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Pathogenesis: Immunological Aspects of Clinical Studies

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Port-Site and Wound Recurrences in Cancer Surgery

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Abstract

The risk of port-site recurrence after laparoscopic management of digestive cancer is a serious cause of concern for digestive surgeons. Among the various factors affecting tumor port-site seeding and growth, the immune changes induced by the laparoscopic procedure may play a major role. These changes in cell-mediated immunity have mainly been investigated in experimental studies, and information on the immunological status in patients is limited, restricted to a small number of acute phase protein, cytokine and hormone serological assays in few clinical studies, sometimes linked to investigations on systemic immune status.

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Authors
  1. D. Mutter
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  2. M. Aprahamian
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Editor information

Editors and Affiliations

  1. Department of Surgery, University Hospital of Magdeburg, Leipziger Strasse 44, Magdeburg, 39120, Germany

    Marc A. Reymond M.D. (Associate Professor of Surgery) (Associate Professor of Surgery)

  2. University Hospital Rotterdam Dijkzigt Hospital, Rotterdam, 3000 CA, PO Box 2040, The Netherlands

    H. Jaap Bonjer M.D., Ph.D. (Head of Laparoscopic Surgery and Acting Head of Endocrine Surgery) (Head of Laparoscopic Surgery and Acting Head of Endocrine Surgery)

  3. Hanover Hospital, Roesebeckstrasse 15 Siloah, Hannover, 30449, Germany

    Ferdinand Köckerling M.D. (Professor of Surgery and Head Department of Surgery and Center for Minimally Invasive Surgery) (Professor of Surgery and Head Department of Surgery and Center for Minimally Invasive Surgery)

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© 2000 Springer-Verlag Berlin Heidelberg

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Mutter, D., Aprahamian, M. (2000). Pathogenesis: Immunological Aspects of Clinical Studies. In: Reymond, M.A., Bonjer, H.J., Köckerling, F. (eds) Port-Site and Wound Recurrences in Cancer Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57028-5_13

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  • DOI: https://doi.org/10.1007/978-3-642-57028-5_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63117-7

  • Online ISBN: 978-3-642-57028-5

  • eBook Packages: Springer Book Archive

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