Abstract
Based on the investigations of Penner and Klein (9), the opinion is met often in the literature that endotoxin of gram negative bacteria acts directly on the central nervous system and thereby triggers partially or entirely the secondary symptoms of endotoxin shock (4, 5).
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Schmahl, F.W., Schlote, W., Heuser, D., Betz, E., Urbaschek, B. (1975). The Significance of Cerebral Cortical Hypoxia in Experimental Shock Induced by Endotoxin. In: Langfitt, T.W., McHenry, L.C., Reivich, M., Wollman, H. (eds) Cerebral Circulation and Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65814-3_50
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