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Contributions to Medical and Scientific Literature

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FESTSCHRIFT The Institute of Nuclear Medicine 50 Years

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Abstract

Inevitably there are omissions from the list, especially of papers published in the earlier years.

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Reference

Books and Monographs

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  2. Britton, K.E. and Brown, N.J.G. Clinical Renography, pp298 (Lloyd Luke), 1971 3. Ell, P.J., Jarritt, P.H. and Deacon, M.J. Atlas of Computerized Emission Tomography, pp225 (Churchill Livingstone), 1980.

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  5. Ell, P.J., Walton S. and Jarritt, P.H. Radionuclide Ventricular Function Studies, pp171 (Martinus Nijhoff), 1982.

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  7. Jarritt, P.H and Ell, P.J. Gamma Camera Emission Tomography Quality Control and Clinical Applications. pp190, (Current Medial Literature), 1984.

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Cardiology

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  2. Ell P.J. “Scan analysis in Myocardial Infarction” Nuklearmedizin, XV, 157–159, 1976.

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  3. Ell P.J., Elliott, A.T., and Marcomichaelaidis I. “Myocardial Perfusion Imaging”. The Lancet, I, 304, 1977.

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  4. Ell P.J. “A Cintigrafia do miocardio”. Revista de Terapeutica e Clinica Medica, 3, 127–134, 1977.

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  5. Joseph S., Ell P.J., Langford, R.M., Pearce, P.C., and Woolf N. Tc99m Imidodiphosphonate: a new radiopharmaceutical for positive myocardial infarction imaging. British Heart Journal, 39, 924, 1977.

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  8. Ell P.J. and Donaldson R.M. “Cardiovascular Nuclear Medicine and Intensive Care Medicine” Intensive Care Medicine, 4, 119–122, 1978.

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  10. Joseph S.P., Pereira-Prestes A.V., Ell P.J., Donaldson R.M., Somerville W and Emanuel R.W. The value of positive myocardial infarction imaging in the coronary care unit. British Medical Journal, 1, 361–432, 1979.

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  11. Donaldson R.M., Jarritt, P.H, Liversedge S. and Ell P.J. Ventricular Pseudo-Aneurysm Demonstrated by Multiple Gated Cardiac Imaging. Nuklearmedizin, 18, 283–285, 1979.

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  12. Ell P.J. The role of 99mTechnetium labelled phosphate in the diagnosis of acute myocardial infarction. British Journal of Radiology, 53, 178, 1980.

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  14. Ell P.J. 201Thallium – clinical applications. Revista Latina de Cardiologia, 1, 123–126, 1980.

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  16. Ell P.J. and Khan O. Emission Computerized Tomography, Clinical Application. Seminars in Nuclear Medicine, Vol II, 50–60, 1981.

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  18. Walton S., Brown, N.J.G., Ell P.J., Jarritt, P.H and Swanton. Phase analysis of the first pass radionuclide angiocardiogram. Nuclear Medicine Communications, 2, 93, 1981.

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  20. Khan O., Ell P.J., Cullum I.D., Jarritt, P.H, Williams E.S. Clinical and pharmacological studies with 99mTc-plasmin. Progress in Radiopharmacology,Vol. 2, ed. Ed. P.H. Cox, Elsevier, North Holland Biomedical Press. 1981.

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  21. Walton S., Ell P.J., Jarritt, P.H, and Swanton, R.H. Phase analysis of the first pass radionuclide angiocardiogram. British Heart Journal, 48, 441–448, 1982.

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  22. Walton S., Brown, N.J.G., Jarritt, P.H, Ell P.J. and Emanuel R.W. Regional variation of left ventricular transit time in normal ventricles and those with abnormalities of contraction. British Heart Journal, 49, 388–392, 1983.

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  23. Underwood, S.R., Ell P.J., Jarritt, P.H., Emanuel R.W. and Swanton, R.H. ECG gated blood pool tomography in the determination of left ventricular volume, ejection fraction and wall motion. Nuclear Medicine Communications, 5, 258, 1984.

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  24. Underwood, S.R. and Ell P.J. La imagen de fase en la ventriculografia isotopica. Revista Latina de Cardiologia, 5, 139–146, 1984.

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  26. Underwood, S.R., Walton S., Laming P.J., Jarritt, P.H, Ell P.J., Emanuel R.W, and Swanton, R.H. Three dimensional quantification of left ventricular wall motion by ECG gated blood pool emission tomography. British Heart Journal, 91, 1984.

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  28. Walton S., Costa D.C., Ell P.J., Emanuel R.W. Myocardial Imaging with Iodine 123 Metaiodobenzylguanidine. British Heart Journal, 56, 617, 1985,

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  30. Underwood, S.R., Walton S., and Ell P.J. Paradoxical phase changes induced by myocardial ischaemia. Nuclear Medicine Communications, 6, 225–228, 1985.

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  33. Mosley, J.G., Clark J.M.F, Ell P.J. and Marston A. Assessment of myocardial function before aortic surgery by radionuclide angiocardiography. British Journal of Surgery, 72, 886–887, 1985.

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  34. Smith, P.L.C., Joseph P.L.A., Newman, S.P., Ell P.J., Harrison, M.J.F. and Treasure T. Cerebral consequences of coronary artery surgery. British Heart Journal, 54, 639, 1985.

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  35. Smith, P.L.C., Newman, S.P., Ell P.J., Treasure T., Joseph S.P., Schneidan A., and Harrison M.J.G. Cerebral consequences of cardiopulmonary bypass. The Lancet, I, 823–825, 1986.

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  36. Ell P.J. and Underwood, S.R. Does it help to know the left ventricular ejection fraction. The Lancet I, 909, 1986.

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Central Nervous System

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  3. Vaughan-Hudson G. Carotid flow disorders in patients with cerebrovascular disease: Their atraumatic assessment by carotigraphy. British Journal of Surgery, 61, 873–877, 1974.

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  4. Ell P.J. and Meixner M. Non-invasive investigation of the brain. British Medical Journal, 40, 3, 1975.

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  5. Ell P.J., Lotritsch K.H., Hillbrand E., Meixner M., Barolin G. and Scholz H. Specific diagnosis of brain disease with double isotope brain scanning. Nuklearmedizin, XV, 1, 32–35, 1976.

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  6. Ell P.J., Lotritsch K.H. and Meixner M. Differential diagnosis of brain lesions with Tc-99m labelled pharmaceuticals. Nuclear Medicine, 17, 224, 976.

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  7. Meixner M. and Ell P.J. Brain Scanning: A step towards histological diagnosis with Tc-99m-labelled radiopharmaceuticals. European Journal of Nuclear Medicine, 1, 95, 1976.

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  8. Britton, K.E. and Williams E.S. E.M.I. and radioisotope brain imaging. The Lancet, I, 477–478, 1976.

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  9. Ell P.J. Isotope scans in chronic subdural haematoma. The Lancet, II, 592, 1979.

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  10. Harrison M.G.J. and Ell P.J. Ischaemic oedema in stroke. Stroke, 12, 888, 1981.

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  11. Ell P.J., Harrison M.G.J., Lui D. Cerebral blood flow with Iodine-123 labelled amines. The Lancet, I, 1348–1352, 1983.

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  12. Ell P.J., Williams E.S. and Deacon, M.J. Clinical efficacy study of ECAT and TCAT brain scans in 118 patients. Radioaktive Isotope in Klinik und Forschung, 1980, 14, 245–249.

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  13. Ell P.J., Deacon, M.J., Ducassou D. and Brendel A. Emission and transmission brain tomography. British Medical Journal, 3, 438–440, 1980.

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  14. Steiner, T.J., Ell P.J., Jewkes R and Clifford-Rose F. Cleon-710 cerebral blood flow tomography after acute cerebral infarction. Nuclear Medicine Communications, 5, 232m 1984.

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  16. Ell, P.J., Hocknell, J.M.L., Jarritt, P.H, Cullum I.D., Lui D., Campos-Costa D., Nowotnik, D.P., Pickett R.D., Canning L.R., and Neirinckx, R.D. A Tc-9m-labelled radiotracer for the investigation of cerebral vascular disease. Nuclear Medicine Communications 6, 437–441, 1985.

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  17. Ell P.J. Regional cerebral blood flow and Tc-99m. Editorial. Nuclear Medicine Communications 6, 435–436, 1985.

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  18. Ell P.J., Cullum I.D., Costa D.C. et al. Regional cerebral blood flow mapping with a new Tc-99m-labelled compound. The Lancet, II, 50–51, 1985.

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  20. Nowotnik, D.P., Canning L.R., Cumming S.A., Nechvatal G., Piper I.M., Pickett R.D., Neirinckx R.D., Ell P.J., Volkert W.A. and Holmes R.S. Tc-99m-HM-PAO: A new radiopharmaceutical for imaging regional cerebral blood flow. J. Nucl. Med. All, Sco., 29, 3, 209, 1985.

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  22. Ell P.J. and Costa D.C. Regional cerebral blood flow and Tc-99m: towards a routine SPET test, Diagnostic Imaging, 8, 112–117, 1986.

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  23. Hocknell, J.M.L., Cullum I.D., Smith, P.L.C., Costa D.C. and Ell P.J. Clinical studies using a new regional cerebral blood flow agent 99m-Tc-hexamethyl-propyleneamine oxime (HM-PAO). Nuclear Medicine Communications, 7, 295, 1986.

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  24. Costa D.C., Jones B.E., Steiner T.J., Aspey B.S., Ell P.J., Cullum I.D., Jeweks R.F. Experimental studies of Tc-99m HM-PAO with an rCBF model. Nuclear Medicine Communications, 7, 282, 1986.

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Computer Applications

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  2. Todd-Pokropek A.E. Methods of extracting digital data in radioisotope scanning. British Journal of Radiology, 40, 158, 1967.

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  4. Todd-Pokropek A.E. Methods of developing a system of data analysis of the radioisotope. Proc. Symp. ‘Radioactive isotopes in the localisation of tumours’ (Heinmann, London), 50, 1969.

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  5. Todd-Pokropek A.E. and Newman G.B. The choice of a computer for on-line processing of radioisotope scans, British Journal of Radiology, 44, 76, 1971.

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  6. Todd-Pokropek A.E. Theoretical considerations when using various computer enhancing methods for the radioisotope scan, L’utilisation des ordinateurs en radiologie,(Karger, Basle), 291–296, 1971.

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  9. Brown, N.J.G., Budd T., Britton, K.E. On the transmission of quantitative difference information via an interactive computer system to the clinical interpreter. Proc. IVth Int. Conf. on Information Processing in Scintigraphy. Ed. Raynaud E.C., Todd-Pokropek A.E. French Atomic Energy Commission, Orsay, Paris 1976.

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  10. Brown, N.J.G., Elliott A.T., Burns D., Ell P.J. Operating a Nuclear Medicine computer system with a remote mobile gamma camera. Physics in Medicine and Biology, 23, 981–985, 1978.

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  11. Ekins R.P., Malan P.G. Computerization in RIA and quality control. Proceedings of conference Computers in the Clinical Laboratory Dusseldorf, 19–20 November, 1979.

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  12. Edwards P.R. and Ekins R.P. Development of a microcomputer immunoassay RIA data processing programme for WHO laboratories. In Radioimmunoassay and Related Procedures in Medicine, 1982, IAEA, Vienna, 1982.

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Endocrinology

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  2. Sonksen R.P., Ekins R.P., Stevens H.G., Williams E.S. and Nabarro J.D.N. Serum levels of protein bound iodine and thyroxine after a course of clioquinol. The Lancet, II, 425, 1968.

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  4. Williams E.S., Ekins R.P., Ellis S.M. Thyroid suppression test with serum thyroxine concentration as index of suppression. British Medical Journal 4, 338–340, 1969.

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  5. Harvey R.F., Williams E.S., Ellis S.M. and Ekins R.P. Changes in thyroxine-binding globulin levels in thyrotoxicosis and in healthy subjects after triiodothyronine administration. Acta Endocrinologica, 63, 527–532, 1970.

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  6. Jacobs H.S. and Williams E.S. Effect of propranolol on serum thyroxine. The Lancet, II, 829, 1970.

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  7. Lawton N.F., Ekins R.P. and Nabarro J.D.N. Failure of pituitary response to thyrotrophin-releasing hormone in euthyroid Graves’disease. The Lancet, II, 14, 1971.

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  8. Williams E.S., Ekins R.P. and Ellis S.M. Thyroid hormone concentration in serum after thyroid stimulation. J. Endocrin. XI, 49, 1971.

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  9. Williams E.S. and Keeling D.H. Changes in the normal range of thyroidal radioiodine uptake. Journal of Clinical Pathology, 25, 863–866, 1972.

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  15. Britton, K.E. and Ell P.J. Thyroid scanning. British Medical Journal, 2, 728, 1973.

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  19. Britton, K.E., Quinn V., Ellis S.M., Cayley A.C.D., Miralles J.M., Brown B.L., and Ekins R.P. Is T-4 toxicosis a normal biochemical finding in elderly women? The Lancet, I, 141, 1975.

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  20. Eastman C.J., Corcoran J.M., Ekins R.P., Williams E.S. and Nabarro J.D.N. The radioimmunoassay of Triiodothyronine and its clinical application. Journal of Clinical Pathology, 28, 225–230, 1975.

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  21. Ell P.J. and Lotritsch K.H. Importancia do Tc-99m em medicina. II. O Tc-99m-pertecnetato nas provas de funcao tiroideia. Medicina Universal, 18, 5–6, 1975.

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  22. Ell P.J., Todd-Pokropek, A.E. and Britton, K.E. Localization of parathyroid adenomas by computer assisted parathyroid scanning. British Journal of Surgery, 62, 553–555, 1975.

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  23. Britton, K.E., Quinn V., Brown, B.L. and Ekins R.P. A strategy for thyroid function tests. British Medical Journal, 3, 350, 1975.

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  25. Pharoah P.O.D., Ellis S.M., Ekins R.P. and Williams E.S. Maternal thyroid function, iodine deficiency and fetal development. Clinical Endocrinology, 5, 159–166, 1976.

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  26. Marshall N.J., von Borcke S. and Ekins R.P. Independence of β-adrenergic and TSH receptors linked to adenylate cycles in the thyroid. Nature, 261, 603, 1976.

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General Topics

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  42. Williams E.S. Radioactive isotopes and their use as diagnostic agents. In Scientific Foundations of Obstetrics and Gynaecology, Heinemann, 1977.

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  45. Cotton P.B., Britton, K.E., Hazra D.K., Stern R.B., Ponder B.A.J., Croft D.N. Is pancreatic isotope scanning worthwhile? British Medical Journal, 1, 282–283, 1978.

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  48. Ell P.J., Todd-Pokropek A.E. and Williams E.S. The future of Nuclear Medicine imaging. Fortschritte auf dem Gebriet der Rontgenstrahlen und der Nuklearmedizin, 128, 486–490, 1978.

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  50. Ell P.J., Deacon J.M., Jarritt, P.H. and Williams E.S. Emission computerized tomography. Clinical Science, 56, 24, 1979.

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  51. Deckart H., Ell P.J., Pfitzmann A., Blottner A., Brunhober J.R., Janiszewski R. and Weiland,J. Experimentelle und Klinische Ergebnisse der Gallenwegsszintigraphie mit 99m-Tc-Diaethyl-IDA. Radiologie und Radiotherapie,122–123, 1979.

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  53. Dunn E.C, Ebringer R.W. and Ell P.J. Quantitative scintigraphy in the early diagnosis of sacroilitis. Rheumatology and Rehabilitation, 19, 69–75, 1980.

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  55. Deacon J.M., Ell P.J., Anderson A. and Khan O. 99m-Tc-Plasmin: a new test for the detection of deep vein thrombosis. British Journal of Radiology, 53, 673–677, 1980.

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  61. Williams E.S. Medical training in Nuclear Medicine. Nuclear Medicine Communications, 1, 107–109, 1980.

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  69. Ell P.J. Single photon emission tomography. Editorial, The Lancet, II, 138, 1982.

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  76. Ell P.J. Imaging with lipophy lic tracers: clinical implications. Physics in Medicine and Biology, 30, 605, 1985.

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  77. Ell P.J. Non-invasive assessment of oesophageal transit. Invited Editorial. Acta Medica Portuguesae, 6, 67–69, 1985.

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  78. Ell P.J. Comparison of intravenous digital subtraction angiography with radionuclide V/Q lung scanning in patients with suspected pulmonary embolism. Thorax, 40, 576–580, 1985.

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Nephrology

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  19. Britton, K.E., Cage P.E. and Carson E.R. A ‘Bootstrap’ model of the renal medulla. Postgraduate Medical Journal, 52, 279, 1976.

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Oncology

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  4. Britton, K.E., Brown, N.J.G., Smith L.A., Glover G., Myers M.J., Goodwin T.J. and Bluhm M.M. Early adrenal tumour localisation. In Quality Factors in Nuclear Medicine, 1, p29. Ed. Munkner T. Fadl.s.Forlag, Copenhagen 1975.

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  6. Ell P.J. and Lotritsch K.H. O despiste precoce de metastase osseas e a cintigrafia do esqueleto pelos fosfatos marcados com on Tc-99m. Revista Portuguesa de Clinica e Terapeutica, 2, 83–90, 1976.

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  10. Ell P.J. Early diagnosis and space occupying disease; an ever increasing complex problem. Acta Medica Portuguesa, 1, 109–116, 1979.

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  13. Khan O., Ell P.J., MacLennann K.A., Kurtz A.B. and Williams E.S. Thyroid carcinoma in an autonomously hyperfunctioning thyroid nodule. Postgraduate Medical Journal, 57, 39–42, 1981.

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Physiology

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  5. Britton, K.E. Renin and renal autoregulation. The Lancet, II, 329–33, 1968.

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  6. Slater D.J.H., Williams E.S., Edwards R.H.T., Ekins R.P., Sonksen P.H., Beresford C.H. and McLaughlin M. Potassium retention during the respiratory alkalosis of mild hypoxia in man: its relationship to aldosterone secretion and other metabolic changes. Clinical Science, 37, 311–326, 1969.

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  8. Tuffley R.W., Rubenstein D., Slater D.J.H. and Williams E.S. Serum renin activity during exposure to hypoxia. Journal of Endocrinology, 49, 497–510, 1970.

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  14. Williams E.S. Mountaineering and the endocrine system. In Mountain Medicine and Physiology, Alpine Club, 1975.

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  34. Bidey S.P., Marshall N.J. and Ekins R.P. Inhibition by normal immunoglobulins of thyrotrophin- stimulated production of cyclic AMP in slices of normal human thyroid.

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  39. Ekins R.P. The biological significance and measurement of “free” hormones in blood. In: Recent Advances in Endocrinology and Metabolism, 2. ed. J.H.L. O’Riordan, Churchill Livingstone, Edinburgh, 287, 1981.

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  42. Bidey S.P., Marshall N.J. and Ekins R.P. Adenylate cyclase activity and the accumulation and release of adenosine d’5’-monophosphate in normal human thyroid tissue slice preparations: responses to thyrotrophin and thyroid stimulating antibodies. Journal of Clinical Endocrinology & Metabology, 53, 264–253, 1981.

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  45. Ekins R.P., Edwards P.R., and Newman B. The role of binding proteins in hormone delivery. In: A. Albertini and R.P. Ekins (Eds) Free Hormones in Blood. Elsevier Biomedical Press, Amsterdam, 1982.

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Radiation Protection

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Radioimmunoassay and Related Topics

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  3. Ekins R.P. and Samols E. Immunoassay of insulin with insulin antibody precipitate. The Lancet 2, 202, 1963.

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  5. Ekins R.P. and Sgherzi A.M. The microassay of vitamin B-12 in human plasma by the saturation assay technique. In: Radioaktive Isotope in Klinik und Forschung, VI, 446–473, Urban und Schwarzenberg, 1965.

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  7. Ekins R.P. Microanalysis of some vitamins and hormones in blood. Brit. J. Radiol. 37, 723, 1964.

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  8. Ekins R.P. and Sgherzi A.M. Intrinsic factor assay. The Lancet 2, 1242–1243, 1964.

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  9. Ekins R.P., Newman G.B. and O’Riordan J.L.H. Theoretical aspects of ‘Saturation’ and radioimmunoassay. In Radioisotopes in Medicine: In Vitro Studies, R.L. Hayes, F.A. Goswitz, B.E.P. Murphy, eds, U.S.A.E.C., Oak Ridge, Tenn, 59–100, 1968.

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  10. Ekins R.P., Newman G.B. and O’Riordan J.L.H. Saturation Assays. Statistics in Endocrinology, 345–378, 1968.

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  11. Ekins R.P. and Newman G.B. The optimisation of precision and sensitivity in the radioimmunoassay method. In: Protein and polypeptide hormones, 2, M. Margoulies, Ed., Exceprta Medica Foundation, Amsterdam, 329, 1968.

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  13. Ekins R.P. Problems of sensitivity with special reference to optimal conditions. In: Protein and polypeptide hormones, 3, M. Margoulies, Ed., Excerpta Medica Foundation, Amsterdam, 672, 1968.

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  14. Albano J.D.M. and Ekins R.P. The fundamental principles governing the attainment of high sensitivity and precision in radioimmunoassay techniques and their exemplification in a method for the assay of serum insulin. Acta Endocrinologia Supply 138, 61, 2, 1969.

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  16. Ekins R.P. Theoretical aspects of saturation analysis. Proc. Int. Symp. on In vitro procedures with radioisotopes in Medicine, IAEA, Vienna, 1969, Printed in Vienna, 1970.

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  17. Albano J., and Ekins R.P. Attainment of high sensitivity and precision in radioimmunoassay techniques in a simple assay of serum insulin. Proc. Int. Symp. on In vitro procedures with radioisotopes in Medicine, IAEA, Vienna, 1969, Printed in Vienna, 1970.

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  18. Brown B.L., Ekins R.P., Ellis S.M. and Reith W.S. A specific saturation assay technique for serum Triiodothyronine. Proc. Int. Symp. on In vitro procedures with radioisotopes in Medicine, IAEA, Vienna, 1969, Printed in Vienna, 1970.

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  19. Vyzantiades A., Ekins R.P. and Slater D.J.H. The characterisation and localisation of high-energy-binding sites in mammalian and amphibian kidney and amphibian bladder; preliminary studies for the assay of aldosterone by saturation analysis. Proc. Int. Symp. on In vitro procedures with radioisotopes in Medicine, IAEA, Vienna, 1969, Printed in Vienna, 1970.

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  20. Ekins R.P. Immunoassay. British Journal of Hospital Medicine, 930, 1969.

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  21. Ekins R.P., Williams E.S. and Ellis S.M. The sensitive and precise measurement of serum thyroxine by saturation analysis (competitive protein binding assay). Clin. Biochem., 2, 253–288, 1969.

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  22. Cotes, P.M., Mussett M.V., Berryman I., Ekins R.P., Glover S., Hales N., Hunter W.M., Lowy C.N.R.W.J., Samols E. and Woodward P.M. Collaborative study of estimates by radioimmunoassay of insulin concentrations in plasma samples examined in groups of 5 or 6 laboratories. Journal of Endocrinology, 45, 557–569, 1969.

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  23. Ekins R.P. Saturation analysis. Clinical Science, 570, 1969.

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  24. Brown B.L., Ekins R.P., Ellis S.M. and Reith W.S. Specific antibodies to Triiodothyronine hormone. Nature, 226, 359, 1970.

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  25. Ekins R.P. and Newman G.B. Theoretical aspects of saturation analysis. Acta Endocrinologica, 64, Suppl. 147, 11–30, 1970.

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  26. Ekins R.P. Radioimmunoassay of thyroid and steroid hormones. British Journal of Radiology, 43, 828, 1970.

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  27. Brown B.L., Ekins R.P. and Tampion W. The assay of adenosine3’5’-cyclic monophosphate by saturation analysis. Biochemical Journal, 120, 8, 1970.

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  28. Brown B.L., Albano J.D.M., Ekins R.P. and Sgherzi A.M. A simple and sensitive saturation assay method for the measurement of adenosine 3’5’-cyclic monophosphate. Biochemical Journal, 121, 561, 1971.

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  29. Ekins R.P. Radioimmunoassay protein-binding assay and other saturation assay techniques. The Prationer, 207, 312–321, 1971.

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  30. Piyasena R.D.M., Ekins R.P. and Slater D.J.H. The determination of corticosterone levels in human plasma by saturation analysis.

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  31. Brown B.L., Ekins R.P., Sgherzi A.M. and Tampion W. Saturation analysis of cyclic AMP. Journal of Endocrinology, 49, xvii, 1971.

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  32. Banks P., Ekins R.P. and Slater D.J.H. Development of a rapid, sensitive and specific method for the measurement of aldosterone by radioimmunoassay. Acta Endocrinologica, (Kbh) Suppl. 155, 94, 1971.

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  33. Ekins R.P. and Brown B.L. Cyclic nucleotides and thyroid hormones: radioimmunoassay or protein-binding assay? Biochemical Journal, 126, No. 3, 1, 1971.

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  34. Brown B.L., Ekins R.P., Ellis S.M. and Williams E.S. The radioimmunoassay of Triiodothyronine. In: Further advance in thyroid research, 1107–1120, 1971. K. Fellinger and R. Hofer, eds.

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  35. Albano J.D.M., Ekins R.P., Martiz G. and Turner R.C. A sensitive precise radioimmunoassay of serum insulin relying on charcoal separation of bound and free hormone moieties. Acta Endocrinologica, 70, 487–509, 1972.

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  36. Ekins R.P., Newman G.B., Piyasena R., Banks P. and Slater D.J.H. The radioimmunoassay of aldosterone in serum and urine: theoretical and practical aspects. Journal of Steroid Biochemistry, 3, 289–304, 1972.

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  37. SufiS.B., Toccafondi R.S., Malan P.G. and Ekins R.P. Binding of thyroid hormones to a soluble fraction from porcine anterior pituitary. Journal of Endocrinology, 58, 41–52, 1973.

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  38. Ekins R.P. and Newman G.P. Optimisation of radioimmunoassay, proteinbinding and other saturation assay techniques. Journal of Endocrinology, 58, xxi, 1973.

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  39. Corcoran J.M., Eastman C.J., Ekins R.P. and Paul W. The production of antisera for the radioimmunoassay of thyroxine. Journal of Endocrinology, 58, xxii, 1973.

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  40. Eastman C.J., Corcoran J.M., Millar J.G.B., Weschler N., Lawton N.F., Ekins R.P. and Nabarro J.D.N. Radioimmunoassay of serum triiodothyronine in patients with thyroid disease. Journal of Endocrinology, 58, xxii, 1973.

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  41. Malan P.G., Newman G.B. and Ekins R.P. Non-linear curve fitting to radioimmunoassay standard curves. Acta Endocrinologica, (Kbh), Suppl. 177, 99, 1973.

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  42. Ellis S.M. and Ekins R.P. The direct measurement by radioimmunoassay of the free thyroid hormone concentrations in serum. Acta Endocrinologica (Kbh), Suppl. 177, 106, 1973.

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  43. Ekins R.P. Automation in radioimmunoassay. Acta Endocrinologica, (Kbh), Suppl. 177, 383, 1973.

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  44. Jowett T.P., Slater D.J.H., Piyasena R.P. and Ekins R.P. Radioimmunoassay of aldosterone in plasma and urine: validation of a novel separation techniqe and a rapid urine assay. Clin. Sci. and Mol. Med., 45, 607, 1973.

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  45. Ellis S.M. and Ekins R.P. The radioimmunoassay of free (diffusible) T3 and T4 concentrations in serum. Journal of Endocrinology, 59, xiii, 1973.

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  46. Ekins R.P. Saturation analysis of vitamin B12 and data processing associated with this and similar assays. British Journal of Haematology, 25, 541, 1973.

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  47. Brown B.L., Albano J.D.M., Barnes G.D. and Ekins R.P. The saturation assay of adenosine 3’:5’-cyclic monophosphate in tissues and body fluids. Biochemical Society Transaction, 338, 1974.

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  48. Ekins R.P. Automation of radioimmunoassay and other saturation assay procedures. In: radioimmunoassay and related procedures in medicine. Vol. 1, 91–109, IAEA, Vienna.

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  49. Albano J.D.M., Barnes G.D, Maudsley D.V., Brown B.L. and Ekins R.P. Factors affecting the saturation assay of cyclic AMP in biological systems. Analytical Biochemistry, 60, 130–141, 1974.

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  50. Ekins R.P. Basic principle and theory. British Medical Bulletin (Radioimmunoassay and Saturation Analysis), 30, 3, 1974.

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  51. Eastman C.J., Corcoran J.M., Ekins R.P., Williams E.S. and Nabarro J.D.N. The radioimmunoassay of triiodothyronine and its clinical radioimmunoassay sample counting employing a microprocessor application. Journal of Clinical Pathology, 28, 225, 1975.

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  52. Ekins R.P. Automation and standardisation of radioimmunoassay. In: Proceedings of the 12th International Society of Nuclear Medicine, 636, Munich, 1974, F.K. Schattauer Verlag, Stuttgart, New York, 1975.

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  53. Ekins R.P. Radioimmunoassay Design. In: Radioimmunoassay in Clinical Biochemistry, 3–13, C.A. Pasternak, ed. 1975.

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  54. Ellis S.M. and Ekins R.P. The radioimmunoassay of serum free Triiodothyronine and thyroxine. In: Radioimmunoassay in Clinical Biochemistry 187–194, C.A. Pasternak, ed. 1975.

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  55. Sufi S.B., Malan P.G. and Ekins R.P. Interactions of thyroxine with a pituitary cytosol fraction. In: Thyroid Hormone Metabolism, 105–123. W.A. Harland and J.S. Orr, Eds. Academic Press, 1975.

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  56. Ekins R.P. and Ellis S.M. The radioimmunoassay of free thyroid hormones in serum. In: Thyroid Research, 597–600. Jacob Robbins and Lewis E. Braverman, eds, Excerpta Medica, Amsterdam, 1976.

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  57. Ekins R.P. ELISA: A replacement for radioimmunoassay? The Lancet, II, 569, 1976.

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  58. Brown B.L., Albano J.D.M., Barnes G.D., Maudsley D.V. and Ekins R.P. The assay of cyclic AMP in biological material. In Eukaryotic cell function and growth: Regulation by intracellular cyclic nucleotides, 285–25. Eds. Jacques E. Domont, Barry L. Brown and Nicholas J. Marshall. Plenum Press, New York and London 1976.

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  59. Milutinovic P., von Borcke S., Chapman R.S., Marshall N.J., Malan P.G. and Ekins R.P. Comparison of two methods for free thyroxine determination: equilibrium dialysis and immobilised antibody phase assays. Radiol. Jugosl. 12, 429–433, 1978.

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  60. Ekins R.P. and Marshall N.J. Radioassays – Developments and Trends. Proceedings of the 15th Annual Meeting of Society of Nuclear Medicine, Groningen, The Netherlands. 1977.

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  61. Ekins R.P. The future development of immunoassay. In: Radioimmunoassay and related procedures in medicine 1977. Procedings of a Symposium in Berlin, 1977, IAEA, Vienna. 1, 241–275, 1978.

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  62. Hazra D.K., Ekins R.P., Edwards P.R. and Williams E.S. Labelled antibody techniques in glycoprotein estimation. In: Radioimmunoassay and related procedures in medicine 1977. IAEA, Vienna, 1, 329–346.

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  63. Malan P.G., Cox M.G., Long E. and Ekins R.P. A multi-binding site model-based curvefitting program for the combination of RIA data. In: radioimmunoassay and related procedures in medicine. IAEA, Vienna, 1, 425–436, 1977.

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  64. Ekins R.P., Sufi S. and Malan P.G. An ‘intelligent’ approach to controlled sample counter. In: Radioimmunoassay and related procedures in medicine 1977. IAEA, Vienna, 1, 437–455, 1978.

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  65. Ekins R.P. Basic concepts in quality control. In: Radioimmunoassay and related procedures in medicine 1977. IAEA, Vienna Vol II, 6–20, 1978.

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  66. Ekins R.P. Quality control and assay design. In: Radioimmunoassay and related procedures in medicine 1977. IAEA, Vienna Vol II, 39–56, 1978.

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  67. Bidey S., Gill D., Ackroyd B., Malan P., Marshall N.J. and Ekins R.P. Optimisation of TSH radioligand receptor assays. Annales d’endocrinologie: 9th Annual Meeting of the European Thyroid Association, Berlin p. 4A, 1978.

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  68. Hazra D.K., Jain R.K., Bharti A., Ekins R.P. and Williams E.S. Labelled antibody techniques in communicable diseases. Proceedings of II International Congress of the World Federation of Nuclear Medicine and Biology, Washington, U.S.A., 17–21 September, 1978.

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  69. Ekins R.P., Malan P.G. Identification of outliners. Annals of Clin. Biochem. 15, 125–126, 1978.

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  70. Malan P.G., Cox M.G., Long E.M.R. and Ekins R.P. Curve-fitting to radioimmunoassay standard curves: spline and multiple binding – site models. Annals of Clin. Biochem. 15, 132–135, 1978.

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  71. Ekins R.P. Methods for the measurement of free thyroid hormones. In: Free Thyroid Hormones. Ed. R. Ekins, G. Faglia, F. Penisi and A. Pinchera. Excerpta Medica Amsterdam, 72–92, 1979.

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  73. Malan P.G., Chapman R.S., Redford C.R. and Ekins R.P. Results from the UK National Quality Control Schemes for T3 and T4. Annales d’Endocrinologie, 9A,1979.

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  74. Mathur H., Ekins R.P., Brown B.L., Malan P.G. and Kurtz A.B. Correction for the presence of cross-reactants in saturation assays: application to thyroxine cross-reactivity in 3,3;,5’-(reverse)- Triiodothyronine radioimmunoassay. Clinica Chimica Acta, 19, 317–327, 1979.

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  75. Ekins R.P. Commercial radioimmunoassay for free thyroxine. The Lancet, I, 1190, 1979.

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  76. Ekins R.P. The Corning Immophase Free T4 Kit. Ligand review, 1,7–9, 1979.

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  77. Ekins R.P. Radioassay methods. In: Radiopharmaceuticals II: Proceedings 2nd International Symposium on Radiopharmaceuticals, March 19–22, 1979, Seattle, Washington, 219–240, 1979.

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  78. Ekins R.P. Assay design and quality control. In: Radioimmunology 1979: Proceedings of the IVth International Sympoisum on Radioimmunology, Lyon, France, April 1979. Ed. Ch. A. Bizollon., 239–255, 1979.

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  79. Ekins R.P. and Kurtz A.B. Measurement of free ligands. UK Patent Application 7906526, 1979.

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  80. Ekins R.P., Filetti S., Kurtz A.B. and Dwyer K. A simple general method for the assay of free hormones (and drugs): its application to the measurement of serum free thyroxine levels and the bearing of assay resultson the “free thyroxine” concept. Journal of Endocrinology, 85, 29–30, 1980.

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  81. Ekins R.P. More sensitive immunoassays. Nature, 284, 14, 1980.

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  82. Ekins R.P. Merits and disadvantages of different labels and methods of immunoassay. In: Immunoassays for the 90s. Ed. A. Voller A. Bartlett and D. Bidwell. 5–16, 1980. MTP Press.

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  83. Bidey S.P., Marshall N.J. and Ekins R.P. The stimulation of cAMP accumulation in human thyroid slices: a study of its use as an assay for thyroid stimulating antibodies. Journal of Endocrinology, 87, 36, 1980.

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  84. Ealey P.A., Bidey S.P., Marshall N.J. and Ekins R.P. Use of the section cytochemical bioassay for the measurement of thyroid stimulators. Journal of Endocrinology, 87, 35, 1980.

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  85. Ekins R.P. Measurement of free ligands. USA.European Patent Applications, 123, 328/80300514.9, 1980.

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  86. Ealey P.A., Marshall N.J. and Ekins R.P. Comparison of the responses to the thyrotrophin and thyroid stimulating antibodies in the section cytochemical bioassay. Proceedings 163rd Meeting Society for Endocrinology, p.15, 1981.

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University College NHS Foundation Trust and University College London. (2012). Contributions to Medical and Scientific Literature. In: FESTSCHRIFT The Institute of Nuclear Medicine 50 Years. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25123-8_10

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