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Multiple Sclerosis

  • Chapter
Recent Advances in Diagnostic Neuroradiology

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Multiple sclerosis (MS) is the most common neurological disease among young adults in temperate climates, with the onset usually between the ages of 20 and 40 years, affecting twice as many women as men. MS is a chronic inflammatory disease of the central nervous system (CNS), pathologically characterized by infiltration of immune cells into the CNS, localized myelin destruction, most likely due to autoimmune reactions against myelin proteins, and loss of oligodendrocytes and axons (Bruck et al. 1997; Mc Donald et al. 1992). Neurologically, MS is characterized by progressive disability of neurological functions, for example coordination, sensibility, pyramidal or urological functions. In MS, several specific patterns of the clinical disease course can be distinguished (Lublin and Reingold 1996) (Fig. 16.1).

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Authors and Affiliations

  1. Department of Radiology, MR Centre for MS Research Academic Hospital “Vrije Universiteit”, PO Box 7057, 1007-MB, Amsterdam, The Netherlands

    Elisabeth Bergers MD, PhD & Frederik Barkhof MD, PhD

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  1. Elisabeth Bergers MD, PhD
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  2. Frederik Barkhof MD, PhD
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Editors and Affiliations

  1. Department of Radiology, University Hospitals K.U.L., Herestraat 49, 3000, Leuven, Belgium

    Philippe Demaerel MD, PhD (Professor) (Professor)

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© 2001 Springer-Verlag Berlin Heidelberg

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Bergers, E., Barkhof, F. (2001). Multiple Sclerosis. In: Demaerel, P. (eds) Recent Advances in Diagnostic Neuroradiology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56662-2_16

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  • DOI: https://doi.org/10.1007/978-3-642-56662-2_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63003-3

  • Online ISBN: 978-3-642-56662-2

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