Abstract
Acquired immunodeficiency syndrome (AIDS) is a relatively new syndrome of high mortality and morbidity that has been seen in large cities since 1979, predominantly among homosexuals, intravenous drug users, Haitians, and patients with hemophilia. AIDS patients always have evidence of defective cellular immunity, including lymphopenia and grossly decreased ratios of helper to suppressor T cells. Cutaneous anergy and diminished proliferative responses to mitogens and specific antigens are also often observed. Neutrophil function appears normal, and immunoglobulin levels are usually normal or elevated. Epidemiological studies have recently suggested that one or another variant form of human T4 lymphotropic retrovirus (e.g., LAV or HTLV-III) may be responsible for the secondary, very severe immunodeficiency seen at least among the homosexual AIDS patients [6].
This study was supported in part by NIH grants CA-08748, CA-22507, CA-34995, and CA-37888
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Pollack, M.S. et al. (1984). Classical and AIDS Kaposi’s Sarcoma. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_129
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DOI: https://doi.org/10.1007/978-3-642-69770-8_129
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