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Macromolecular Imprinting for Improved Health Security

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Biosensors for Security and Bioterrorism Applications

Abstract

There is a growing demand for rapid and reliable methods of determination of microorganism contamination of waters and food products to ensure quality assurance and to improve the health care system in general. Majority of the available methods for determination of microorganisms in foods are time consuming and expensive. In recent years, different approaches have been attempted to develop alternative procedures for determination of microorganisms. In the present chapter, we summarize the recent achievements in the development of synthetic recognition systems based devices for monitoring the presence of microorganisms, such as bacteria, bacteriophages, and viruses, in waters and food products. Molecular imprinting has been most successful in devising relevant synthetic receptors. Application of these recognition systems for determination of microorganisms is herein described in detail.

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Abbreviations

ASPV:

Apple stem pitting virus

CV:

Cyclic voltammetry

cfu:

Colony forming unit

DMSO:

Dimethylsulfoxide

DLS:

Dynamic light scattering

DNA:

Deoxyribonucleic acid

µIDC:

Micro interdigited capacitor

EIS:

Electrochemical impedance spectroscopy

ELISA:

Enzyme-linked immunosorbent assay

FESEM:

Field emission scanning electron microscopy

LOD:

Limit of detection

LOQ:

Limit of quantitation

MIP:

Molecularly imprinted polymer

MIPPy:

Molecularly imprinted polypyrrole

OPPy:

Overoxidized polypyrrole

PM:

Piezoelectric microgravimetry

PMA:

Poly(methacrylic acid)

PPy:

Polypyrrole

PSS:

Poly(styrene sulfonate)

PVC:

Poly(vinyl chloride)

PVP:

Polyvinylpirrolidone

SG:

Sol-gel

SEM:

Scanning electron microscopy

SiNP:

Silica nanoparticle

SPR:

Surface plasmon resonance

SRB:

Sulfate-reducing bacteria

TMV:

Tobacco mosaic virus

TYMV:

Turnip yellow mosaic virus

VLP:

Virus like particle

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Acknowledgments

We thank the Polish National Science Centre, NCN (Grant Nos. 2013/11/N/ST5/01907 to Z.I., and 2014/15/B/NZ7/01011 to W.K.), and the Ministry of Science and Higher Education of Poland (Grant No. 0005/E-64/9/2014, and IP 2014-041473 to P.S.S.) and the U.S. National Science Foundation (Grant No. CHE-1401188 to F.D.).

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Authors and Affiliations

  1. Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland

    Piyush Sindhu Sharma, Zofia Iskierko & Wlodzimierz Kutner

  2. Department of Chemistry, University of North Texas, 1155, Union Circle, Denton, #305070 TX 76203-5017, USA

    Francis D’Souza

  3. Faculty of Mathematics and Natural Sciences, School of Sciences, Cardinal Stefan Wyszynski University in Warsaw, Wóycickiego 1/3, 01-815, Warsaw, Poland

    Wlodzimierz Kutner

Authors
  1. Piyush Sindhu Sharma
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  2. Zofia Iskierko
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  3. Francis D’Souza
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  4. Wlodzimierz Kutner
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Corresponding authors

Correspondence to Piyush Sindhu Sharma , Francis D’Souza or Wlodzimierz Kutner .

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Editors and Affiliations

  1. University of Athens, Athens, Greece

    Dimitrios P. Nikolelis

  2. Lab. of Inorganic & Analytic Chemistry, National Technical University of Athens, Athens, Greece

    Georgia-Paraskevi Nikoleli

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Sharma, P.S., Iskierko, Z., D’Souza, F., Kutner, W. (2016). Macromolecular Imprinting for Improved Health Security. In: Nikolelis, D., Nikoleli, GP. (eds) Biosensors for Security and Bioterrorism Applications. Advanced Sciences and Technologies for Security Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-28926-7_7

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