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Renewable Biomaterials as Nanocarriers for Drug and Gene Delivery

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Drug and Gene Delivery to the Central Nervous System for Neuroprotection

Abstract

Recently, due to strong emphasis on environmental awareness worldwide, utilization of renewable feedstocks has been growing in the development of materials for various applications. Amphiphilic polymeric materials have been widely used as drug and gene delivery carriers. These materials can self-assemble into different nanostructures, such as micelles, nanospheres, hydrogels, nanocapsules and polymersomes, which can serve as reservoirs for various therapeutic agents. Among numerous materials that can be used to fabricate these systems, those from renewable resources are of particular interest, due to the increasing environmental concerns as well as their natural abundance and favorable properties including biocompatibility, biodegradability and non-toxicity. In this chapter, naturally occurring materials such as polysaccharides, vegetable oils, terpenes and proteins, and their applications as nano delivery systems are reviewed.

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Authors and Affiliations

  1. Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada, T6G 2P5

    Shimiao Zhang, Liejiang Jin, Muhammad Arshad & Aman Ullah Ph.D.

  2. Department of Chemical Engineering, McMaster University, Hamilton, ON, Canada, L8S 4L7

    Shimiao Zhang

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  1. Shimiao Zhang
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  2. Liejiang Jin
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  3. Muhammad Arshad
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  4. Aman Ullah Ph.D.
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Correspondence to Aman Ullah Ph.D. .

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Editors and Affiliations

  1. International Experimental Central Nervous System Injury & Repair (IECNSIR), Laboratory of Cerebrovascular Biology, Department of Surgical Sciences, Anesthesiology & Intensive Care Medicine, Uppsala University Hospital, Uppsala University, Uppsala, Sweden

    Hari S. Sharma

  2. Department of Clinical Neurosciences, University of Medicine and Pharmacy, Cluj-Napoca, Romania

    Dafin F. Muresanu

  3. International Experimental Central Nervous System Injury & Repair (IECNSIR), Laboratory of Cerebrovascular Biology, Department of Surgical Sciences, Anesthesiology & Intensive Care Medicine, Uppsala University Hospital, Uppsala University, Uppsala, Sweden

    Aruna Sharma

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Zhang, S., Jin, L., Arshad, M., Ullah, A. (2017). Renewable Biomaterials as Nanocarriers for Drug and Gene Delivery. In: Sharma, H., Muresanu, D., Sharma, A. (eds) Drug and Gene Delivery to the Central Nervous System for Neuroprotection. Springer, Cham. https://doi.org/10.1007/978-3-319-57696-1_1

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