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Biodegradable Metals for Orthopedic Applications

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Orthopedic Biomaterials

Abstract

A new round of studies on biodegradable metals from the end of last century has made remarkable progress as magnesium based alloys are now represented in orthopedic implants. The development is introduced in this chapter, including the degradation mechanism and its affecting factors, its bio-functions (promoting osteogenesis, antimicrobial and inhibiting tumor cell survival) and its orthopedic applications (bone fixation, bone substitute, osteomyelitis and Mg coating on bio-inert materials).

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Acknowledgement

The authors thank the financial support from the National Natural Science Foundation of China (No. 81401773, 31500777), National High Technology Research and Development Program of China (No. 2015AA033701), Key Program of China on Biomaterials Research and Tissue and Organ Replacement (No. 2016YFC1101804), CAS-Croucher Funding Scheme for Joint Laboratories (CAS 14303), Hong Kong RGC Collaborative Research Fund (CRF, C4028-14GF) and Institute of Metal Research, Chinese Academy of Sciences (No.2015-ZD01).

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Authors and Affiliations

  1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning, China

    Ke Yang, Lili Tan, Peng Wan, Xiaoming Yu & Zheng Ma

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  1. Ke Yang
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  2. Lili Tan
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  3. Peng Wan
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  4. Xiaoming Yu
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Correspondence to Ke Yang .

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Editors and Affiliations

  1. Department of Orthopedics, School of Medicine, West Virginia University, Morgantown, West Virginia, USA

    Bingyun Li

  2. Chemical Engineering, Northeastern University, Boston, Massachusetts, USA

    Thomas Webster

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Yang, K., Tan, L., Wan, P., Yu, X., Ma, Z. (2017). Biodegradable Metals for Orthopedic Applications. In: Li, B., Webster, T. (eds) Orthopedic Biomaterials. Springer, Cham. https://doi.org/10.1007/978-3-319-73664-8_11

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