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The Growth and Differentiation of Human Endothelial Cells

  • Conference paper
Hormonally Defined Media

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

  • 79 Accesses

Abstract

The non-thrombogenic nature of veins, arteries and capillaries is maintained in vivo by the presence of the endothelial cell. It has been widely recognized that the identification of factors which influence the growth and differentiation of the endothelial cell will significantly contribute to a better understanding of normal and pathological events in human biology in which the vascular tree has a major impact. These events include tumor growth, atherosclerosis, wound healing, thrombosis and hemostasis. Unfortunately, endothelial cells of human origin have been difficult to study because of their low mitotic index in vivo (1,2). In spite of these difficulties, efficatious methods have been developed for the isolation and propagation of endothelial cells in vitro (3,4,5,6 and 7).

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Author information

Authors and Affiliations

  1. Department of Pathology, Charles A. Dana Research Institute, Harvard-Thorndike Laboratory, Harvard Medical School, Beth Israel Hospital, Boston, MA, 02215, USA

    T. Maciag

  2. Department of Medicine, Charles A. Dana Research Institute, Harvard-Thorndike Laboratory, Harvard Medical School, Beth Israel Hospital, Boston, MA, 02215, USA

    R. Weinstein

Authors
  1. T. Maciag
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  2. R. Weinstein
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Editor information

Editors and Affiliations

  1. Institut für Neurobiologie, Universität Heidelberg, Im Neuenheimer Feld 504, 6900, Heidelberg 1, Germany

    G. Fischer

  2. Institut für Pharmakologie, Universität Mainz, Obere Zahlbacher Str. 67, 6500, Mainz, Germany

    R. J. Wieser

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© 1983 Springer-Verlag Berlin Heidelberg

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Maciag, T., Weinstein, R. (1983). The Growth and Differentiation of Human Endothelial Cells. In: Fischer, G., Wieser, R.J. (eds) Hormonally Defined Media. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69290-1_7

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  • DOI: https://doi.org/10.1007/978-3-642-69290-1_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69292-5

  • Online ISBN: 978-3-642-69290-1

  • eBook Packages: Springer Book Archive

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