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Towards Automatic Assessment of the Mitral Valve Coaptation Zone from 4D Ultrasound

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Functional Imaging and Modeling of the Heart (FIMH 2015)

Abstract

The coaptation zone is the part of the two mitral valve leaflets that collide during the cardiac cycle. It is an important parameter for the valve’s function and closing capability, but difficult to assess. In this work, we present an automatic approach for leaflet segmentation from 4D ultrasound images, which incorporates steps for coaptation zone modelling and allows determining the coaptation zone from the resulting leaflet surface. The method segments the leaflets over the whole cardiac cycle given a previously segmented annulus model. To provide a meaningful analysis of the coaptation line assessment, the mean error between ground truth model and segmented model has been computed for each leaflet separately. For the anterior leaflet, we achieved a mean error of \(1.16 \pm 0.38\) mm and \(1.24 \pm 0.37\) mm for the posterior leaflet, respectively.

S. Engelhardt and N. Lichtenberg—These authors contributed equally to this work.

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References

  1. Boykov, Y., Kolmogorov, V.: An experimental comparison of min-cut/max-flow algorithms for energy minimization in vision. IEEE Trans. Pattern Anal. Mach. Intell. 26(9), 1124–1137 (2004)

    Article  Google Scholar 

  2. Chen, L., McCulloch, A.D., May-Newman, K.: Nonhomogeneous deformation in the anterior leaflet of the mitral valve. Ann. Biomed. Eng. 32(12), 1599–1606 (2004)

    Article  Google Scholar 

  3. Cobey, F.C., Swaminathan, M., Phillips-Bute, B., et al.: Quantitative assessment of mitral valve coaptation using three-dimensional transesophageal echocardiography. Ann. Thorac. Surg. 97(6), 1998–2004 (2014)

    Article  Google Scholar 

  4. Gogoladze, G., Dellis, S.L., Donnino, R., et al.: Analysis of the mitral coaptation zone in normal and functional regurgitant valves. Ann. Thorac. Surg. 89(4), 1158–1161 (2010)

    Article  Google Scholar 

  5. Graser, B., Wald, D., Al-Maisary, S., Grossgasteiger, M., de Simone, R., Meinzer, H.-P., Wolf, I.: Using a shape prior for robust modeling of the mitral annulus on 4D ultrasound data. Int. J. Comput. Assist. Radiol. Surg. 9(4), 635–644 (2013)

    Google Scholar 

  6. Ionasec, R.I., Voigt, I., Georgescu, B., et al.: Patient-specific modeling and quantification of the aortic and mitral valves from 4-D cardiac CT and TEE. IEEE Trans. Med. Imaging 29(9), 1636–1651 (2010)

    Article  Google Scholar 

  7. Nielsen, S.L., Nygaard, H., Mandrup, L., et al.: Mechanism of incomplete mitral leaflet coaptation - interaction of chordal restraint and changes in mitral leaflet coaptation geometry. J. Biomed. Eng. 124(5), 596–608 (2002)

    Google Scholar 

  8. Nolden, M., Zelzer, S., Seitel, A., Wald, D., et al.: The medical imaging interaction toolkit: challenges and advances: 10 years of open-source development. Int. J. Comput. Assist. Radiol. Surg. 8(4), 607–620 (2013)

    Article  Google Scholar 

  9. Pouch, A., Wang, H., Takabe, M., et al.: Fully automatic segmentation of the mitral leaflets in 3D transesophageal echocardiographic images using multi-atlas joint label fusion and deformable medial modeling. Med. Image Anal. 18(1), 118–129 (2014)

    Article  Google Scholar 

  10. Saito, K., Okura, H., Watanabe, N., Obase, K., et al.: Influence of chronic tethering of the mitral valve on mitral leaflet size and coaptation in functional mitral regurgitation. JACC: Cardiovasc. Imaging 5(4), 337–345 (2012)

    Google Scholar 

  11. Schneider, R.J., Burke, W.C., Marx, G.R., del Nido, P.J., Howe, R.D.: Modeling mitral valve leaflets from three-dimensional ultrasound. In: Metaxas, D.N., Axel, L. (eds.) FIMH 2011. LNCS, vol. 6666, pp. 215–222. Springer, Heidelberg (2011)

    Chapter  Google Scholar 

  12. Schneider, R.J., Perrin, D.P., Vasilyev, N.V., et al.: Mitral annulus segmentation from 3D ultrasound using graph cuts. IEEE Trans. Med. Imaging 29(9), 1676–1687 (2010)

    Article  Google Scholar 

  13. Schneider, R.J., Tenenholtz, N.A., Perrin, D.P., Marx, G.R., del Nido, P.J., Howe, R.D.: Patient-specific mitral leaflet segmentation from 4D ultrasound. In: Fichtinger, G., Martel, A., Peters, T. (eds.) MICCAI 2011, Part III. LNCS, vol. 6893, pp. 520–527. Springer, Heidelberg (2011)

    Chapter  Google Scholar 

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Acknowlegdements

This research received support from the German Research Foundation (DFG), grant ME 833/12-2, SI 1349/1-2 and by the Collaborative Research Centre SFB/TRR 125 Cognition Guided Surgery within project B01.

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Correspondence to Sandy Engelhardt or Nils Lichtenberg .

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Engelhardt, S. et al. (2015). Towards Automatic Assessment of the Mitral Valve Coaptation Zone from 4D Ultrasound. In: van Assen, H., Bovendeerd, P., Delhaas, T. (eds) Functional Imaging and Modeling of the Heart. FIMH 2015. Lecture Notes in Computer Science(), vol 9126. Springer, Cham. https://doi.org/10.1007/978-3-319-20309-6_16

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  • DOI: https://doi.org/10.1007/978-3-319-20309-6_16

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-20309-6

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