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Optical Coherence Tomography

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Intraocular Inflammation

Abstract

The evaluation of the optical coherence tomography (OCT) is based on the identification of differences in the relative reflectivity of different tissue layers and morphological changes in tissue structures. So the examination is able to localize and grossly demarcate inflammation in the vitreous cavity (by its dynamic analysis) or beneath retinal layers as well as detail retinal changes on the chronic phases of retinal disease like fibrosis, atrophy, or retinal edema.

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References

  1. Gupta V, Gupta P, Singh R, Dogra MR, Gupta A (2008) Spectral-domain Cirrus high-definition optical coherence tomography is better than time-domain Stratus optical coherence tomography for evaluation of macular pathologic features in uveitis. Am J Ophthalmol 145(6):1018–22

    Article  PubMed  Google Scholar 

  2. Gallagher MJ, Yilmaz T, Cervantes-Castaneda RA, Foster CS (2007) The characteristic features of optical coherence tomography in posterior uveitis. Br J Ophthalmol 91(12):1680–5

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  3. Reinthal EK, Volker M, Freudenthaler N, Grub M, Zierhut M, Schlote T (2004) Optical coherence tomography in the diagnosis and follow-up of patients with uveitic macular edema. Ophthalmologe 101(12):1181–8

    Article  CAS  PubMed  Google Scholar 

  4. Kiernan DF, Mieler WF, Hariprasad SM (2010) Spectral-domain optical coherence tomography: a comparison of modern high-resolution retinal imaging systems. Am J Ophthalmol 149(1):18–31

    Article  PubMed  Google Scholar 

  5. Han IC, Jaffe GJ (2009) Comparison of spectral- and time-domain optical coherence tomography for retinal thickness measurements in healthy and diseased eyes. Am J Ophthalmol 147(5):847–58, 58e1

    Article  PubMed  Google Scholar 

  6. Spaide RF, Koizumi H, Pozzoni MC (2008) Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol 146:496–500

    Article  PubMed  Google Scholar 

  7. Margolis R, Spaide RF (2009) A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol 147:811–815

    Article  PubMed  Google Scholar 

  8. Malinowski SM, Pulido JS, Folk JC (1993) Long-term visual outcome and complications associated with pars planitis. Ophthalmology 100(6):818–24; discussion 825

    Article  CAS  PubMed  Google Scholar 

  9. Antcliff RJ, Stanford MR, Chauhan DS, Graham EM, Spalton DJ, Shilling JS et al (2000) Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis. Ophthalmology 107(3):593–9

    Article  CAS  PubMed  Google Scholar 

  10. Markomichelakis NN, Halkiadakis I, Pantelia E, Peponis V, Patelis A, Theodossiadis P et al (2004) Patterns of macular edema in patients with uveitis: qualitative and quantitative assessment using optical coherence tomography. Ophthalmology 111(5):946–53

    Article  PubMed  Google Scholar 

  11. Tran TH, de Smet MD, Bodaghi B, Fardeau C, Cassoux N, Lehoang P (2008) Uveitic macular oedema: correlation between optical coherence tomography patterns with visual acuity and fluorescein angiography. Br J Ophthalmol 92(7):922–7

    Article  CAS  PubMed  Google Scholar 

  12. Iannetti L, Accorinti M, Liverani M, Caggiano C, Abdulaziz R, Pivetti-Pezzi P (2008) Optical coherence tomography for classification and clinical evaluation of macular edema in patients with uveitis. Ocul Immunol Inflamm 16(4):155–60

    Article  PubMed  Google Scholar 

  13. Yamaguchi Y, Otani T, Kishi S (2007) Tomographic features of serous retinal detachment with multilobular dye pooling in acute Vogt-Koyanagi-Harada disease. Am J Ophthalmol 144(2):260–5

    Article  PubMed  Google Scholar 

  14. Gupta V, Gupta A, Gupta P, Sharma A (2009) Spectral-domain cirrus optical coherence tomography of choroidal striations seen in the acute stage of Vogt-Koyanagi-Harada disease. Am J Ophthalmol 147(1):148–53.e2

    Article  PubMed  Google Scholar 

  15. Dhingra N, Kelly S, Majid MA, Bailey CB, Dick AD (2010) Inflammatory choroidal neovascular membrane in posterior uveitis-pathogenesis and treatment. Indian J Ophthalmol 58(1):3–10

    Article  PubMed Central  PubMed  Google Scholar 

  16. Dees C, Arnold JJ, Forrester JV, Dick AD (1998) Immunosuppressive treatment of choroidal neovascularization associated with endogenous posterior uveitis. Arch Ophthalmol 116(11):1456–61

    Article  CAS  PubMed  Google Scholar 

  17. Kramer M, Axer-Siegel R, Jaouni T, Reich E, Hemo I, Priel E et al (2010) Bevacizumab for choroidal neovascularization related to inflammatory diseases. Retina 30(6):938–44

    Article  PubMed  Google Scholar 

  18. Gass JD (1994) Biomicroscopic and histopathologic considerations regarding the feasibility of surgical excision of subfoveal neovascular membranes. Am J Ophthalmol 118(3):285–98

    Article  CAS  PubMed  Google Scholar 

  19. Orefice JL, Costa RA, Orefice F, Campos W, Da Costa-Lima D Jr, Scott IU (2007) Vitreoretinal morphology in active ocular toxoplasmosis: a prospective study by optical coherence tomography. Br J Ophthalmol 91(6):773–80

    Article  PubMed Central  PubMed  Google Scholar 

  20. Orefice JL, Costa RA, Campos W, Calucci D, Scott IU, Orefice F (2006) Third-generation optical coherence tomography findings in punctate retinal toxoplasmosis. Am J Ophthalmol 142(3):503–5

    Article  PubMed  Google Scholar 

  21. Gomez ML, Mojana F, Bartsch DU, Freeman WR (2009) Imaging of long-term retinal damage after resolved cotton wool spots. Ophthalmology 116(12):2407–14

    Article  PubMed Central  PubMed  Google Scholar 

  22. Kozak I, Bartsch DU, Cheng L, Kosobucki BR, Freeman WR (2005) Objective analysis of retinal damage in HIV-positive patients in the HAART era using OCT. Am J Ophthalmol 139(2):295–301

    Article  PubMed Central  PubMed  Google Scholar 

  23. Arantes TE, Garcia CR, Mello PA, Muccioli C (2010) Structural and functional assessment in HIV-infected patients using optical coherence tomography and frequency-doubling technology perimetry. Am J Ophthalmol 149(4):571–576

    Article  Google Scholar 

  24. Romano AC, Belfort RN, Maia A, Moraes NB, Farah M, Belfort R Jr (2009) En-face, a novel OCT imaging approach to evaluate patients with retinal diseases. Invest Ophthalmol Vis Sci 50 (E-Abstract 341)

    Google Scholar 

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Correspondence to Cristina Muccioli MD .

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Muccioli, C. et al. (2016). Optical Coherence Tomography. In: Zierhut, M., Pavesio, C., Ohno, S., Orefice, F., Rao, N. (eds) Intraocular Inflammation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75387-2_11

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  • DOI: https://doi.org/10.1007/978-3-540-75387-2_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-75385-8

  • Online ISBN: 978-3-540-75387-2

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