Abstract
The pigmented villonodular synovitis (PVNS) is a very uncommon non-malignant, but proliferative disease, eventually with locally aggressive behavior, that can affect synovial-lined joints, bursae and tendon sheaths. PVNS is well characterized by a hyperplastic synovium of the affected joint, frequent and large effusions and para-articular bony erosions. The first physician ever to describe the lesion was the French surgeon Chassaignac in 1852 (1804–1879), but he overstated its biologic potential in referring to it as a “cancer of the tendon sheath.” It took almost 100 years for the first correct clinical description of PVNS as a distinct disease entity to be given by Jaffe and coworkers in 1941 [20]. They proposed the actual name and described the typical clinical and histological findings.
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Oppenkowski, R., Seegenschmiedt, M.H. (2008). Pigmented Villonodular Synovitis (PVNS). In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_21
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DOI: https://doi.org/10.1007/978-3-540-68943-0_21
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