Abstract
Pressure generation via instillation of irrigation during percutaneous nephrolithotomy is necessary for procedural safety and efficacy; termed intra-renal pressure (IRP). As iatrogenic pressures rise above physiologic levels intra-renal reflux, or fluid transposition outside of the collecting system, can occur. This shift of fluid and endotoxins, if present, has implications on post-operative pain/recovery, infectious and inflammatory responses, and systemic fluid/electrolyte imbalances. Numerous ex vivo human and in vivo animal studies have evaluated pressure thresholds for the three subtypes of intrarenal reflux: pyelovenous backflow, pyelosinuous backflow and intra-renal backflow. Knowledge and mitigation of procedural factors that lead to pressure rise during PCNL allows Urologists to minimize complications associated with elevated IRP.
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Appreciation to Pradeep Sharma for his assistance in medical illustration for this chapter.
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Riedinger, E., Osther, P.J.S., Knudsen, B. (2023). Intra-renal Pressure. In: Denstedt, J.D., Liatsikos, E.N. (eds) Percutaneous Renal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-40542-6_29
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