Zusammenfassung
Das akute Nierenversagen (»acute renal failure«) tritt gehäuft bei Intensivpatienten auf und wird durch eine verminderte Organdurchblutung und eine Vielzahl von Nephrotoxinen bedingt. Die Nierenfunktion hat einen hohen prädiktiven Wert für die Prognose des gesamten Krankheitsverlaufs. Gleichzeitig moduliert die Niere eine Vielzahl von Prozessabläufen im menschlichen Organismus und ist damit an der Pathophysiologie von Krankheitsabläufen beteiligt. Im Rahmen dieser Erkenntnisse wurde der Begriff des »acute renal failure« in der medizinischen Fachliteratur durch »acute kidney injury« (AKI) ersetzt. Der neue Begriff erlaubt die Beschreibung des schrittweisen Versagens der Niere, dessen Therapie neben der Behandlung der Grunderkrankung des Gesamtorganismus die apparative Nierenersatztherapie sowie supportive intensivmedizinische Maßnahmen umfasst.
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Kaufmann, I., Haller, M., Schelling, G. (2012). Akutes Nierenversagen und Nierenersatzverfahren. In: Rossaint, R., Werner, C., Zwißler, B. (eds) Die Anästhesiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21125-6_84
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