Abstract
We have studied the permeation of ciclopirox through models of a fingernail, employing two new spectroscopic methods that were recently developed by our group. One is the measurement of permeation by means of infrared attenuated total reflection (IR)-ATR spectroscopy, the other is based on a specialized nuclear magnetic resonance (NMR) microscopy technique. Both methods indicate that topically applied ciclopirox solution penetrates through the fingernail and into the skin matrix.
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References
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© 1999 Springer-Verlag Berlin Heidelberg
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Bayerl, T.M. (1999). Measurement of Ciclopirox Permeation Through Fingernail Models by Novel Spectroscopic Techniques. In: Shuster, S. (eds) Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58401-5_5
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DOI: https://doi.org/10.1007/978-3-642-58401-5_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-65494-0
Online ISBN: 978-3-642-58401-5
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