Serum Inhibitors of Granulocyte CFU-C in Aplastic Anaemia

  • A. J. Barrett
  • A. Faille
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 24)


Aplastic anaemia is characterised by pancytopenia with profound bone marrow hypoplasia. This is associated with a reduced number of granulocyte precursor cells (CFU-C) in the bone marrow [6, 2]. While the end-result of a variety of processes may produce this apparent stem cell failure in aplastic anaemia, an immunological mechanism may be responsible in at least some patients [3, 1, 5].


Aplastic Anaemia Colony Growth Normal Bone Marrow Autologous Serum Mixed Lymphocyte Culture 
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© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • A. J. Barrett
  • A. Faille

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