Abstract
To assess the effects of exposure to toxic stimuli, the U.S. National Toxicology Program (NTP) conducts bioassays in various organisms, each with a different biological endpoint. Mutagenic damage, as indicated by the Salmonella assay (Ames et al., 1975), is a major concern. The Salmonella assay occupies a central role in the genotoxicity testing program undertaken by the NTP. This program has involved numerous chemicals, tested under code, and under strictly controlled protocols at a number of laboratories.
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© 1991 Springer-Verlag Berlin Heidelberg
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Piegorsch, W.W., Zeiger, E. (1991). Measuring Intra-Assay Agreement for the Ames Salmonella Assay. In: Hothorn, L. (eds) Statistical Methods in Toxicology. Lecture Notes in Medical Informatics, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48736-1_5
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DOI: https://doi.org/10.1007/978-3-642-48736-1_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-53621-5
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