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Vitamin E (Tocopherol): Implications in Cardiovascular Health and Neuroprotection

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Lipophilic Vitamins in Health and Disease

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 28))

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Abstract

Vitamin E is a lipophilic vitamin that helps scavenge cells from ROS and causes lipid peroxidation. Its non-enzymatic antioxidant activity makes it helpful in treating disorders such as Alzheimer's, Huntington's, Parkinson's, and many types of cardiovascular impairments. Different types of prospective, randomized clinical, and double-anonymized trials were successful because an isoform of vitamin E called α-tocopherol has the most protective effect against lipid peroxidative damage. Vitamin E (α-tocopherol) has been researched in numerous clinical studies and evaluated in the current literature as a medicinal agent for its neuroprotective and cardioprotective functions.

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Acknowledgements

This study was supported by the Ministry of Science and Technology, Taiwan (NSTC 111-2320-B-037-008-MY2), Taiwan. The Orthopedic Research Center and Regeneration Medicine and Cell Therapy Research Center in Kaohsiung Medical University is acknowledged for its research resources and equipment. We appreciate the support from the Orthopedic Research Center and the Department of Physiology, the Regeneration Medicine and Cell Therapy Research Center, the Graduate Institute of Medicine, and the College of Medicine of Kaohsiung Medical University, Kaohsiung City, Taiwan. The authors express their profound gratitude to the Management, Dean, Director of Medical Research, of Aarupadai Veedu Medical College and Hospital for their unwavering and invaluable support

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Authors and Affiliations

  1. Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, Tamil Nadu, 632115, India

    Ranganathan Parameswari, Ranganathan Babaujanarthanam & Prithiviraj Nagarajan

  2. Orthopedic Research Center, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, 80708

    Mariadoss Arokia Vijaya Anand & Chau-Zen Wang

  3. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan

    Chau-Zen Wang

  4. Regeneration Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan

    Chau-Zen Wang

  5. Department of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan

    Chau-Zen Wang

  6. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, 80708, Taiwan

    Chau-Zen Wang

  7. College of Professional Studies, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan

    Chau-Zen Wang

  8. Department of Medical Biotechnology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (Deemed to be University), Kirumampakkam, Puducherry, 607402, India

    Prithiviraj Nagarajan

Authors
  1. Ranganathan Parameswari
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  2. Mariadoss Arokia Vijaya Anand
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  3. Chau-Zen Wang
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  4. Ranganathan Babaujanarthanam
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  5. Prithiviraj Nagarajan
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Contributions

Ranganathan Parameswari: Conceptualization, Methodology, Investigation, Data Curation, Writing—Original Draft, Visualization.

Mariadoss Arokia Vijaya Anand: Conceptualization, Methodology, Writing—Review and Editing, Supervision.

Chau-Zen Wang: Writing—Review and Editing, Supervision.

Ranganathan Babaujanarthanam: Methodology, Writing—Review and Editing, Resources.

Prithiviraj Nagarajan: Conceptualization, Writing—Review and Editing, Resources.

Corresponding authors

Correspondence to Mariadoss Arokia Vijaya Anand or Prithiviraj Nagarajan .

Editor information

Editors and Affiliations

  1. Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, MB, Canada

    Paramjit S. Tappia

  2. California State University Los Angeles, Los Angeles, CA, USA

    Anureet K. Shah

  3. Institute of Cardiovascular Science, St. Boniface Hospital, Winnipeg, MB, Canada

    Naranjan S. Dhalla

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Parameswari, R., Arokia Vijaya Anand, M., Wang, CZ., Babaujanarthanam, R., Nagarajan, P. (2024). Vitamin E (Tocopherol): Implications in Cardiovascular Health and Neuroprotection. In: Tappia, P.S., Shah, A.K., Dhalla, N.S. (eds) Lipophilic Vitamins in Health and Disease. Advances in Biochemistry in Health and Disease, vol 28. Springer, Cham. https://doi.org/10.1007/978-3-031-55489-6_12

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