori immaturi del simpatico. Pediatria 56: 503

    CAS  Google Scholar 

  26. Finkelstein JZ (1976) Neuroblastoma: a unique solid tumor of childhood. In: Donaldson M, Seydel HG (eds) Trends in childhood cancer. Wiley, New York

    Google Scholar 

  27. Griffin ME, Bolande RP (1969) Familial neuroblastoma regression and maturation of ganglioneuroflbroma. Pediatrics 43: 377

    PubMed  CAS  Google Scholar 

  28. Grotting JC, Kassel St, Dehner LP (1979) Nesidioblastosis and congenital neuroblastoma. Arch Pathol Lab Med 103: 642

    PubMed  CAS  Google Scholar 

  29. Haden MA, Keats TE (1983) Congenital intraspinal neuroblastoma with intraspinal calcification in the neo-natal period: report of a case with a 32-year follow up. Pediatr Radiol 13: 335

    Article  PubMed  CAS  Google Scholar 

  30. Hagstrom J (1930) Fetal dystocia due to metastatic neuroblastoma of the liver. Am J Obstet Gynecol 19: 673

    Google Scholar 

  31. Hardy PC, Nesbit MF (1972) Familial neuroblastoma: report of a kindred with a high incidence of infantile tumors. J Pediatr 80: 74

    Article  PubMed  CAS  Google Scholar 

  32. Harms D, Wilke H (1977) Pathologische Anatomie des Neuroblastoms. Z Kinderchirurg 22: 122

    Google Scholar 

  33. Harvey F, Tennant R (1934) Primary neurogenic sarcoma of bladder. Am J Pathol 10: 125

    PubMed  CAS  Google Scholar 

  34. Hawthorne HC, Nelsen JS, Witzleben CL, Giangiacomo J (1970) Blanching subcutaneous nodules in neonatal neuroblastoma. J Pediatr 77: 297

    Article  PubMed  Google Scholar 

  35. Hellstrom I, Hellstrom KE, Bill AH, Pierce GE, Young JPS (1970) Studies on cellular immunity to human neu-roblastoma cells. Int J Cancer 6: 172

    Article  PubMed  CAS  Google Scholar 

  36. Holschneider AM, Geiger H, Bolkenius N, Janka G, Lampert F (1977) Spatfolgen beim Neuroblastoma: Paraneoplastische Erkrankungen und Therapiefolgen. Monatsschr Kinderheilkd 125: 69

    PubMed  CAS  Google Scholar 

  37. Hrabovsky E, Jones B (1979) Congenital intraspinal neuroblastoma. Am J Dis Child 133: 73

    PubMed  CAS  Google Scholar 

  38. Hughes M, Mardsen HB, Palmer MK (1974) Histologic patterns of neuroblastoma related to prognosis and clinical staging. Cancer 34: 1706

    Article  PubMed  CAS  Google Scholar 

  39. Ikeda Y, Lister J, Bouton JM (1981) Congenital neuro-blastoma, neuroblastoma “in situ” and the normal fetal development of the adrenal. J Pediatr Surg 16: 636 238 K.-D. Bachmann and H.Chr. Dominick

    Article  PubMed  CAS  Google Scholar 

  40. Janetschek G, Weitzel D, Stein W, Müntefering H, Aiken P (1984) Prenatal diagnosis of neuroblastoma by sonography. Urology 24: 397

    Article  PubMed  CAS  Google Scholar 

  41. Klein H, Plöchl E (1974) Familiäres Neuroblastom der Nebennieren beim Neugeborenen. Miinch Med Wochenschr 116: 1163

    CAS  Google Scholar 

  42. Knudson AG Jr, Meadows AT (1976) Developmental genetics of neuroblastoma. JNCI 57 (3): 675

    PubMed  Google Scholar 

  43. Koop CE, Johnson DG (1971) Neuroblastoma: an assessment of therapy in reference of staging. J Pediatr Surg 6: 515

    Google Scholar 

  44. Kushner B, Helson L (1985) Monozygotic siblings discordant for neuroblastoma. Etiologic implications. J Pediatr 107: 405

    Article  PubMed  CAS  Google Scholar 

  45. Lampert F (1984) Neuroblastom. In: Kornhuber B (ed) Onkologie Pediatric: Weiter- und Fortbildung. Springer, Berlin Heidelberg New York

    Google Scholar 

  46. Lampert F, Dietmair E (1973) Leukozyten-Adharenz-Inhibition: Ein einfacher in vitro-Test zum Nachweis tumorspezifischer Immunitat und blockierender Serumfaktoren bei Kindern mit Malign omen. Infection 1: 17

    Article  PubMed  CAS  Google Scholar 

  47. Lee J AH (1967) Summer and death from neuroblastoma. Br Med J 11: 404

    Article  Google Scholar 

  48. Lipinski C, Kratzer W, Daum R (1975) Die infantile myoklonische Encephalopathie — ein paraneoplastisches Syndrom bei Neuroblastom. Z Kinderchirurg 16: 111

    Google Scholar 

  49. Lopez-Ibor B, Schwartz AD (1985) Neuroblastoma. Pediat Clin North Am 32: 755

    CAS  Google Scholar 

  50. Martin RF, Beckwith JB (1968) Lymphoid infiltrates in neuroblastomas: their occurrence and prognostic sig-nificance. J Pediatr Surg 3: 161

    Article  PubMed  CAS  Google Scholar 

  51. Moss ThJ, Kaplan L (1978) Association of hydrops fetalis with congenital neuroblastoma. Am J Obstet Gynecol 132: 905

    PubMed  CAS  Google Scholar 

  52. Murthy TVM, Irving IM, Lister J (1978) Massive adrenal hemorrhage in neonatal neuroblastoma. J Pediatr Surg 13: 31

    Article  PubMed  CAS  Google Scholar 

  53. Newton ER, Louis F, Dalton ME, Feingold M (1985) Fetal neuroblastoma and catecholamine-induced maternal hypertension. Obstet Gynecol 65 [Suppl 3]: 49S

    PubMed  CAS  Google Scholar 

  54. Pinkel D, Pratt C, Holton C, James D, Wrenn E, Hustu O (1968) Survival of children with neuroblastoma treated with combination chemotherapy. J Pediatr 73: 928

    Article  PubMed  CAS  Google Scholar 

  55. Potter EL, Parrish JM (1942) Neuroblastoma, ganglioneuroma and fibroneuroma in a stillborn fetus. Am J Pathol 18: 141

    PubMed  CAS  Google Scholar 

  56. Roberts KB, Freemann JM (1975) Cellular ataxia and “occult neuroblastoma” without opsoclonus. Pediatrics 56: 464

    PubMed  CAS  Google Scholar 

  57. Rosta J, Gorcas L (1959) Malignant orbital tumor in a young infant. Ann Pediatr 193: 304

    CAS  Google Scholar 

  58. Rudiger HW (1978) Genetisch bedingte Risikofaktoren fur maligne Tumoren beim Menschen. Dtsch Med Wochenschr 103: 77

    Article  PubMed  CAS  Google Scholar 

  59. Rupprecht L, Mortier W (1975) Cerebelläre Bewegungsstörung und Neuroblastom. Monatsschr Kinderheilkd 123: 392

    PubMed  CAS  Google Scholar 

  60. Schwartz AD, Dadashzadeh M, Lee H, Swaney JJ (1974) Spontaneous regression of disseminated neuroblastoma. J Pediatr 85: 760

    Article  PubMed  CAS  Google Scholar 

  61. Senelick RC, Bay PF, Lahey ME (1973) Neuroblastoma and myoclonic encephalopathy: two cases and a review of the literature. J Pediatr Surg 8: 623

    Article  PubMed  CAS  Google Scholar 

  62. Smith J (1951) Case of ganglio-sympathicoblastoma of the testis in an infant. Br J Urol 23: 39

    Article  PubMed  CAS  Google Scholar 

  63. Sober J, Hirsch M (1965) Unilateral massive adrenal hemorrhage in newborn infant. J Urol 93: 430

    PubMed  CAS  Google Scholar 

  64. Stadler HE, Worley RH (1955) Neuroblastomatosis in one of monozygotic twins. J Pediatr 47: 485

    Article  PubMed  CAS  Google Scholar 

  65. Stewart FN, Copeland MM (1931) Neurogenic sarcoma. Am J Cancer 15: 1235

    Google Scholar 

  66. Strauss L, Driscoll SG (1964) Congenital neuroblastoma involving the placenta. Report of two cases. Pediatrics 34: 23

    PubMed  CAS  Google Scholar 

  67. Turkel SG, Itabashi HH (1974) The natural history of neuroblastic cells in the fetal adrenal gland. Am J Pathol 76: 225

    PubMed  CAS  Google Scholar 

  68. Ullrich R (1970) Sympathicogoniome and Vererblichkeit maligner Geschwülste. Schweiz Med Wochenschr 100: 749

    PubMed  CAS  Google Scholar 

  69. van der Slikke JW, Balk AG (1980) Hydramnios with hydrops fetalis and disseminated fetal neuroblastoma. Obstet Gynecol 55: 250

    PubMed  Google Scholar 

  70. Vigorelli L (1962) Multiple subcutaneous sympathoblastoma with favorable evolution. Minerva Pediatr 14: 1219

    PubMed  CAS  Google Scholar 

  71. Voute PA, Wadmann SK, van Putten WJ (1970) Congenital neuroblastoma symptoms in the mother during pregnancy. Clin Pediatr 9: 206

    Article  Google Scholar 

  72. Voute PA, van Putten WJ, Burgers JMV (1975) Tumors of the sympathetic nervous system. In: Bloom HJG, Lemerle L, Neidhard MK, Voute PA (eds) Cancer in children. Springer, Berlin Heidelberg New York

    Google Scholar 

  73. Wagget J, Aherae G, Aherne W (1973) Familial neuroblastoma: report of two sib pairs. Arch Dis Child 48: 63

    Article  PubMed  CAS  Google Scholar 

  74. Weinberg T, Radman R (1943) Fetal dystocia due to neuroblastoma of adrenal with metastases to liver. Am J Obstet Gynecol 46: 440

    Google Scholar 

  75. Wong KY, Hanenson SB, Lampkin BC (1971) Familial neuroblastoma. Am J Dis Child 121: 415 Congenital Neuroblastoma 239

    PubMed  CAS  Google Scholar 

  76. Zimmermann J (1951) Ganglioneuroblastome als erbliche Systernerkrankung des Sympathicus. Beitr Pathol Anatol 111: 335

    Google Scholar 

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Authors
  1. K.-D. Bachmann
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  2. H. Chr. Dominick
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Editors and Affiliations

  1. Röntgendiagnostisches Zentralinstitut, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Eberhard Löhr

  2. Institut für Pathologie, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Lutz-Dietrich Leder

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© 1987 Springer-Verlag Berlin Heidelberg

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Bachmann, KD., Dominick, H.C. (1987). Congenital Neuroblastoma. In: Löhr, E., Leder, LD. (eds) Renal and Adrenal Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71207-4_13

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  • DOI: https://doi.org/10.1007/978-3-642-71207-4_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71209-8

  • Online ISBN: 978-3-642-71207-4

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