Abstract
The pathogenesis of severe aplastic anemia is not known. Therapeutic approaches have usually involved uncontrolled empiric trials of various stimulants of hematopoiesis. Recently, a prospective controlled trial evaluated the efficacy of androgens and bone marrow transplantation for treatment of severe marrow aplasia [3, 4]. Results of this study may permit limited inferences as to the pathogenesis of bone marrow failure.
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References
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Camitta, B.M. (1979). Pathogenesis of Severe Aplastic Anemia: Inferences from Therapeutic Trials. In: Heimpel, H., Gordon-Smith, E.C., Heit, W., Kubanek, B. (eds) Aplastic Anemia. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67483-9_21
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DOI: https://doi.org/10.1007/978-3-642-67483-9_21
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