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Implantable Medical Devices Treated with Antimicrobial Agents

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Antimicrobial Coatings and Modifications on Medical Devices

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Abstract

Implantable medical devices possess great utility for patients who require medical intervention and/or replacement of biological functions. Though providing a critical purpose, medical devices are prone to complications such as infection that often result in significant morbidity and mortality. Medical device-associated infections present a large challenge to the healthcare industry in terms of treatment and cost. Several approaches to mitigate infection have been explored and most focus on preventing initial colonization of the device with infectious microorganisms. One method that has been employed successfully in the medical device industry is the incorporation of antimicrobial agents in devices to inhibit or kill invading microbes. This chapter discusses current products in use in the healthcare field as well as some promising active agents that are in the beginning or advanced stages of market approval and release.

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Authors and Affiliations

  1. Global Advanced Engineering, Teleflex Inc., 1 Kendall Square, Cambridge, MA, 02139, USA

    Victoria E. Wagner

  2. Research & Development, Vascular Division, Teleflex Inc., 2400 Bernville Rd, Reading, PA, 19605, USA

    Nisha Gupta

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  1. Global Advanced Engineering, Teleflex Inc., Cambridge, Massachusetts, USA

    Zheng Zhang

  2. Global Advanced Engineering, Teleflex Inc., Cambridge, Massachusetts, USA

    Victoria E. Wagner

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Wagner, V.E., Gupta, N. (2017). Implantable Medical Devices Treated with Antimicrobial Agents. In: Zhang, Z., Wagner, V. (eds) Antimicrobial Coatings and Modifications on Medical Devices. Springer, Cham. https://doi.org/10.1007/978-3-319-57494-3_5

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