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Tumor-Associated Antigens in Bronchogenic Carcinoma

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Immunodiagnosis and Immunotherapy of Malignant Tumors

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Abstract

In recent years several proteins, often associated with fetal growth, have been recognized in tumor tissues, serum, and other body fluids of patients with certain malignancies. GOLD and FREEDMAN described the carcinoembryonic antigen (CEA) (5), which was first thought to be specific for colonic cancer, and ABELEV and TATARINOW classified the alpha-1 fetoprotein (AFP) (1, 14) as a carcinofetal antigen associated with hepatoma. The antigens, however, together with other serum proteins, for example, ferritin (9), nonspecific crossreacting antigen (NCA) (8), and the pregnancy-associated α2-glycoprotein (α2-PAG) (3) are also detectable in a variety of other neoplasias.

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Author information

Authors and Affiliations

  1. Medizinische Universitätsklinik, D-3550, Marburg, Germany

    K. Havemann, C. Gropp, F.-G. Lehmann, P. Preisser & S. von Kleist

Authors
  1. K. Havemann
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  2. C. Gropp
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  3. F.-G. Lehmann
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  4. P. Preisser
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  5. S. von Kleist
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Editor information

Editors and Affiliations

  1. Abteilung Mikrobiologie, Laborbereich Immunologie, Universität Ulm, Oberer Eselsberg, D-7900, Ulm, Germany

    Hans-Dieter Flad

  2. Allgemeine Chirurgie, Universität Ulm, Steinhövelstraße 9, D-7900, Ulm, Germany

    Christian Herfarth  & Michael Betzler  & 

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© 1979 Springer-Verlag Berlin Heidelberg

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Havemann, K., Gropp, C., Lehmann, FG., Preisser, P., von Kleist, S. (1979). Tumor-Associated Antigens in Bronchogenic Carcinoma. In: Flad, HD., Herfarth, C., Betzler, M. (eds) Immunodiagnosis and Immunotherapy of Malignant Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67166-1_8

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  • DOI: https://doi.org/10.1007/978-3-642-67166-1_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09161-5

  • Online ISBN: 978-3-642-67166-1

  • eBook Packages: Springer Book Archive

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