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The Use of Isolated Heart Models and Anatomical Specimens as Means to Enhance the Design and Testing of Cardiac Devices

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Handbook of Cardiac Anatomy, Physiology, and Devices

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Abstract

In recent years, the use of perfusion-fixed cadaveric specimens and isolated heart models has helped to develop an improved understanding of the device-tissue interface and has also contributed to the rapid evolution of surgically and percutaneously delivered cardiac therapies. This chapter describes a novel series of techniques utilized within the Visible Heart® laboratory by engineers, scientists, and anatomists to visualize and analyze the heart and assess potential repair or replacement therapies. The study of reanimated large mammalian hearts (including human hearts) and specially prepared anatomical specimens, using various clinical and nonclinical imaging modalities, has provided feedback for design engineers and clinicians that seek to develop and/or employ cardiac therapies for patients with acquired or congenital heart disease.

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Author information

Authors and Affiliations

  1. Medtronic, Inc., 8200 Coral Sea Street NE, Mounds View, Minneapolis, MN, 55112, USA

    Michael G. Bateman PhD, Michael D. Eggen PhD & Julianne H. Spencer PhD

  2. Department of Surgery, University of Minnesota, Minneapolis, MN, USA

    Tinen L. Iles BS & Paul A. Iaizzo PhD

Authors
  1. Michael G. Bateman PhD
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  2. Michael D. Eggen PhD
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  3. Julianne H. Spencer PhD
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  4. Tinen L. Iles BS
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  5. Paul A. Iaizzo PhD
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Corresponding author

Correspondence to Michael G. Bateman PhD .

Editor information

Editors and Affiliations

  1. B172 Mayo, MMC 195, University of Minnesota Department of Surgery, Minneapolis, Minnesota, USA

    Paul A. Iaizzo

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© 2015 Springer International Publishing Switzerland

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Bateman, M.G., Eggen, M.D., Spencer, J.H., Iles, T.L., Iaizzo, P.A. (2015). The Use of Isolated Heart Models and Anatomical Specimens as Means to Enhance the Design and Testing of Cardiac Devices. In: Iaizzo, P. (eds) Handbook of Cardiac Anatomy, Physiology, and Devices. Springer, Cham. https://doi.org/10.1007/978-3-319-19464-6_41

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