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Modeling and Simulations of the Dynamics of Growing Cell Clusters

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Advances in Cell Mechanics

Abstract

A phenomenological discrete model for the dynamics of growing cell clusters is presented. Each cell is modeled as a growing deformable solid which can interact mechanically with its neighbors by means of adhesion and repulsion forces. By defining simple behavior rules based on the age and the mechanical state of the cells, simple cluster dynamics can be reproduced. The framework is far from complete, but describes the essential features required for more complete mechanical simulations of cell ensembles.

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Author information

Authors and Affiliations

  1. Technical University of Madrid, Spain

    Ignacio Romero & Juan J. Arribas

Authors
  1. Ignacio Romero
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  2. Juan J. Arribas
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Corresponding author

Correspondence to Ignacio Romero .

Editor information

Editors and Affiliations

  1. Department of Civil and Environmental Engineering, The University of California at Berkeley, USA

    Shaofan Li

  2. Centre for Mechanics, Smart Structures and Microsystems, Cape Peninsula University of Technology, Cape Town, South Africa

    Bohua Sun

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© 2011 Higher Education Press, Beijing and Springer-Verlag Berlin Heidelberg

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Romero, I., Arribas, J.J. (2011). Modeling and Simulations of the Dynamics of Growing Cell Clusters. In: Li, S., Sun, B. (eds) Advances in Cell Mechanics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-17590-9_1

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  • DOI: https://doi.org/10.1007/978-3-642-17590-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-17589-3

  • Online ISBN: 978-3-642-17590-9

  • eBook Packages: EngineeringEngineering (R0)

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