Zusammenfassung
Die juvenile Osteoporose tritt im Verhältnis zur Osteoporose des älteren Menschen erheblich seltener auf. Eine Erkrankung stellt aber für das betroffene Kind und dessen Familie eine erhebliche Belastung dar. Die meisten juvenilen Osteoporosen sind sekundärer Form, ausgenommen die idiopathische juvenile Osteoporose, bei der es sich um eine nichthereditäre Form der erhöhten Knochenbrüchigkeit im Kindesalter handelt, für die keine auslösende Ursache verantwortlich gemacht werden kann. Die häufigsten Ursachen sind entweder durch eine entsprechende Grunderkrankung, z. B. rheumatoide Arthritis oder iatrogen durch osteokatabole Medikamente bedingt, an erster Stelle Kortison.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Bachrach LK, Ward LM (2009) Clinical review 1: Bisphosphonate use in childhood osteoporosis. J Clin Endocrinol Metab 94: 400–409
Burnham JM, Shults J, Semeao E, Foster B, Zemel BS, Stallings VA, Leonard MB (2004) Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body composition. J Bone Miner Res 19: 1961–1968
Castillo H, Samson-Fang L (2009) American Academy for Cerebral Palsy and Developmental Medicine Treatment Outcomes Committee Review Panel. Effects of bisphosphonates in children with osteogenesis imperfecta: an AACPDM systematic review. Dev Med Child Neurol 51(1): 17–29
Glorieux FH, Bishop NJ, Plotkin H, Chabot G, Lanoue G, Travers R (1998) Cyclic administration of pamidronate in children with severe osteogenesis imperfecta. N Engl J Med 339(14): 947–952
Hind K, Burrows M (2007) Weight-bearing exercise and bone mineral accrual in children and adolescents: a review of controlled trials. Bone 40(1): 14–27
Högler W, Briody J, Woodhead HJ, Chan A, Cowell CT (2003) Importance of lean mass in the interpretation of total body densitometry in children and adolescents. J Pediatr 143: 81–88
Loftus J, Allen R, Hesp R et al. (1991) Randomized, double-blind trial of deflazacort versus prednisone in juvenile chronic (or rheumatoid) arthritis: pa relatively bone-sparing effect of deflazacort. Pediatrics 88(3): 428–436
Institute of Medicine (1997) Dietary reference intakes for calcium, phosphorus, magnesium, vitamin D and fluoride. National Academic Press, Washington, DC
Thornton J, Ashcroft D, O’Neill T et al. (2008) A systematic review of the effectiveness of strategies for reducing fracture risk in children with juvenile idiopathic arthritis with additional data on long-term risk of fracture and cost of disease management. Health Technology Assessment Vol. 12: No. 3
Leonard MB, Feldman HI, Shults J, Zemel BS, Foster BJ, Stallings VA (2004) Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. NEJM 351: 868–875
LoCascio V, Ballanti P, Milani S, Bertoldo F, LoCascio C, Zanolin EM, Bonucci E (1998) A histomorphometric long-term longitudinal study of trabecular bone loss in glucocorticoid-treated patients: prednisone versus deflazacort. Calcif Tissue Int 62(3): 199–204
MacKelvie KJ, Petit MA, Khan KM, Beck TJ, McKay HA (2004) Bone mass and structure are enhanced following a 2-year randomized controlled trial of exercise in prepubertal boys. Bone 34(4): 755–764
Munns CF, Cowell CT (2005) Prevention and treatment of osteoporosis in chronically ill children. J Musculoskelet Neuronal Interact 5: 26–72
Semler O, Land C, Schönau E (2007) Bisphosphonate therapy for children and adolescents with primary and secondary osteoporotic diseases. Orthopäde 36(2): 146–151
Ward K, Alsop C, Caulton J, Rubin C, Adams J, Mughal Z (2004) Low magnitude mechanical loading is osteogenic in children with disabling conditions. J Bone Miner Res 19(3): 360–936
Ward L, Tricco AC, Phuong P et al. (2007) Bisphosphonate therapy for children and adolescents with secondary osteoporosis. Cochrane Database Syst Rev 17(4): CD005324
Zemel B, Bass S, Binkley T et al. (2008) Peripheral quantitative computed tomography in children and adolescents: the 2007 ISCD Pediatric Official Positions. J Clin Densitom 11: 59–74
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Niedhart, C., Maus, U. (2010). Sekundäre juvenile Osteoporose. In: Fortbildung Osteologie. Fortbildung Osteologie, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05385-6_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-05385-6_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-05384-9
Online ISBN: 978-3-642-05385-6
eBook Packages: Medicine (German Language)