Abstract
The Ames or Salmonella/microsome assay (Ames et al., 1973, 1975) is the most prominent example of a short-term mutagenicity test. Originally developed and widely used for the selection of potentially mutagenic (and carcinogenic) compounds in a relatively — compared to long-term animal experiments — short period of time, it has also been used for the biological monitoring of humans exposed to environmental pollutants (Berlin et al., 1984; Margolin, 1988).
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© 1991 Springer-Verlag Berlin Heidelberg
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Schumacher, M., Schmoor, C. (1991). Statistical Analysis of the Ames Assay. In: Hothorn, L. (eds) Statistical Methods in Toxicology. Lecture Notes in Medical Informatics, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48736-1_2
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DOI: https://doi.org/10.1007/978-3-642-48736-1_2
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