Pathogenesis of Severe Aplastic Anemia: Inferences from Therapeutic Trials

  • B. M. Camitta
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 24)


The pathogenesis of severe aplastic anemia is not known. Therapeutic approaches have usually involved uncontrolled empiric trials of various stimulants of hematopoiesis. Recently, a prospective controlled trial evaluated the efficacy of androgens and bone marrow transplantation for treatment of severe marrow aplasia [3, 4]. Results of this study may permit limited inferences as to the pathogenesis of bone marrow failure.


Aplastic Anemia Cooperative Study Bone Marrow Failure Severe Aplastic Anemia Marrow Graft 
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© Springer-Verlag Berlin Heidelberg 1979

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  • B. M. Camitta

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