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Synergetics of Fluid-Dynamic and Biochemical Catastrophe Reactions in Coronary Artery Thrombosis

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Unstable Angina

Abstract

The cardiovascular system is an ensemble of dynamic elements (pumps, conduits, and feedback regulators) that offers a striking example of dynamic stability, adaptability, and efficacy in complex biological systems. The fundamental regularities of such cooperative systems have become the topic of a new scientific discipline, termed synergetics [1, 2] or chaos theory [3–7], dealing with the emanation of dynamic cooperativity in physical, chemical, and biological processes. Large-scale biological order is comprehensible as the cooperativity of many subsystems, i.e., as the result of joint efforts in dynamic systems; the latter must be construed as limited compartments in which there is a continuous flow of energy and matter. Provided that in such systems a steady state far from thermodynamic equilibrium is created, coherent behavior spontaneously sets in, i.e., an a priori unexpected, highly efficient, and stable cooperativity which is governed by universal physical and thermodynamic laws. In this context it is important to realize that synergetics is concerned with processes rather than with reactions; the consideration of forces is replaced by consideration of powers (in the classical sense of thermodynamics).

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Author information

Authors and Affiliations

  1. Abteilung Physiologie, Klinikum der RWTH, Pauwelsstrasse, 5100, Aachen, West Germany

    H. Schmid-Schönbein

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  1. H. Schmid-Schönbein
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Editors and Affiliations

  1. Universitätskrankenhaus Eppendorf — Kardiologie, Martinistraße 52, 2000, Hamburg 20, Germany

    Walter Bleifeld Professor Dr.  & Christian W. Hamm Privatdozent Dr.  & 

  2. Department of Medicine, Brigham and Women’ Hospital, Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA

    Eugene Braunwald Professor Dr.

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Schmid-Schönbein, H. (1990). Synergetics of Fluid-Dynamic and Biochemical Catastrophe Reactions in Coronary Artery Thrombosis. In: Bleifeld, W., Hamm, C.W., Braunwald, E. (eds) Unstable Angina. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61288-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-61288-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64778-9

  • Online ISBN: 978-3-642-61288-6

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