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Muskulo-Skeletal Interventions

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CT- and MR-Guided Interventions in Radiology

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Abstract

Radiofrequency (RF) ablation was shown to be an effective minimal invasive tool in the treatment of both malignant and benign bone lesions (Ruiz Santiago et al. 2011; Callstrom et al. 2002). Especially in the therapy of osteoid osteoma, image-guided RF ablation has emerged to be the gold standard. Osteoid osteoma is benign bone tumor which was first described by Jaffe in 1935 (Jaffe 1935). Histologically, it consists of a centrally located nidus composed of osteoblasts and osteoid which is surrounded by an area of reactive sclerosis and/or periosteal new bone formation. Prostaglandins which are produced by the tumor induce a chronic inflammatory reaction and vasodilatation which results in stimulation of unmyelinated nerve endings in the nidus causing pain. This leads to the clinical symptoms of this lesion with local pain often worsened during the night, which is typically relieved by aspirin or other related nonsteroidal anti-inflammatory drugs. Osteoid osteomas occur more frequently in men than in women (2:1), and most patients, approximately 75 %, suffering from osteoid osteomas are between 5 and 25 years old. Most commonly, osteoid osteomas are found in the diaphysis of femur and tibia followed by humerus, radius, ulna, hand, and the vertebral spine. A malignant transformation of osteoid osteoma is not known.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, D-52074, Aachen, Germany

    Philipp Bruners

  2. Department of Diagnostic and Interventional Radiology, University Hospital, Marburg, Germany

    Andreas H. Mahnken

  3. Philipps University of Marburg, Marburg, Germany

    Andreas H. Mahnken

  4. Department of Radiology, University Hospital Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany

    Kai E. Wilhelm

  5. Department of Interventional Radiology, University of Basel, Petersgraben 4, CH-4031, Basel, Switzerland

    Sebastian Kos, Peter Messmer, Deniz Bilecen & Augustinus L. Jacob

  6. Department of Radiology, University Hospital Gießen, Klinikstraße 33, D-35392, Gießen, Germany

    Gabriele A. Krombach

  7. Radiologie im Liebig-Center, Bahnhofstraße 64, 35390, Gießen, Germany

    Oliver Wüsten

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  1. Philipp Bruners
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  3. Kai E. Wilhelm
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  4. Sebastian Kos
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  6. Deniz Bilecen
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  7. Augustinus L. Jacob
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  8. Gabriele A. Krombach
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  9. Oliver Wüsten
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Correspondence to Philipp Bruners .

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Editors and Affiliations

  1. Philipps University Marburg, Department of Radiology, University Hospital Giessen and Marburg, Baldingerstr., Marburg, 35033, Germany

    Andreas H. Mahnken

  2. , Department of Radiology, University of Bonn, Sigmund-Freund-Strasse 25, Bonn, 53127, Germany

    Kai E. Wilhelm

  3. Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany

    Jens Ricke

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Bruners, P. et al. (2013). Muskulo-Skeletal Interventions. In: Mahnken, A., Wilhelm, K., Ricke, J. (eds) CT- and MR-Guided Interventions in Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-33581-5_15

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