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Prevention of Port-Site Recurrences: Role of Therapeutic Pneumoperitoneum

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Port-Site and Wound Recurrences in Cancer Surgery
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Abstract

The automated carbon dioxide (CO2)-pneumoperitoneum was introduced by Semm in 1980 and is now the accepted standard for exposing the abdominal cavity during laparoscopic procedures (Semm 1980). In the meantime, CO2-pneumoperitoneum has been demonstrated to have several side effects. In particular, it has recently been documented that CO2 stimulates tumor growth after laparoscopy for cancer (Jones et aI. 1995a), and that it increases bacterial translocation in peritonitis (Bloechle et al. 1998). CO2 pneumoperitoneum induces a severe acidosis at the peritoneal surface in the animal model (Shah et al., SAGES meeting 1999) and causes morphological changes in mesothelial cells (Bloechle et al. 1999).

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Ridwelski, K., Pross, M., Reymond, M.A. (2000). Prevention of Port-Site Recurrences: Role of Therapeutic Pneumoperitoneum. In: Reymond, M.A., Bonjer, H.J., Köckerling, F. (eds) Port-Site and Wound Recurrences in Cancer Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57028-5_17

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  • DOI: https://doi.org/10.1007/978-3-642-57028-5_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63117-7

  • Online ISBN: 978-3-642-57028-5

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