Abstract
The molecular constituents most directly determining the structure and function of cells are the proteins, the end products of the expression of the cell’s genetic information. Synthesis of all proteins probably occurs by a process in which ribosomes catalyze the polymerization of amino acids in an alignment determined by the sequence of nucleotides in a nucleic acid template. The initial polypeptide produced is often modified by removal of a peptide fragment, methylation, acetylation, glycosylation, and/or phosphorylation to attain its final functional state. In situations where a protein is destined to pass across a membrane, the protein is often synthesized with a hydrophobic N-terminal region that is discarded after the protein has traversed the membrane. This chapter is concerned with the synthesis of the primary peptide product and focuses on the mechanisms used by the cell to accomplish this synthesis. The processes by which the production of different protein species might be controlled is also briefly considered (see Chapter 4 for post-translational modifications).
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Marcus, A. (1982). Ribosomes, Polysomes and the Translation Process. In: Boulter, D., Parthier, B. (eds) Nucleic Acids and Proteins in Plants I. Encyclopedia of Plant Physiology, vol 14 / A. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68237-7_4
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DOI: https://doi.org/10.1007/978-3-642-68237-7_4
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