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Current and Emerging Technologies in Hematologic Testing

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Hematologic Challenges in the Critically Ill

Abstract

Hematologic testing informs management decisions made by clinicians managing critically ill patients. The technology underpinning such tests continuously evolves, so interpretation of results hinges on understanding the methodologies used and comparison to established standards. Hemoglobin concentration determination can be performed with point-of-care and noninvasive methods. These have varying agreement with laboratory-based methods. Patients treated with direct oral anticoagulants present a challenge as the action of these are not well differentiated using standard laboratory methods. Viscoelastic testing and some emerging tests may provide guidance for treating critically ill patients receiving direct oral anticoagulants.

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Authors and Affiliations

  1. UC Davis Medical Center, Department of Anesthesiology and Pain Medicine, Sacramento, CA, USA

    James E. Littlejohn MD PhD & Richard L. Applegate II MD

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  1. James E. Littlejohn MD PhD
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  2. Richard L. Applegate II MD
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Correspondence to Richard L. Applegate II MD .

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Editors and Affiliations

  1. Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Team Health Research Institute, Englewood, NJ, USA

    Aryeh Shander

  2. Department of Critical Care Medicine, Geisinger Health System, Danville, PA, USA

    Howard L. Corwin

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Littlejohn, J.E., Applegate, R.L. (2018). Current and Emerging Technologies in Hematologic Testing. In: Shander, A., Corwin, H. (eds) Hematologic Challenges in the Critically Ill. Springer, Cham. https://doi.org/10.1007/978-3-319-93572-0_4

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